Site-directed mutagenesis of the -10 region of the lacUV5 promoter. Introduction of dA4.dT4 tract suppresses open complex formation.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Rapid procedure for detection and isolation of large and small plasmids

1981 • 2,840 citations

Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis

1983 • 2,609 citations

Compilation and analysis ofEscherichia colipromoter DNA sequences

1983 • 2,228 citations

The locus of sequence-directed and protein-induced DNA bending

1984 • 1,453 citations

Procedure for the rapid, large-scale purification of Escherichia coli DNA-dependent RNA polymerase involving polymin P precipitation and DNA-cellulose chromatography

1975 • 1,157 citations

DNA bending at adenine · thymine tracts

1986 • 1,032 citations

Analysis of E.Coli Pormoter sequences

1987 • 1,029 citations

MECHANISM AND CONTROL OF TRANSCRIPTION INITIATION IN PROKARYOTES

1985 • 1,012 citations

The structure of an oligo(dA)·oligo(dT) tract and its biological implications

1987 • 975 citations

E. coli RNA polymerase interacts homologously with two different promoters

1980 • 911 citations

A bifurcated hydrogen-bonded conformation in the d(A.T) base pairs of the DNA dodecamer d(CGCAAATTTGCG) and its complex with distamycin.

1987 • 671 citations

The gapped duplex DNA approach to oligonucleotide-directed mutation construction

1984 • 511 citations

DNA structural variations in the E. coli tyrT promoter

1984 • 448 citations

The unusual conformation adopted by the adenine tracts in kinetoplast DNA

1987 • 321 citations

A simple procedure for resolution of Escherichia coli RNA polymerase holoenzyme from core polymerase

1977 • 297 citations

The interaction of RNA polymerase and lac repressor with the lac control region

1979 • 283 citations

RNA polymerase and the regulation of transcription

1987 • 256 citations

Mechanism of CRP-cAMP activation of lac operon transcription initiation activation of the P1 promoter

1984 • 228 citations

Construction and analysis of in vivo activity of E. coll promoter hybrids and promoter mutants that alter the −35 to −10 spacing

1982 • 219 citations

Evidence from base-pair kinetics for two types of adenine tract structures in solution: their relation to DNA curvature

1988 • 179 citations

Mapping of single-stranded regions in duplex DNA at the sequence level: single-strand-specific cytosine methylation in RNA polymerase-promoter complexes.

1983 • 164 citations

Structural details of an adenine tract that does not cause DNA to bend

1988 • 159 citations

Three promoters near the termini of IS10: pIN, pOUT, and pIII

1983 • 142 citations

A premelting conformational transition in poly(dA)-poly(dT) coupled to daunomycin binding

1989 • 134 citations

High-copy-number derivatives of the plasmid cloning vector pBR322

1984 • 93 citations

Methods of DNA and RNA sequencing

1983 • 92 citations

Regulation of the kinetics of the interaction of Escherichia coli RNA polymerase with the .lambda.PR promoter by salt concentration

1985 • 88 citations

Lac UV5 transcription in vitro. Rate limitation subsequent to formation of an RNA polymerase-DNA complex

1979 • 56 citations

The structure of poly(dA):poly(dT) in a condensed state and in solution

1987 • 48 citations

Nucleotide sequence determination of a strong promoter of the colicin E 1 plasmid. Analysis of restriction sites protected by RNA polymerase interactions before and after limited transcription

1979 • 33 citations

A general method to select for M13 clones carrying base pair substitution mutants constructedin vitro

1983 • 24 citations

Chromogenic identification of oligonucleotide-directed mutants

1986 • 12 citations

Site-directed chemical modification for probing DNA-protein interactions

1989 • 8 citations