Ethanol enhances α ₄ β ₃ δ and α ₆ β ₃ δ γ-aminobutyric acid type A receptors at low concentrations known to affect humans

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1989 • 1,456 citations

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Segregation of Different GABA_AReceptors to Synaptic and Extrasynaptic Membranes of Cerebellar Granule Cells

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1994 • 622 citations

Pharmacological characterization of a novel cell line expressing human α₄β₃δ GABA_A receptors

2002 • 607 citations

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2001 • 582 citations

General anesthetic actionsin vivostrongly attenuated by a point mutation in the GABA_Areceptor β3 subunit

2002 • 555 citations

Ethanol stimulates gamma-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes.

1986 • 543 citations

Attenuated sensitivity to neuroactive steroids in γ-aminobutyrate type A receptor delta subunit knockout mice

1999 • 522 citations

Selective Modulation of Tonic and Phasic Inhibitions in Dentate Gyrus Granule Cells

2002 • 491 citations

Enhanced Neurosteroid Potentiation of Ternary GABA_AReceptors Containing the δ Subunit

2002 • 388 citations

The interaction of the general anesthetic etomidate with the γ-aminobutyric acid type A receptor is influenced by a single amino acid

1997 • 382 citations

Ethanol increases GABAergic transmission at both pre- and postsynaptic sites in rat central amygdala neurons

2003 • 347 citations

Assembly of GABAA receptor subunits: role of the delta subunit

1994 • 335 citations

Hormonally regulated α4β2δ GABAA receptors are a target for alcohol

2002 • 331 citations

The influence of subunit composition on the interaction of neurosteroids with GABAA receptors

2002 • 329 citations

Withdrawal from Chronic Intermittent Ethanol Treatment Changes Subunit Composition, Reduces Synaptic Function, and Decreases Behavioral Responses to Positive Allosteric Modulators of GABA_AReceptors

2003 • 327 citations

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1997 • 322 citations

Ligand-Gated Ion Channel Subunit Partnerships: GABA_AReceptor α₆Subunit Gene Inactivation Inhibits δ Subunit Expression

1997 • 290 citations

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2003 • 290 citations

Ethanol potentiation of GABAergic transmission in cultured spinal cord neurons involves gamma-aminobutyric acidA-gated chloride channels.

1988 • 278 citations

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2001 • 261 citations

Functional characterization of human gamma-aminobutyric acidA receptors containing the alpha 4 subunit.

1996 • 259 citations

Pharmacology of neuronal background potassium channels

2003 • 256 citations

Ethanol opens G-protein-activated inwardly rectifying K+ channels

1999 • 253 citations

The TASK-1 Two-Pore Domain K⁺ Channel Is a Molecular Substrate for Neuronal Effects of Inhalation Anesthetics

2000 • 251 citations

Sedation and Anesthesia Mediated by Distinct GABA_AReceptor Isoforms

2003 • 247 citations

GABA_A receptor changes in δ subunit‐deficient mice: Altered expression of α4 and γ2 subunits in the forebrain

2002 • 247 citations

G-protein-coupled inwardly rectifying potassium channels are targets of alcohol action

1999 • 241 citations

Preferential Coassembly of α4 and δ Subunits of the γ-Aminobutyric Acid_AReceptor in Rat Thalamus

1999 • 226 citations

Ethanol potentiation of 5-hydroxytryptamine3 receptor-mediated ion current in neuroblastoma cells and isolated adult mammalian neurons.

1991 • 210 citations

Volatile general anaesthetics activate a novel neuronal K+ current

1988 • 199 citations

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2001 • 196 citations

Gene Knockout of the α6 Subunit of the γ-Aminobutyric Acid Type A Receptor: Lack of Effect on Responses to Ethanol, Pentobarbital, and General Anesthetics

1997 • 180 citations

GABA_A‐Receptor δ Subunit Knockout Mice Have Multiple Defects in Behavioral Responses to Ethanol

2001 • 161 citations

Anesthesia Sensitivity in Mice that Lack the β3 Subunit of the γ-Aminobutyric Acid Type A Receptor

1998 • 159 citations

Two-Pore-Domain (Kcnk) Potassium Channels: Dynamic Roles in Neuronal Function

2003 • 150 citations

Molecular determinants for the action of general anesthetics at recombinant α₂β₃γ₂γ‐aminobutyric acid_A receptors

2001 • 136 citations

Low ethanol concentrations enhance GABAergic inhibitory postsynaptic potentials in hippocampal pyramidal neurons only after block of GABAB receptors.

1996 • 136 citations

The crisis of (confidence in) global capitalism

2000 • 132 citations

Gaba in the nervous system : the view at fifty years

2000 • 120 citations

GABA-A Receptors as Molecular Sites of Ethanol Action. Direct or Indirect Actions?

2002 • 112 citations

Alcohol potently inhibits the kainate receptor-dependent excitatory drive of hippocampal interneurons

2003 • 97 citations

Anaesthetic concentrations of alcohols potentiate GABAA receptor-mediated currents: lack of subunit specificity

1994 • 86 citations

Activation and inhibition of G protein-coupled inwardly rectifying potassium (Kir3) channels by G protein βγ subunits

2000 • 81 citations

Involvement of Neuronal Chloride Channels in Ethanol Intoxication, Tolerance, and Dependence

1987 • 74 citations

The in vitro and in vivo enantioselectivity of etomidate implicates the GABAA receptor in general anaesthesia

2003 • 71 citations

Differential Effects of General Anesthetics on G Protein–coupled Inwardly Rectifying and Other Potassium Channels

2001 • 71 citations

Alcohol and Benzodiazepines in Fatal Poisonings

2002 • 60 citations

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2002 • 59 citations

Ethanol enhances gamma-aminobutyric acid responses in a subpopulation of nucleus accumbens neurons: role of metabotropic glutamate receptors.

2000 • 49 citations

G Protein-Gated Inwardly Rectifying Potassium Channels Are Targets for Volatile Anesthetics

2001 • 43 citations

Pharmacological modulation of GABA_A receptor‐mediated postsynaptic potentials in the CA1 region of the rat hippocampus

1998 • 40 citations

Conductance of GABA_A Channels Activated by Pentobarbitone in Hippocampal Neurons from Newborn Rats

2003 • 17 citations