Pharmacological Characterization of Agonists at δ-Containing GABA_AReceptors: Functional Selectivity for Extrasynaptic Receptors Is Dependent on the Absence of γ₂

Subunit Composition, Distribution and Function of GABA-A Receptor Subtypes

2002 • 889 citations

Segregation of Different GABA_AReceptors to Synaptic and Extrasynaptic Membranes of Cerebellar Granule Cells

1998 • 829 citations

Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by δ subunit-containing GABA _A receptors

2003 • 785 citations

Pharmacological characterization of a novel cell line expressing human α₄β₃δ GABA_A receptors

2002 • 607 citations

Adaptive regulation of neuronal excitability by a voltage- independent potassium conductance

2001 • 582 citations

Ethanol enhances α ₄ β ₃ δ and α ₆ β ₃ δ γ-aminobutyric acid type A receptors at low concentrations known to affect humans

2003 • 462 citations

Perisynaptic localization of delta subunit-containing GABA(A) receptors and their activation by GABA spillover in the mouse dentate gyrus.

2003 • 399 citations

Distinct Functional and Pharmacological Properties of Tonic and Quantal Inhibitory Postsynaptic Currents Mediated by γ-Aminobutyric Acid_A Receptors in Hippocampal Neurons

2001 • 363 citations

Perisynaptic Localization of δ Subunit-Containing GABA_AReceptors and Their Activation by GABA Spillover in the Mouse Dentate Gyrus

2003 • 348 citations

Assembly of GABAA receptor subunits: role of the delta subunit

1994 • 335 citations

Hormonally regulated α4β2δ GABAA receptors are a target for alcohol

2002 • 331 citations

Ligand-gated ion channel subunit partnerships: GABAA receptor alpha6 subunit gene inactivation inhibits delta subunit expression.

1997 • 322 citations

Ligand-Gated Ion Channel Subunit Partnerships: GABA_AReceptor α₆Subunit Gene Inactivation Inhibits δ Subunit Expression

1997 • 290 citations

Distinguishing between GABA(A) receptors responsible for tonic and phasic conductances.

2001 • 261 citations

Functional characterization of human gamma-aminobutyric acidA receptors containing the alpha 4 subunit.

1996 • 259 citations

GABA_A receptor changes in δ subunit‐deficient mice: Altered expression of α4 and γ2 subunits in the forebrain

2002 • 247 citations

Preferential Coassembly of α4 and δ Subunits of the γ-Aminobutyric Acid_AReceptor in Rat Thalamus

1999 • 226 citations

GABA_A receptors are differentially sensitive to zinc: dependence on subunit composition

1991 • 223 citations

α4β3δ GABAAReceptors Characterized by Fluorescence Resonance Energy Transfer-derived Measurements of Membrane Potential

2001 • 196 citations

Role of the beta subunit in determining the pharmacology of human gamma-aminobutyric acid type A receptors.

1993 • 194 citations

Subunit composition and quantitative importance of hetero-oligomeric receptors: GABAA receptors containing alpha6 subunits.

1998 • 193 citations

Gene Knockout of the α6 Subunit of the γ-Aminobutyric Acid Type A Receptor: Lack of Effect on Responses to Ethanol, Pentobarbital, and General Anesthetics

1997 • 180 citations

Subunit Composition and Quantitative Importance of Hetero-oligomeric Receptors: GABA_AReceptors Containing α₆Subunits

1998 • 175 citations

Molecular pharmacology of gamma-aminobutyric acid type A receptor agonists and partial agonists in oocytes injected with different alpha, beta, and gamma receptor subunit combinations.

1994 • 172 citations

Colocalization of multiple GABAA receptor subtypes with gephyrin at postsynaptic sites

2000 • 172 citations

Short-term steroid treatment increases δ GABAA receptor subunit expression in rat CA1 hippocampus: Pharmacological and behavioral effects

2005 • 157 citations

The GABA A agonist THIP produces slow wave sleep and reduces spindling activity in NREM sleep in humans

1997 • 145 citations

Differences in Agonist/Antagonist Binding Affinity and Receptor Transduction Using Recombinant Human γ-Aminobutyric Acid Type A Receptors

1997 • 145 citations

Altered Pharmacology of Synaptic and Extrasynaptic GABA_AReceptors on CA1 Hippocampal Neurons Is Consistent with Subunit Changes in a Model of Alcohol Withdrawal and Dependence

2004 • 133 citations

Distribution of α1, α4, γ2, and δ subunits of GABAA receptors in hippocampal granule cells

2004 • 125 citations

Alterations in the expression of GABA_A receptor subunits in cerebellar granule cells after the disruption of the α6 subunit gene

1999 • 112 citations

Cloning of cDNAs encoding the human gamma-aminobutyric acid type A receptor alpha 6 subunit and characterization of the pharmacology of alpha 6-containing receptors.

1996 • 91 citations

Identification of a Zn²⁺ binding site on the marine gABA_A receptor complex: Dependence on the Second transmembrane domain of β subunits

1997 • 74 citations

LIGAND-GATED ION CHANNEL SUBUNIT PARTNERSHIPS: GABAA RECEPTOR α6 SUBUNIT GENE INACTIVATION INHIBITS δ SUBUNIT EXPRESSION

1997 • 73 citations

Discriminative stimulus effects of atypical anxiolytics in baboons and rats.

1986 • 68 citations

Rotarod studies in the rat of the GABAA receptor agonist gaboxadol: lack of ethanol potentiation and benzodiazepine cross-tolerance

2003 • 43 citations

Gaboxadol: in vitro interaction studies with benzodiazepines and ethanol suggest functional selectivity

2003 • 41 citations

Characterization of GABA_A receptor ligands in the rat cortical wedge preparation: evidence for action at extrasynaptic receptors?

2002 • 31 citations

Two γ2L subunit domains confer low Zn²⁺ sensitivity to ternary GABA_A receptors

2001 • 30 citations

Bioisosteric determinants for subtype selectivity of ligands for heteromeric GABAA receptors

2001 • 28 citations

Pharmacokinetics of the γ‐Aminobutyric Acid Agonist THIP (Gaboxadol) Following Intramuscular Administration to Man, with Observations in Dog

1983 • 23 citations

Discriminative stimulus effects of zolpidem in squirrel monkeys: comparison with conventional benzodiazepines and sedative-hypnotics.

1999 • 20 citations

Muscimol-Like Discriminative Stimulus Effects of GABA Agonists in Rats

1998 • 17 citations

Comparison of some properties of pronethalol and propranolol

1997 • 7 citations