Low-Threshold Calcium Currents in Central Nervous System Neurons

A quantitative description of membrane current and its application to conduction and excitation in nerve

1952 • 21,965 citations

Three types of neuronal calcium channel with different calcium agonist sensitivity

1985 • 2,212 citations

The action of calcium on the electrical properties of squid axons

1957 • 1,853 citations

Electrophysiological properties of guinea‐pig thalamic neurones: an in vitro study.

1984 • 1,316 citations

Kinetic and pharmacological properties distinguishing three types of calcium currents in chick sensory neurones.

1987 • 1,290 citations

Properties of a hyperpolarization‐activated cation current and its role in rhythmic oscillation in thalamic relay neurones.

1990 • 1,150 citations

Electrophysiology of mammalian inferior olivary neurones in vitro. Different types of voltage‐dependent ionic conductances.

1981 • 960 citations

Properties and distribution of ionic conductances generating electroresponsiveness of mammalian inferior olivary neurones in vitro.

1981 • 871 citations

Single‐channel recordings of three types of calcium channels in chick sensory neurones.

1987 • 563 citations

A novel T-type current underlies prolonged Ca(2+)-dependent burst firing in GABAergic neurons of rat thalamic reticular nucleus

1992 • 556 citations

Characterization of ethosuximide reduction of low‐threshold calcium current in thalamic neurons

1989 • 507 citations

Simulation of the currents involved in rhythmic oscillations in thalamic relay neurons

1992 • 493 citations

Calcium currents in rat thalamocortical relay neurones: kinetic properties of the transient, low‐threshold current.

1989 • 458 citations

Synaptic Activation of Voltage-Gated Channels in the Dendrites of Hippocampal Pyramidal Neurons

1995 • 449 citations

Kinetics and selectivity of a low‐voltage‐activated calcium current in chick and rat sensory neurones.

1987 • 420 citations

Selective increase in T-type calcium conductance of reticular thalamic neurons in a rat model of absence epilepsy

1995 • 418 citations

Two types of calcium channels in the somatic membrane of new‐born rat dorsal root ganglion neurones.

1985 • 412 citations

Amiloride Selectively Blocks the Low Threshold (T) Calcium Channel

1988 • 395 citations

Intrathalamic rhythmicity studied in vitro: nominal T-current modulation causes robust antioscillatory effects

1994 • 358 citations

Characterization of two types of calcium channels in mouse neuroblastoma cells.

1987 • 340 citations

Mechanisms of oscillatory activity in guinea‐pig nucleus reticularis thalami in vitro: a mammalian pacemaker.

1993 • 316 citations

Development of Two Types of Calcium Channels in Cultured Mammalian Hippocampal Neurons

1987 • 311 citations

A T‐type Ca2+ current underlies low‐threshold Ca2+ potentials in cells of the cat and rat lateral geniculate nucleus.

1989 • 256 citations

Specific petit mal anticonvulsants reduce calcium currents in thalamic neurons

1989 • 225 citations

Identification of two calcium currents in acutely dissociated neurons from the rat lateral geniculate nucleus

1989 • 220 citations

Thalamic bursting mechanism: an inward slow current revealed by membrane hyperpolarization

1982 • 202 citations

Activation of μ opioid receptors inhibits transient high- and low-threshold Ca 2+ currents, but spares a sustained current

1991 • 202 citations

Molecular determinants of Ca2+ channel function and drug action

1995 • 198 citations

Valproic acid selectively reduces the low-threshold (T) calcium current in rat nodose neurons

1990 • 197 citations

Properties and distribution of single voltage-gated calcium channels in adult hippocampal neurons

1990 • 178 citations

Functional Subunit Structure of Voltage-Gated Calcium Channels

1991 • 168 citations

Block of current through T‐type calcium channels by trivalent metal cations and nickel in neural rat and human cells.

1993 • 152 citations

Patch-Clamp Studies of Voltage-Gated Currents in Identified Neurons of the Rat Cerebral Cortex

1991 • 146 citations

Single low‐voltage‐activated calcium channels in chick and rat sensory neurones.

1987 • 144 citations

A G Protein Is Involved in the Angiotensin AT2 Receptor Inhibition of the T-Type Calcium Current in Non-differentiated NG108-15 Cells

1995 • 124 citations

Mechanism of gating of T-type calcium channels.

1990 • 122 citations

Calcium antagonist effects on low-threshold (T-type) calcium current in rat isolated hippocampal CA1 pyramidal neurons.

1991 • 122 citations

Hippocampal CA1 pyramidal cells of rats have four voltage-dependent calcium conductances

1989 • 120 citations

Three types of calcium channels in the membrane of mouse sensory neurons

1988 • 116 citations

Low- and high-voltage-activated calcium currents in rat spinal dorsal horn neurons

1990 • 106 citations

T-type calcium channels: heterogeneous expression in rat sensory neurons and selective modulation by phorbol esters

1990 • 104 citations

Low-threshold transient calcium current in rat hippocampal lacunosum- moleculare interneurons: kinetics and modulation by neurotransmitters

1991 • 102 citations

High- and low-threshold calcium currents in neurons acutely isolated from rat sensorimotor cortex

1990 • 98 citations

The effectiveness of different isomers of octanol as blockers of harmaline-induced tremor

1989 • 96 citations

Halothane inhibits two components of calcium current in clonal (GH3) pituitary cells

1991 • 95 citations

Protein kinase activator 1-oleoyl-2-acetyl-sn-glycerol inhibits two types of calcium currents in GH3 cells

1988 • 84 citations

Electrophysiological properties of neurons in the lateral habenula nucleus: an in vitro study

1988 • 80 citations

Calcium channels in solitary retinal ganglion cells from post‐natal rat.

1989 • 80 citations

Temperature sensitivity of Ca currents in chick sensory neurones

1990 • 76 citations

Calcium channels in isolated rat dorsal horn neurones, including labelled spinothalamic and trigeminothalamic cells.

1989 • 74 citations

Halothane blocks low-voltage-activated calcium current in rat sensory neurons

1991 • 72 citations

Single calcium channels in rat and guinea‐pig hippocampal neurons.

1991 • 70 citations

Pharmacological characterization of calcium currents and synaptic transmission between thalamic neurons in vitro

1992 • 68 citations

Three types of voltage-dependent calcium current in cultured rat hippocampal neurons

1989 • 63 citations

Modulation of neuronal T-type calcium channel currents by photoactivation of intracellular guanosine 5′-0(3-thio) triphosphate

1990 • 62 citations

Multiple components of calcium current in acutely dissociated dentate gyrus granule neurons

1994 • 61 citations

Contribution of the low-threshold T-type calcium current in generating the post-spike depolarizing afterpotential in dentate granule neurons of immature rats

1993 • 57 citations

Single-channel properties of four calcium channel types in rat motoneurons

1995 • 55 citations

Multiple types of calcium channels in acutely isolated rat neostriatal neurons

1993 • 54 citations

Low-threshold calcium current in isolated Purkinje cell bodies of rat cerebellum

1990 • 52 citations

Transient Ca2+ currents in neurons isolated from rat lateral habenula

1993 • 49 citations

Transient enhancement of low-threshold calcium current in thalamic relay neurons after corticectomy

1993 • 42 citations

Whole-cell and single-channel calcium currents in guinea pig basal forebrain neurons

1994 • 42 citations

Differential expression of voltage-gated calcium channels in identified visual cortical neurons

1991 • 42 citations

Low threshold calcium spikes, intrinsic neuronal oscillation and rhythm generation in the CNS

1989 • 40 citations

Ionic currents in cultured rat hypothalamic neurones.

1992 • 39 citations

U-92032, a T-type Ca2+ channel blocker and antioxidant, reduces neuronal ischemic injuries

1994 • 34 citations

Voltage-activated calcium channels in rat Purkinje cells maintained in culture

1989 • 25 citations

Mechanism of Block of Thalamic T-Type Ca2+ Channels by Petit Mal Anticonvulsants

1991 • 7 citations