Bcl-xL Expression Correlates with Primary Macrophage Differentiation, Activation of Functional Competence, and Survival and Results from Synergistic Transcriptional Activation by Ets2 and PU.1

Requirement of Transcription Factor PU.1 in the Development of Multiple Hematopoietic Lineages

1994 • 1,506 citations

Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities.

1996 • 1,115 citations

Molecular cloning and expression of a receptor for human tumor necrosis factor

1990 • 973 citations

The Ets family of transcription factors

1993 • 848 citations

Endotoxin signal transduction in macrophages

1996 • 803 citations

Bcl-XL and Bcl-2 repress a common pathway of cell death.

1995 • 406 citations

Defective trophoblast function in mice with a targeted mutation of Ets2

1998 • 299 citations

Bclx regulates the survival of double-positive thymocytes.

1995 • 249 citations

Down's syndrome-like skeletal abnormalities in Ets2 transgenic mice

1996 • 204 citations

Myc rescue of a mutant CSF-1 receptor impaired in mitogenic signalling

1991 • 175 citations

Regulation of Urokinase-Type Plasminogen Activator Gene Transcription by Macrophage Colony-Stimulating Factor

1995 • 130 citations

Transcriptional regulation of the bcl-x gene encoding the anti-apoptotic Bcl-xL protein by Ets, Rel/NFkappaB, STAT and AP1 transcription factor families.

2001 • 127 citations

Electroporation and DNA‐dependent cell death in murine macrophages

1993 • 122 citations

Identification in chickens of an evolutionarily conserved cellular ets-2 gene (c-ets-2) encoding nuclear proteins related to the products of the c-ets proto-oncogene.

1988 • 122 citations

Colony-stimulating factor 1-induced STAT1 and STAT3 activation is accompanied by phosphorylation of Tyk2 in macrophages and Tyk2 and JAK1 in fibroblasts

1995 • 119 citations

Mitogenic stimulation of thymocytes results in the calcium-dependent phosphorylation of c-ets-1 proteins.

1988 • 118 citations

Selective regulation ofBcl-X_Lby a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies

1998 • 110 citations

The Ets2 Transcription Factor Inhibits Apoptosis Induced by Colony-Stimulating Factor 1 Deprivation of Macrophages through a Bcl-x_L-Dependent Mechanism

1999 • 100 citations

Regulation of bcl-2, bcl-XL and bax in the control of apoptosis by hematopoietic cytokines and dexamethasone.

1995 • 94 citations

A Physiologic Role of Bcl-xL Induced in Activated Macrophages

1998 • 76 citations

The Expression of Bcl-x Is Downregulated During Differentiation of Human Hematopoietic Progenitor Cells Along the Granulocyte But Not the Monocyte/Macrophage Lineage

1997 • 75 citations

ets-2 Is a Target for an Akt (Protein Kinase B)/Jun N-Terminal Kinase Signaling Pathway in Macrophages of motheaten-viable Mutant Mice

2000 • 70 citations

Biochemical events accompanying macrophage activation and the inhibition of colony‐stimulating factor‐1‐induced macrophage proliferation by tumor necrosis factor‐α, interferon‐γ, and lipopolysaccharide

1992 • 63 citations

Multiple motifs regulate the B-cell-specific promoter of the B29 gene.

1993 • 61 citations

Mouse NIH 3T3 cells expressing human colony-stimulating factor 1 (CSF-1) receptors overgrow in serum-free medium containing human CSF-1 as their only growth factor.

1989 • 55 citations

Rapid and transient expression of Ets2 in mature macrophages following stimulation with cMGF, LPS, and PKC activators.

1990 • 53 citations

Cross-family interaction between the bHLHZip USF and bZip Fra1 proteins results in down-regulation of AP1 activity

1997 • 52 citations

Alterations in Differentiation and Behavior of Monocytic Phagocytes in Transgenic Mice that Express Dominant Suppressors of ras Signaling

1995 • 50 citations

The ETS Family of Transcriptional Regulators

1997 • 50 citations

IFN-gamma/lipopolysaccharide activation of macrophages is associated with protein kinase C-dependent down-modulation of the colony-stimulating factor-1 receptor.

1992 • 48 citations

The BH3 Domain of Bcl-x_S Is Required for Inhibition of the Antiapoptotic Function of Bcl-x_L

1999 • 46 citations

Constitutive c-ets2 Expression in M1D+ Myeloblast Leukemic Cells Induces Their Differentiation to Macrophages

1996 • 38 citations

Monocytic differentiation of HL-60 promyelocytic leukemia cells correlates with the induction of Bcl-xL.

1997 • 37 citations

IFN-gamma and lipopolysaccharide induce DNA binding of transcription factor PU.1 in murine tissue macrophages.

1995 • 32 citations

Identification in chicken macrophages of a set of proteins related to, but distinct from, the chicken cellular c-ets-encoded protein p54c-ets.

1986 • 27 citations

Direct synergistic effects of leukemia inhibitory factor on hematopoietic progenitor cell growth: comparison with other hematopoietins that use the gp130 receptor subunit

1996 • 21 citations

Complete Sequencing of the Murine USF Gene and Comparison of Its Genomic Organization to That of mFIP/USF2

1996 • 17 citations

Synergistic effects of colony-stimulating factor 1 and leukemia inhibitory factor in inducing early myeloid cell differentiation.

1998 • 7 citations