Single nucleotide polymorphisms distinguish multiple dopamine transporter alleles in primates: implications for association with attention deficit hyperactivity disorder and other neuropsychiatric disorders

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

1996 • 2,452 citations

Association of attention-deficit disorder and the dopamine transporter gene.

1995 • 1,023 citations

Dopamine Transporter Occupancies in the Human Brain Induced by Therapeutic Doses of Oral Methylphenidate

1998 • 878 citations

Role of Serotonin in the Paradoxical Calming Effect of Psychostimulants on Hyperactivity

1999 • 873 citations

Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR

1992 • 718 citations

The Role of Locus Coeruleus in the Regulation of Cognitive Performance

1999 • 707 citations

Locus coeruleus neurons in monkey are selectively activated by attended cues in a vigilance task

1994 • 639 citations

The human serotonin transporter gene linked polymorphism (5-HTTLPR) shows ten novel allelic variants

2000 • 622 citations

Effects of Methylphenidate on Extracellular Dopamine, Serotonin, and Norepinephrine: Comparison with Amphetamine

1997 • 613 citations

Genotype Influences In Vivo Dopamine Transporter Availability in Human Striatum

2000 • 550 citations

Attention-deficit/hyperactivity disorder (adhd) as a noradrenergic disorder

1999 • 502 citations

Confirmation of association between attention deficit hyperactivity disorder and a dopamine transporter polymorphism

1997 • 498 citations

Association and Linkage of the Dopamine Transporter Gene and Attention-Deficit Hyperactivity Disorder in Children: Heterogeneity owing to Diagnostic Subtype and Severity

1998 • 467 citations

Catecholamine uptake by synaptosomes in homogenates of rat brain: stereospecificity in different areas.

1969 • 445 citations

Toward a Pathophysiology of Attention-Deficit/Hyperactivint Disorder

1997 • 399 citations

Mapping susceptibility loci in attention deficit hyperactivity disorder: preferential transmission of parental alleles at DAT1, DBH and DRD5 to affected children

1999 • 390 citations

Association of the dopamine receptor D4 (DRD4) gene with a refined phenotype of attention deficit hyperactivity disorder (ADHD): a family-based approach

1998 • 383 citations

A serotonin transporter gene intron 2 polymorphic region, correlated with affective disorders, has allele-dependent differential enhancer-like properties in the mouse embryo

1999 • 372 citations

Attention-deficit/hyperactivity disorder: a life-span perspective.

1998 • 352 citations

Anti-hyperactivity medication: methylphenidate and amphetamine

1998 • 262 citations

Association of the Dopamine Transporter Gene (DAT1) With Poor Methylphenidate Response

1999 • 256 citations

Dopamine D₄ Gene 7-Repeat Allele and Attention Deficit Hyperactivity Disorder

1999 • 243 citations

Effects of cocaine and related drugs in nonhuman primates. I. [3H]cocaine binding sites in caudate-putamen.

1989 • 236 citations

Evidence that the dopamine D4 receptor is a susceptibility gene in attention deficit hyperactivity disorder

1998 • 222 citations

Dopamine DRD4 receptor polymorphism and attention deficit hyperactivity disorder

1998 • 219 citations

A genetic association for cigarette smoking behavior.

1999 • 203 citations

Genetic Association between Dopamine Transporter Protein Alleles and Cocaine-Induced Paranoia

1994 • 198 citations

Altered dopaminergic function in the prefrontal cortex, nucleus accumbens and caudate-putamen of an animal model of attention-deficit hyperactivity disorder — the spontaneously hypertensive rat

1995 • 198 citations

Global variation of a 40-bp VNTR in the 3′-untranslated region of the dopamine transporter gene (SLC6A3)

1999 • 184 citations

Spontaneously hypertensive rats (SHR) as a putative animal model of childhood hyperkinesis: SHR behavior compared to four other rat strains

1993 • 153 citations

Structure and organization of the gene encoding human dopamine transporter

1997 • 147 citations

A 40-nucleotide repeat polymorphism in the human dopamine transporter gene

1993 • 146 citations

VNTR (variable number of tandem repeat) sequences as transcriptional, translational, or functional regulators

1998 • 121 citations

Polymorphisms in the dopamine, serotonin, and norepinephrine transporter genes and their relationships to monoamine metabolite concentrations in CSF of healthy volunteers

1998 • 97 citations

Association of a polymorphism in the dopamine‐transporter gene with parkinson's disease

1997 • 96 citations

Early androgen treatment decreases cognitive function and catecholamine innervation in an animal model of ADHD

2000 • 93 citations

Identification of a novel polymorphism of the human dopamine transporter (DAT1) gene and the significant association with alcoholism

1999 • 92 citations

Population Studies of Polymorphisms at Loci of Neuropsychiatric Interest (Tryptophan Hydroxylase (TPH), Dopamine Transporter Protein (SLC6A3), D3 Dopamine Receptor (DRD3), Apolipoprotein E (APOE), μ Opioid Receptor (OPRM1), and Ciliary Neurotrophic Factor (CNTF))

1998 • 78 citations

Dopamine transporter gene polymorphisms are not associated with polysubstance abuse

1993 • 62 citations

Genotypic association between dopamine transporter gene polymorphisms and schizophrenia

1997 • 60 citations

Polymorphisms of dopamine receptor and transporter genes and Parkinson's disease

1995 • 47 citations

Variable number tandem repeat dopamine transporter gene polymorphism and Parkinson's disease: no association found

1999 • 38 citations

Human dopamine transporter gene polymorphism (VNTR) and alcoholism

1997 • 38 citations

Dopamine transporter gene polymorphism and psychiatric symptoms seen in schizophrenic patients at their first episode

1996 • 38 citations

Novelty Seeking and a Dopamine Transporter Gene Polymorphism (DAT1)

1997 • 27 citations

Polymorphism of Dopamine Receptors and Transporter Genes in Neuropsychiatric Diseases

1997 • 24 citations

Lack of association between dopamine transporter gene polymorphisms and delusional disorder.

1998 • 19 citations

Lack of association between dopamine transporter gene polymorphisms and delusional disorder

1998 • 16 citations

Spontaneous hyperthyroidism in an aged male and femaleMacaca mulatta

1998 • 11 citations

DNA sequence polymorphisms in genes involved in the regulation of dopamine and serotonin metabolism in rhesus macaques

1999 • 10 citations