Binding mode of novel 1-substituted quinazoline derivatives to poly(ADP-ribose) polymerase-catalytic domain, revealed by X-ray crystal structure analysis of complexes

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

1999 • 1,753 citations

The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors

2002 • 1,352 citations

The finer things in X-ray diffraction data collection

1999 • 1,242 citations

Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells

1997 • 1,034 citations

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

1997 • 1,020 citations

Poly(ADP-ribose) polymerase: a molecular nick-sensor

1994 • 790 citations

Role of poly(ADP-ribose) synthetase in inflammation and ischaemia–reperfusion

1998 • 687 citations

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

1999 • 597 citations

Structure of the catalytic fragment of poly(AD-ribose) polymerase from chicken.

1996 • 234 citations

Poly(ADP-ribose) polymerase is a catalytic dimer and the automodification reaction is intermolecular.

1993 • 222 citations

Inhibitor and NAD⁺ Binding to Poly(ADP-ribose) Polymerase As Derived from Crystal Structures and Homology Modeling^,

1998 • 196 citations

Histone shuttling by poly ADP-ribosylation

1994 • 173 citations

Dual Function for Poly(ADP-ribose) Synthesis in Response to DNA Strand Breakage

1994 • 168 citations

The mechanism of the elongation and branching reaction of Poly(ADP-ribose) polymerase as derived from crystal structures and mutagenesis

1998 • 160 citations

Histone shuttling by poly(ADP-ribosylation).

1992 • 152 citations

Invertebrate cell system applications

1989 • 144 citations

Potentiation of temozolomide-induced cytotoxicity: a comparative study of the biological effects of poly(ADP-ribose) polymerase inhibitors

1995 • 131 citations

Invertebrate Cell System Applications: Volume II

1989 • 124 citations

Dihydroisoquinolinones: the design and synthesis of a new series of potent inhibitors of poly(ADP-ribose) polymerase.

1991 • 113 citations

Efficient protein production using a Bombyx mori nuclear polyhedrosis virus lacking the cysteine proteinase gene.

1997 • 109 citations

Inhibitor‐induced structural change of the active site of human poly(ADP‐ribose) polymerase

2003 • 84 citations

Neuronal accumulation of poly(ADP‐ribose) after brain ischaemia

1999 • 74 citations

The carboxyl-terminal domain of human poly(ADP-ribose) polymerase. Overproduction in Escherichia coli, large scale purification, and characterization

1993 • 64 citations

Inhibitors and activators of ADP-ribosylation reactions

1994 • 56 citations

GPI 6150 Prevents H2O2 Cytotoxicity by Inhibiting Poly(ADP-ribose) Polymerase

2000 • 45 citations

Transient formation of DNA strand breaks during the induced differentiation of a human promyelocytic leukaemic cell line, HL-60

1987 • 41 citations

Biochemical Characterization of Mono(ADP-ribosyl)ated Poly(ADP-ribose) Polymerase

1999 • 36 citations

Crystallization and X-ray Crystallogragphic Analysis of Recombinant Chicken Poly (ADP-ribose) Polymerase Catalytic Domain Produced in Sf9 Insect Cells

1994 • 26 citations

The 40 kDa Carboxy-terminal Domain of Poly(ADP-ribose) Polymerase-1 Forms Catalytically Competent Homo- and Heterodimers in the Absence of DNA

2003 • 25 citations