Taurine Is a Potent Activator of Extrasynaptic GABA_AReceptors in the Thalamus

Physiological actions of taurine

1992 • 2,555 citations

Variations on an inhibitory theme: phasic and tonic activation of GABAA receptors

2005 • 1,983 citations

GABAA receptors: immunocytochemical distribution of 13 subunits in the adult rat brain

2000 • 1,322 citations

Electrophysiological properties of guinea‐pig thalamic neurones: an in vitro study.

1984 • 1,316 citations

Subunit Composition, Distribution and Function of GABA-A Receptor Subtypes

2002 • 889 citations

THE EXCITATION AND DEPRESSION OF SPINAL NEURONES BY STRUCTURALLY RELATED AMINO ACIDS

1960 • 853 citations

Low-Threshold Calcium Currents in Central Nervous System Neurons

1996 • 757 citations

Selective changes in single cell GABAA receptor subunit expression and function in temporal lobe epilepsy

1998 • 741 citations

Tonically active GABAA receptors: modulating gain and maintaining the tone

2004 • 730 citations

Development of a tonic form of synaptic inhibition in rat cerebellar granule cells resulting from persistent activation of GABAA receptors.

1996 • 724 citations

Ovarian cycle–linked changes in GABAA receptors mediating tonic inhibition alter seizure susceptibility and anxiety

2005 • 624 citations

GABA TRANSPORTER HETEROGENEITY: PHARMACOLOGY AND CELLULAR LOCALIZATION

1996 • 582 citations

Selective Modulation of Tonic and Phasic Inhibitions in Dentate Gyrus Granule Cells

2002 • 491 citations

Ethanol enhances α ₄ β ₃ δ and α ₆ β ₃ δ γ-aminobutyric acid type A receptors at low concentrations known to affect humans

2003 • 462 citations

In vivo determination of extracellular concentration of amino acids in the rat hippocampus. A method based on brain dialysis and computerized analysis

1986 • 428 citations

Molecular characterization of four pharmacologically distinct gamma-aminobutyric acid transporters in mouse brain [corrected].

1993 • 415 citations

Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+

1990 • 370 citations

GABRD encoding a protein for extra- or peri-synaptic GABAA receptors is a susceptibility locus for generalized epilepsies

2004 • 348 citations

Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1

1994 • 338 citations

Hormonally regulated α4β2δ GABAA receptors are a target for alcohol

2002 • 331 citations

Withdrawal from Chronic Intermittent Ethanol Treatment Changes Subunit Composition, Reduces Synaptic Function, and Decreases Behavioral Responses to Positive Allosteric Modulators of GABA_AReceptors

2003 • 327 citations

Altered Expression of the δ Subunit of the GABA_AReceptor in a Mouse Model of Temporal Lobe Epilepsy

2004 • 318 citations

Alcohol-induced motor impairment caused by increased extrasynaptic GABAA receptor activity

2005 • 308 citations

GABA _A receptor α4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol

2006 • 305 citations

GABA_AReceptor-Mediated Tonic Inhibition in Thalamic Neurons

2005 • 299 citations

A new naturally occurring GABAA receptor subunit partnership with high sensitivity to ethanol

2006 • 254 citations

Extrasynaptic GABA_AReceptors of Thalamocortical Neurons: A Molecular Target for Hypnotics

2005 • 247 citations

Low Ethanol Concentrations Selectively Augment the Tonic Inhibition Mediated by δ Subunit-Containing GABA_AReceptors in Hippocampal Neurons

2004 • 246 citations

An Extrasynaptic GABA_A Receptor Mediates Tonic Inhibition in Thalamic VB Neurons

2005 • 238 citations

Taurine prevents the neurotoxicity of β‐amyloid and glutamate receptor agonists: activation of GABA receptors and possible implications for Alzheimer's disease and other neurological disorders

2004 • 229 citations

GABA_A receptors are differentially sensitive to zinc: dependence on subunit composition

1991 • 223 citations

Agonist action of taurine on glycine receptors in rat supraoptic magnocellular neurones: possible role in osmoregulation

1997 • 214 citations

Pharmacological Characterization of Agonists at δ-Containing GABA_AReceptors: Functional Selectivity for Extrasynaptic Receptors Is Dependent on the Absence of γ₂

2005 • 209 citations

Neurosteroids Shift Partial Agonist Activation of GABA_AReceptor Channels from Low- to High-Efficacy Gating Patterns

2003 • 207 citations

Taurine Interaction with Neurotransmitter Receptors in the CNS: An Update

2005 • 196 citations

GAT2/BGT-1 as a System Responsible for the Transport of γ-Aminobutyric Acid at the Mouse Blood–Brain Barrier

2001 • 167 citations

Chronic Intermittent Ethanol-Induced Switch of Ethanol Actions from Extrasynaptic to Synaptic Hippocampal GABA_AReceptors

2006 • 158 citations

Functional Correlation of GABA_AReceptor α Subunits Expression with the Properties of IPSCs in the Developing Thalamus

2000 • 149 citations

Taurine activates GABAA but not GABAB receptors in rat hippocampal CA1 area

2000 • 128 citations

Intact Synaptic GABAergic Inhibition and Altered Neurosteroid Modulation of Thalamic Relay Neurons in Mice Lacking δ Subunit

2003 • 112 citations

Osmoregulation of Vasopressin Secretion via Activation of Neurohypophysial Nerve Terminals Glycine Receptors by Glial Taurine

2001 • 112 citations

Taurine acts on a subclass of GABAa receptors in mammalian brain in vitro

1991 • 109 citations

Endogenous Amino Acid Release from Cultured Cerebellar Neuronal Cells: Effect of Tetanus Toxin on Glutamate Release

1989 • 109 citations

Cloning of the human homologue of the GABA transporter GAT-3 and identification of a novel inhibitor with selectivity for this site.

1994 • 109 citations

Taurine Levels in Discrete Brain Nuclei of Rats

1986 • 103 citations

GABA_A Receptor-Mediated Cl⁻ Currents in Rat Thalamic Reticular and Relay Neurons

1997 • 95 citations

Taurine Analogues; A New Class of Therapeutics: Retrospect and Prospects

2005 • 89 citations

Nucleus-Specific Differences in GABA_A-Receptor-Mediated Inhibition Are Enhanced During Thalamic Development

2000 • 75 citations

Modulation of taurine release by glutamate receptors and nitric oxide

2000 • 69 citations

Characterization of strychnine-sensitive glycine receptors in acutely isolated adult rat basolateral amygdala neurons

2000 • 65 citations

Pharmacological characterization of volume‐sensitive, taurine permeable anion channels in rat supraoptic glial cells

2000 • 61 citations

Taurine Activates Strychnine-Sensitive Glycine Receptors in Neurons Freshly Isolated From Nucleus Accumbens of Young Rats

2004 • 58 citations

Rat α₆β₂δ GABA_A receptors exhibit two distinct and separable agonist affinities

2007 • 56 citations

Potassium‐Stimulated Release of [³HJTaurine from Cultured GABAergic and Glutamatergic Neurons

1989 • 53 citations

Characteristics of ischemia-induced taurine release in the developing mouse hippocampus

1999 • 52 citations

Looking for GABA in all the Wrong Places: The Relevance of Extrasynaptic GABA_A Receptors to Epilepsy

2004 • 50 citations

Visual acuity loss ion rhesus monkey infants fed a taurine‐free human infant formula

1987 • 46 citations

Release of taurine from cultured cerebellar granule cells and astrocytes: co-release with glutamate

1989 • 38 citations

K+-evoked taurine efflux from cerebellar astrocytes: On the roles of Ca2+ and Na+

1989 • 34 citations

Taurine-evoked chloride current and its potentiation by intracellular Ca2+ in immature rat hippocampal CA1 neurons

2003 • 34 citations

Glycinergic inhibition in thalamus revealed by synaptic receptor blockade

2005 • 33 citations

Taurine activates strychnine-sensitive glycine receptors in neurons of the rat inferior colliculus

2004 • 24 citations

Abnormal Visual Acuity and Retinal Morphology in Rhesus Monkeys Fed a Taurine-Free Diet During the First Three Postnatal Months

1987 • 22 citations

L‐glutamate‐stimulated taurine release from rat cerebral cultured astrocytes

1994 • 17 citations

Distinctive Glycinergic Currents With Fast and Slow Kinetics in Thalamus

2006 • 15 citations