Efficient and accurate replication in the presence of 7,8-dihydro-8-oxoguanine by DNA polymerase η

Oxidants, antioxidants, and the degenerative diseases of aging.

1993 • 6,011 citations

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

1991 • 2,172 citations

The distribution of the numbers of mutants in bacterial populations

1949 • 1,471 citations

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η

1999 • 1,273 citations

Oxidative Decay of DNA

1997 • 938 citations

A Method for Gene Disruption That Allows Repeated Use of URA3 Selection in the Construction of Multiply Disrupted Yeast Strains

1987 • 887 citations

hRAD30 Mutations in the Variant Form of Xeroderma Pigmentosum

1999 • 724 citations

Efficient Bypass of a Thymine-Thymine Dimer by Yeast DNA Polymerase, Polη

1999 • 719 citations

DNA oxidation matters: The HPLC–electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine

1998 • 694 citations

Biochemical Basis of DNA Replication Fidelity

1993 • 441 citations

Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted G.C-->T.A transversions in simian kidney cells.

1993 • 407 citations

Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase.

1990 • 293 citations

MSH2 and MSH6 Are Required for Removal of Adenine Misincorporated Opposite 8-Oxo-Guanine in S. cerevisiae

1999 • 230 citations

[19] Gel fidelity assay measuring nucleotide misinsertion, exonucleolytic proofreading, and lesion bypass efficiencies

1995 • 225 citations

Inactivation of OGG1 increases the incidence of G · C→T · A transversions in Saccharomyces cerevisiae : evidence for endogenous oxidative damage to DNA in eukaryotic cells

1997 • 217 citations

Fidelity and Processivity of Saccharomyces cerevisiae DNA Polymerase η

1999 • 179 citations

Requirement of Mismatch Repair Genes MSH2 and MSH3 in the RAD1-RAD10 Pathway of Mitotic Recombination in Saccharomyces cerevisiae

1996 • 131 citations

Requirement of DNA Polymerase Activity of Yeast Rad30 Protein for Its Biological Function

1999 • 105 citations

“Action-at-a-Distance” Mutagenesis

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1978 • 14 citations