Finding the genes in genomic DNA

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1997 • 71,835 citations

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

A tutorial on hidden Markov models and selected applications in speech recognition

1989 • 22,242 citations

tRNAscan-SE: A Program for Improved Detection of Transfer RNA Genes in Genomic Sequence

1997 • 9,993 citations

Prediction of complete gene structures in human genomic DNA

1997 • 4,041 citations

Complete Genome Sequence of the Methanogenic Archaeon, Methanococcus jannaschii

1996 • 2,043 citations

Improved Splice Site Detection in Genie

1997 • 1,490 citations

The human XIST gene: Analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus

1992 • 1,269 citations

Bacterial gene transfer by natural genetic transformation in the environment

1994 • 1,253 citations

Weight matrix descriptions of four eukaryotic RNA polymerase II promoter elements derived from 502 unrelated promoter sequences

1990 • 1,140 citations

Exon Recognition in Vertebrate Splicing

1995 • 1,067 citations

Microbial gene identification using interpolated Markov models

1998 • 1,000 citations

Interpreting cDNA sequences: Some insights from studies on translation

1996 • 785 citations

Evaluation of Gene Structure Prediction Programs

1996 • 753 citations

GENMARK: Parallel gene recognition for both DNA strands

1993 • 698 citations

The origin of interspersed repeats in the human genome

1996 • 595 citations

20 Splicing of Precursors to mRNAs by the Spliceosomes

1999 • 546 citations

Predicting Pol II Promoter Sequences using Transcription Factor Binding Sites

1995 • 446 citations

Censor—a program for identification and elimination of repetitive elements from DNA sequences

1996 • 411 citations

Assessment of protein coding measures

1992 • 404 citations

A generalized hidden Markov model for the recognition of human genes in DNA.

1996 • 393 citations

Evidence for horizontal gene transfer in Escherichia coli speciation

1991 • 386 citations

THE HUMAN GENOME: Organization and Evolutionary History

1995 • 375 citations

Predicting internal exons by oligonucleotide composition and discriminant analysis of spliceable open reading frames

1994 • 348 citations

Eukaryotic Promoter Recognition

1997 • 341 citations

A hidden Markov model that finds genes inE.coliDNA

1994 • 329 citations

Gene recognition via spliced sequence alignment.

1996 • 311 citations

Classification of Introns: U2-Type or U12-Type

1997 • 290 citations

Identification of protein coding regions in the human genome by quadratic discriminant analysis

1997 • 286 citations

What Drives Codon Choices in Human Genes?

1996 • 274 citations

Computational methods for the identification of genes in vertebrate genomic sequences

1997 • 264 citations

Finding Genes in DNA with a Hidden Markov Model

1997 • 229 citations

A Tool for Analyzing and Annotating Genomic Sequences

1997 • 227 citations

Computational methods in molecular biology

1998 • 193 citations

Architectural limits on split genes

1996 • 179 citations

Regulation of Sex-Specific Selection of fruitless 5′ Splice Sites by transformerand transformer-2

1998 • 176 citations

DNA sequence analysis of 66 kb of the human MHC class II region encoding a cluster of genes for antigen processing

1992 • 161 citations

Finding genes by computer: the state of the art

1996 • 148 citations

Prediction of Function in DNA Sequence Analysis

1995 • 139 citations

Automated Gene Identification in Large-Scale Genomic Sequences¹

1997 • 99 citations

Modeling dependencies in pre-mRNA splicing signals

1998 • 86 citations

Constructing gene models from accurately predicted exons: an application of dynamic programming

1994 • 65 citations

Base composition and gene distribution: critical patterns in mammalian genome organization

1996 • 62 citations

Las Vegas Algorithms for Gene Recognition: Suboptimal and Error-Tolerant Spliced Alignment

1997 • 26 citations

Statistical studies of biomolecular sequences: score-based methods

1994 • 19 citations

Finding genes in DNA using decision trees and dynamic programming.

1996 • 13 citations

A Segment-Based Dynamic Programming Algorithm for Predicting Gene Structure

1996 • 11 citations

FANS-REF: a bibliography on statistics and functional analysis of nucleotide sequences

1995 • 6 citations