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Structure of DNA Polymerase β with the Mutagenic DNA Lesion 8-Oxodeoxyguanine Reveals Structural Insights into Its Coding Potential

Data up to Jan 2025

Published2003
Citations137
References45

Total Citations Per Year

Abstract

References (45)

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

[26] Raster3D: Photorealistic molecular graphics

1997 • 3,784 citations

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

1991 • 2,172 citations

Structure of a Covalently Trapped Catalytic Complex of HIV-1 Reverse Transcriptase: Implications for Drug Resistance

1998 • 1,420 citations

Structure of a B-DNA dodecamer: conformation and dynamics.

1981 • 1,394 citations

Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution

1998 • 1,164 citations

Structure of a B-DNA dodecamer

1981 • 908 citations

Structure of a B-DNA dodecamer

1981 • 891 citations

Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

1985 • 855 citations

Mutagenesis by 8-oxoguanine: an enemy within

1993 • 805 citations

Endogenous mutagens and the causes of aging and cancer

1991 • 725 citations

Efficient Bypass of a Thymine-Thymine Dimer by Yeast DNA Polymerase, Polη

1999 • 719 citations

Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP.

1994 • 694 citations

Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation

1998 • 682 citations

Crystal Structures of Human DNA Polymerase β Complexed with Gapped and Nicked DNA: Evidence for an Induced Fit Mechanism,

1997 • 601 citations

Structures of Ternary Complexes of Rat DNA Polymerase β, a DNA Template-Primer, and ddCTP

1994 • 587 citations

Structure of the Replicating Complex of a Pol α Family DNA Polymerase

2001 • 536 citations

Fidelity of Human DNA Polymerase η

2000 • 395 citations

Low fidelity DNA synthesis by human DNA polymerase-η

2000 • 362 citations

Structure of the Catalytic Core of S. cerevisiae DNA Polymerase η

2001 • 341 citations

Efficient and accurate replication in the presence of 7,8-dihydro-8-oxoguanine by DNA polymerase η

2000 • 340 citations

NMR structural studies of the ionizing radiation adduct 7-hydro-8-oxodeoxyguanosine (8-oxo-7H-dG) opposite deoxyadenosine in a DNA duplex. 8-Oxo-7H-dG(syn).cntdot.dA(anti) alignment at lesion site

1991 • 295 citations

Crystal Structure of a DNA Duplex Containing 8-Hydroxydeoxyguanine-Adenine Base Pairs

1994 • 225 citations

X-ray structure of a DNA decamer containing 7,8-dihydro-8-oxoguanine.

1995 • 212 citations

NMR studies of a DNA containing 8-hydroxydeoxyguanosine

1991 • 209 citations

Enzyme-DNA Interactions Required for Efficient Nucleotide Incorporation and Discrimination in Human DNA Polymerase β

1996 • 165 citations

Carbon-13 magnetic resonance spectra of 8-substituted purine nucleosides. Characteristic shifts for the syn conformation

1977 • 158 citations

[11] Purification and domain-mapping of mammalian DNA polymerase β

1995 • 157 citations

DNA Structure and Aspartate 276 Influence Nucleotide Binding to Human DNA Polymerase β

2001 • 151 citations

Structural and conformational analyses of 8-hydroxy-2'-deoxyguanosine

1989 • 147 citations

Structural design of a eukaryotic DNA repair polymerase: DNA polymerase β

2000 • 144 citations

Unique misinsertion specificity of poliota may decrease the mutagenic potential of deaminated cytosines

2001 • 117 citations

8-OxodGTP Incorporation by DNA Polymerase β Is Modified by Active-Site Residue Asn279

2000 • 106 citations

Analysis of Nucleotide Insertion and Extension at 8-Oxo-7,8-dihydroguanine by Replicative T7 Polymerase exo- and Human Immunodeficiency Virus-1 Reverse Transcriptase Using Steady-State and Pre-Steady-State Kinetics

1997 • 102 citations

Structural and thermodynamic studies on the adenine.guanine mismatch in B-DNA

1990 • 92 citations

Polymerase β simulations suggest that Arg258 rotation is a slow step rather than large subdomain motions per se 1 1Edited by B. Honig

2002 • 89 citations

Translesional synthesis on DNA templates containing 8-oxo-7,8-dihydrodeoxyadenosine

1993 • 81 citations

Loss of DNA Polymerase β Stacking Interactions with Templating Purines, but Not Pyrimidines, Alters Catalytic Efficiency and Fidelity

2002 • 73 citations

Single 8-oxo-guanine and 8-oxo-adenine lesions induce marked changes in the backbone structure of a 25-base DNA strand

2000 • 61 citations

Minor Groove Interactions at the DNA Polymerase β Active Site Modulate Single-base Deletion Error Rates

2000 • 53 citations

An Improved Method for The Preparation Of The Phosphoramidites Of Modified 2′-Deoxynucleotides: Incorporation Of 8-Oxo-2′-Deoxy-7<u>H</u>-Guanosine Into Synthetic Oligomers

1991 • 38 citations

DNA Lesion Bypass Polymerases Open Up

2001 • 25 citations

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Structure of DNA Polymerase β with the Mutagenic DNA Lesion 8-Oxodeoxyguanine Reveals… (2003) – Structure | Metascience Observatory Explorer