Cyclin K Functions as a CDK9 Regulatory Subunit and Participates in RNA Polymerase II Transcription

A Novel CDK9-Associated C-Type Cyclin Interacts Directly with HIV-1 Tat and Mediates Its High-Affinity, Loop-Specific Binding to TAR RNA

1998 • 1,213 citations

NELF, a Multisubunit Complex Containing RD, Cooperates with DSIF to Repress RNA Polymerase II Elongation

1999 • 797 citations

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

1998 • 718 citations

Transcription elongation factor P-TEFb is required for HIV-1 Tat transactivation in vitro

1997 • 692 citations

Control of RNA Polymerase II Elongation Potential by a Novel Carboxyl-terminal Domain Kinase

1996 • 645 citations

Purification of P-TEFb, a Transcription Factor Required for the Transition into Productive Elongation

1995 • 544 citations

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

1997 • 539 citations

Identification of multiple cyclin subunits of human P-TEFb

1998 • 512 citations

The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein

1998 • 428 citations

Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription invitro

1998 • 343 citations

Recruitment of a protein complex containing Tat and cyclin T1 to TAR governs the species specificity of HIV-1 Tat

1998 • 263 citations

RNA Polymerase II Elongation Control

1998 • 238 citations

Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages

1998 • 200 citations

Tat-Associated Kinase, TAK, Activity Is Regulated by Distinct Mechanisms in Peripheral Blood Lymphocytes and Promonocytic Cell Lines

1998 • 145 citations

Upregulation of cyclin T1/CDK9 complexes during T cell activation

1998 • 130 citations

The Transcriptional Inhibitors, Actinomycin D and α-Amanitin, Activate the HIV-1 Promoter and Favor Phosphorylation of the RNA Polymerase II C-terminal Domain

1999 • 100 citations

Human Cyclin K, a Novel RNA Polymerase II-Associated Cyclin Possessing Both Carboxy-Terminal Domain Kinase and Cdk-Activating Kinase Activity

1998 • 94 citations

Host-cell positive transcription elongation factor b kinase activity is essential and limiting for HIV type 1 replication

1999 • 71 citations

Unusual Nucleic Acid Binding Properties of Factor 2, an RNA Polymerase II Transcript Release Factor

1998 • 23 citations