Extrasynaptic GABA_AReceptors of Thalamocortical Neurons: A Molecular Target for Hypnotics

Variations on an inhibitory theme: phasic and tonic activation of GABAA receptors

2005 • 1,983 citations

GABAA receptors: immunocytochemical distribution of 13 subunits in the adult rat brain

2000 • 1,322 citations

Neurosteroids: endogenous regulators of the GABAA receptor

2005 • 1,083 citations

On The Cellular and Network Bases of Epileptic Seizures

2001 • 1,018 citations

Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by δ subunit-containing GABA _A receptors

2003 • 785 citations

Molecular and neuronal substrates for general anaesthetics

2004 • 750 citations

Development of a tonic form of synaptic inhibition in rat cerebellar granule cells resulting from persistent activation of GABAA receptors.

1996 • 724 citations

Ovarian cycle–linked changes in GABAA receptors mediating tonic inhibition alter seizure susceptibility and anxiety

2005 • 624 citations

Pharmacological characterization of a novel cell line expressing human α₄β₃δ GABA_A receptors

2002 • 607 citations

Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by α5 subunit-containing γ-aminobutyric acid type A receptors

2004 • 559 citations

Selective Modulation of Tonic and Phasic Inhibitions in Dentate Gyrus Granule Cells

2002 • 491 citations

Brain Mechanisms of Propofol-Induced Loss of Consciousness in Humans: a Positron Emission Tomographic Study

1999 • 482 citations

The corticothalamic system in sleep

2003 • 482 citations

Network modulation of a slow intrinsic oscillation of cat thalamocortical neurons implicated in sleep delta waves: cortically induced synchronization and brainstem cholinergic suppression

1991 • 479 citations

Ethanol enhances α ₄ β ₃ δ and α ₆ β ₃ δ γ-aminobutyric acid type A receptors at low concentrations known to affect humans

2003 • 462 citations

Sleep, epilepsy and thalamic reticular inhibitory neurons

2005 • 437 citations

Toward a Unified Theory of Narcosis: Brain Imaging Evidence for a Thalamocortical Switch as the Neurophysiologic Basis of Anesthetic-Induced Unconsciousness

2000 • 390 citations

The interaction of the general anesthetic etomidate with the γ-aminobutyric acid type A receptor is influenced by a single amino acid

1997 • 382 citations

Reciprocal Inhibitory Connections and Network Synchrony in the Mammalian Thalamus

1999 • 364 citations

Thalamic circuitry and thalamocortical synchrony

2002 • 331 citations

Receptors with Different Affinities Mediate Phasic and Tonic GABA_AConductances in Hippocampal Neurons

2002 • 330 citations

Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms.

2003 • 290 citations

Sedation and Anesthesia Mediated by Distinct GABA_AReceptor Isoforms

2003 • 247 citations

Low Ethanol Concentrations Selectively Augment the Tonic Inhibition Mediated by δ Subunit-Containing GABA_AReceptors in Hippocampal Neurons

2004 • 246 citations

Effect of benzodiazepine hypnotics on all-night sleep EEG spectra.

1985 • 235 citations

Loss of the Major GABA_AReceptor Subtype in the Brain Is Not Lethal in Mice

2001 • 235 citations

Subunit‐dependent interaction of the general anaesthetic etomidate with the γ‐aminobutyric acid type A receptor

1997 • 234 citations

Diazepam-induced changes in sleep: Role of the α1 GABA_Areceptor subtype

2001 • 227 citations

General anaesthetic action at transmitter-gated inhibitory amino acid receptors

1999 • 137 citations

Modulation of rhythmic brain activity by diazepam: GABA _A receptor subtype and state specificity

2004 • 129 citations

The Contraceptive Agent Provera Enhances GABA_AReceptor-Mediated Inhibitory Neurotransmission in the Rat Hippocampus: Evidence for Endogenous Neurosteroids?

2003 • 127 citations

GABAA agonists and partial agonists: THIP (Gaboxadol) as a non-opioid analgesic and a novel type of hypnotic

2004 • 125 citations

Role of GABAA Receptors in Sleep Regulation Differential Effects of Muscimol and Midazolam on Sleep in Rats

1996 • 113 citations

Intact Synaptic GABAergic Inhibition and Altered Neurosteroid Modulation of Thalamic Relay Neurons in Mice Lacking δ Subunit

2003 • 112 citations

Dynamic GABA_AReceptor Subtype-Specific Modulation of the Synchrony and Duration of Thalamic Oscillations

2003 • 92 citations

Chemokine production by human vascular smooth muscle cells: modulation by IL‐13

1997 • 92 citations

Three types of inhibitory postsynaptic potentials generated by interneurons in the anterior thalamic complex of cat

1991 • 88 citations

The GABAA agonist THIP (gaboxadol) increases non-REM sleep and enhances delta activity in the rat

1996 • 78 citations

Nucleus-Specific Differences in GABA_A-Receptor-Mediated Inhibition Are Enhanced During Thalamic Development

2000 • 75 citations

Diazepam‐induced changes on sleep and the EEG spectrum in mice: role of the α3‐GABA_A receptor subtype

2003 • 70 citations

Sleep and Its Modulation by Drugs That Affect GABAA Receptor Function

1999 • 57 citations

Neural Mechanisms of Anesthesia

2002 • 53 citations

Sleep states and sleep electroencephalographic spectral power in mice lacking the β3 subunit of the GABAA receptor

2002 • 47 citations

The GABAA receptor agonist THIP alters the EEG in waking and sleep of mice

2005 • 44 citations

Pharmacokinetics of the γ‐Aminobutyric Acid Agonist THIP (Gaboxadol) Following Intramuscular Administration to Man, with Observations in Dog

1983 • 23 citations

Sleep and Anesthesia

2003 • 4 citations