Regulatory T cells inhibit acute IFN-γ synthesis without blocking T-helper cell type 1 (Th1) differentiation via a compartmentalized requirement for IL-10

Differentiation of Effector CD4 T Cell Populations

2010 • 3,135 citations

CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production

1998 • 2,658 citations

The inhibitory cytokine IL-35 contributes to regulatory T-cell function

2007 • 1,886 citations

Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression

2009 • 1,688 citations

An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation

1999 • 1,607 citations

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state.

1998 • 1,579 citations

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

2008 • 1,438 citations

Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major

2007 • 1,346 citations

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

2009 • 1,171 citations

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

2009 • 1,079 citations

The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

2008 • 999 citations

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

2002 • 985 citations

CD4 ⁺ Regulatory T Cells Control T _H 17 Responses in a Stat3-Dependent Manner

2009 • 934 citations

Regulation of Lymphokine Messenger RNA Stability by a Surface-Mediated T Cell Activation Pathway

1989 • 910 citations

Regulatory T cells in tumor immunity

2010 • 902 citations

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

2009 • 898 citations

IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression.

1993 • 862 citations

Interleukin-10 Signaling in Regulatory T Cells Is Required for Suppression of Th17 Cell-Mediated Inflammation

2011 • 834 citations

Cyclic adenosine monophosphate is a key component of regulatory T cell–mediated suppression

2007 • 618 citations

Th17 Cells Express Interleukin-10 Receptor and Are Controlled by Foxp3− and Foxp3+ Regulatory CD4+ T Cells in an Interleukin-10-Dependent Manner

2011 • 568 citations

Regulatory T Cells Reversibly Suppress Cytotoxic T Cell Function Independent of Effector Differentiation

2006 • 475 citations

Regulatory T Cells in the Control of Host-Microorganism Interactions

2009 • 469 citations

Contextual Regulation of Inflammation: A Duet by Transforming Growth Factor-β and Interleukin-10

2008 • 454 citations

Characterization of Foxp3+CD4+CD25+ and IL-10-Secreting CD4+CD25+ T Cells during Cure of Colitis

2006 • 448 citations

T Regulatory and Primed Uncommitted CD4 T Cells Express CD73, Which Suppresses Effector CD4 T Cells by Converting 5′-Adenosine Monophosphate to Adenosine

2006 • 440 citations

Altering the distribution of Foxp3+ regulatory T cells results in tissue-specific inflammatory disease

2007 • 388 citations

Regulatory T Cells Sequentially Migrate from Inflamed Tissues to Draining Lymph Nodes to Suppress the Alloimmune Response

2009 • 382 citations

Mechanisms of regulatory T‐cell suppression – a diverse arsenal for a moving target

2008 • 357 citations

A Role for CD103 in the Retention of CD4+CD25+ Treg and Control of Leishmania major Infection

2005 • 313 citations

Sequential Polarization and Imprinting of Type 1 T Helper Lymphocytes by Interferon-γ and Interleukin-12

2009 • 254 citations

Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo

2005 • 250 citations

How Punctual Ablation of Regulatory T Cells Unleashes an Autoimmune Lesion within the Pancreatic Islets

2009 • 237 citations

Colitogenic Th1 Cells Are Present in the Antigen-Experienced T Cell Pool in Normal Mice: Control by CD4+ Regulatory T Cells and IL-10

2003 • 176 citations

Dendritic Cell Antigen Presentation Drives Simultaneous Cytokine Production by Effector and Regulatory T Cells in Inflamed Skin

2009 • 155 citations

Janus-Kinase-3-Dependent Signals Induce Chromatin Remodeling at the Ifng Locus during T Helper 1 Cell Differentiation

2008 • 127 citations

CD4+CD25+ T Cells Prevent the Development of Organ-Specific Autoimmune Disease by Inhibiting the Differentiation of Autoreactive Effector T Cells

2005 • 125 citations

CD4+CD25+ Cells Controlling a Pathogenic CD4 Response Inhibit Cytokine Differentiation, CXCR-3 Expression, and Tissue Invasion

2004 • 122 citations

CTLA‐4 is required by CD4⁺CD25⁺ Treg to control CD4⁺ T‐cell lymphopenia‐induced proliferation

2009 • 99 citations

Secretion of IL-2 and IFN-γ, But Not IL-4, by Antigen-Specific T Cells Requires Extracellular ATP

2003 • 79 citations

Cutting Edge: CD28-Mediated Transcriptional and Posttranscriptional Regulation of IL-2 Expression Are Controlled through Different Signaling Pathways

2004 • 79 citations

Early Kinetic Window of Target T Cell Susceptibility to CD25+ Regulatory T Cell Activity

2005 • 68 citations