Mouse NIH 3T3 cells expressing human colony-stimulating factor 1 (CSF-1) receptors overgrow in serum-free medium containing human CSF-1 as their only growth factor.

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.

1980 • 1,184 citations

Dual control of cell growth by somatomedins and platelet-derived growth factor.

1979 • 926 citations

Induction of DNA synthesis in BALB/c 3T3 cells by serum components: Reevaluation of the commitment process

1977 • 695 citations

Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system

1982 • 680 citations

Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor

1982 • 675 citations

Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroy

1982 • 671 citations

Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells

1987 • 657 citations

Epidermal-Growth-Factor-Dependent Transformation by a Human EGF Receptor Proto-Oncogene

1987 • 448 citations

Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor.

1983 • 395 citations

Platelet-derived growth factor. II. Specific binding to cultured cells.

1982 • 366 citations

Transforming potential of the c-fms proto-oncogene (CSF-1 receptor)

1987 • 357 citations

Platelet-derived growth factor stimulates tyrosine-specific protein kinase activity in Swiss mouse 3T3 cell membranes.

1982 • 293 citations

A point mutation in the extracellular domain of the human CSF-1 receptor (c-fms proto-oncogene product) activates its transforming potential

1988 • 242 citations

Involvement of common and cell type-specific pathways in c-fos gene control: Stable induction by cAMP in macrophages

1987 • 223 citations

The regulation of mononuclear phagocyte entry into S phase by the colony stimulating factor CSF‐1

1985 • 178 citations

Structure-function studies of a colony stimulating factor (CSF-1).

1982 • 175 citations

Tandem linkage of human CSF-1 receptor (c-fms) and PDGF receptor genes

1988 • 172 citations

Activation of the feline c-fms proto-oncogene: Multiple alterations are required to generate a fully transformed phenotype

1988 • 164 citations

The Product of the c- fms Proto-Oncogene: a Glycoprotein with Associated Tyrosine Kinase Activity

1985 • 162 citations

Cell Surface Expression of v-fms-Coded Glycoproteins Is Required for Transformation

1984 • 131 citations

Monoclonal antibodies to the human CSF-1 receptor (c-fms proto-oncogene product) detect epitopes on normal mononuclear phagocytes and on human myeloid leukemic blast cells

1989 • 94 citations

CSF-1-induced gene expression in macrophages: dissociation from the mitogenic response.

1987 • 78 citations

Growth factor requirements of oncogene-transformed NIH 3T3 and BALB/c 3T3 cells cultured in defined media.

1986 • 62 citations

Inhibition of colony-stimulating factor-1 activity by monoclonal antibodies to the human CSF-1 receptor

1989 • 50 citations

Colony-stimulating factor 1-mediated regulation of a chimeric c-fms/v-fms receptor containing the v-fms-encoded tyrosine kinase domain.

1988 • 26 citations

Growth Factor Requirements of Oncogene-Transformed NIH 3T3 and BALB/c 3T3 Cells Cultured in Defined Media

1986 • 19 citations

Colony stimulating factor-1 induced growth stimulation of v-fms transformed fibroblasts.

1988 • 12 citations