Secretion of IL-2 and IFN-γ, But Not IL-4, by Antigen-Specific T Cells Requires Extracellular ATP

T cell receptor antagonist peptides induce positive selection

1994 • 2,818 citations

Induction by Antigen of Intrathymic Apoptosis of CD4 ⁺ CD8 ⁺ TCR ^lo Thymocytes in Vivo

1990 • 1,781 citations

Nomenclature and classification of purinoceptors.

1994 • 1,569 citations

Introduction of soluble protein into the class I pathway of antigen processing and presentation

1988 • 1,105 citations

Extracellular metabolism of ATP and other nucleotides

2000 • 973 citations

Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines.

1991 • 835 citations

T CELL ANTIGEN RECEPTOR SIGNAL TRANSDUCTION PATHWAYS

1996 • 692 citations

Expression cloning of an ATP receptor from mouse neuroblastoma cells.

1993 • 587 citations

Identification and Characterization of CD39/Vascular ATP Diphosphohydrolase

1996 • 566 citations

Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation

1999 • 554 citations

Ecto-ATPases: Identities and Functions

1995 • 503 citations

Different Nuclear Signals Are Activated by the B Cell Receptor during Positive Versus Negative Signaling

1997 • 383 citations

The multidrug resistance (mdr1) gene product functions as an ATP channel.

1993 • 372 citations

Differential Regulation of Murine T Lymphocyte Subsets

1993 • 343 citations

Ionomycin enhances Ca2+ influx by stimulating store-regulated cation entry and not by a direct action at the plasma membrane

1994 • 305 citations

Two better cell lines for making hybridomas expressing specific T cell receptors.

1989 • 300 citations

CD39 Is an Ecto-(Ca2+,Mg2+)-apyrase

1996 • 290 citations

The CD39 lymphoid cell activation antigen. Molecular cloning and structural characterization.

1994 • 256 citations

Specific assays for cytokine production by T cells

1989 • 228 citations

Evidence implicating utilization of different T cell receptor-associated signaling pathways by TH1 and TH2 clones.

1990 • 218 citations

Salmonella typhimurium induces epithelial IL-8 expression via Ca2+-mediated activation of the NF-κB pathway

2000 • 214 citations

Capacitative Ca2+ Entry Is Closely Linked to the Filling State of Internal Ca2+ Stores: A Study Using Simultaneous Measurements of ICRAC and Intraluminal [Ca2+]

1998 • 213 citations

Expression, distribution, and biochemistry of human CD39. Role in activation-associated homotypic adhesion of lymphocytes.

1991 • 208 citations

Extracellular ATP in T-lymphocyte activation: possible role in effector functions.

1990 • 196 citations

Characterization of T cell mutants with defects in capacitative calcium entry: genetic evidence for the physiological roles of CRAC channels.

1995 • 179 citations

Heterogeneity of single cell cytokine gene expression in clonal T cell populations.

1994 • 173 citations

Single cell analysis of cytokine gene coexpression during CD4+ T-cell phenotype development.

1995 • 146 citations

Calcium-dependent potentiation of store-operated calcium channels in T lymphocytes.

1996 • 137 citations

Affinity labeling of the inhibitory DPNH site of bovine liver glutamate dehydrogenase by 5'-fluorosulfonylbenzoyl adenosine.

1975 • 135 citations

Exogenous antigens gain access to the major histocompatibility complex class I processing pathway in B cells by receptor-mediated uptake.

1996 • 111 citations

Origin, metabolism and function of extracellular adenine nucleotides in the blood

1989 • 102 citations

IL-1 activates two separate signal transduction pathways in T helper type II cells.

1990 • 101 citations

Purification of the blood vessel ATP diphosphohydrolase, identification and localisation by immunological techniques

1997 • 98 citations

The biological actions of extracellular ATP

1989 • 96 citations

Selective loss of the calcium ion signaling pathway in T cells maturing toward a T helper 2 phenotype.

1997 • 87 citations

Ovalbumin injected with complete Freund's adjuvant stimulates cytolytic responses

1995 • 82 citations

Establishment of B cell hybridomas with B cell surface antigens.

1982 • 80 citations

Purification of pancreas type-I ATP diphosphohydrolase and identification by affinity labelling with the 5′-p-fluorosulphonylbenzoyladenosine ATP analogue

1995 • 72 citations

P2Y11 Receptors Activate Adenylyl Cyclase and Contribute to Nucleotide-promoted cAMP Formation in MDCK-D1Cells

2002 • 55 citations

Extracellular Adenine Nucleotides Inhibit the Activation of Human CD4+ T Lymphocytes

2002 • 52 citations

Antigen Is Required for the Activation of Effector Activities, whereas Interleukin 2 Is Required for the Maintenance of Memory in Ovalbumin-specific, CD8+ Cytotoxic T Lymphocytes

1998 • 48 citations

Purinoceptor function in the immune system

1996 • 46 citations

P₂‐Purinoceptor Antagonists^a

1990 • 44 citations

Antigen recognition by CTL is dependent upon ectoATPase activity.

1995 • 36 citations

The pharmacology and kinetics of ecto-nucleotidases in the perilymphatic compartment of the guinea-pig cochlea

1998 • 36 citations

Identification and partial characterization of an ectoATPase expressed by human natural killer cells

1993 • 36 citations

ATP transport and ABC proteins

1996 • 34 citations

Inhibition of Ecto-ATPase by the P2Purinoceptor Agonists, ATPγS, α,β-Methylene-ATP, and AMP-PNP, in Endothelial Cells

1997 • 32 citations

Delivery of exogenous antigen into the major histocompatibility complex class I and class II pathways by electroporation

1994 • 29 citations

Irreversible inhibition of human natural killer cell natural cytotoxicity by modification of the extracellular membrane by the adenine nucleotide analog 5′-p-(fluorosulfonyl)benzoyl adenosine

1995 • 17 citations

Inversions in the factor VIII gene in Spanish hemophilia A patients [letter]

1994 • 15 citations

Identification and Partial Characterization of EctoATPase Expressed by Immortalized B Lymphocytes

1997 • 12 citations

Extracellular ATP Metabolism in B and T Lymphocytes

1990 • 11 citations

CD39 as a novel marker of in vivo immune activation [letter; comment]

1994 • 8 citations

Bovine Insulin and Porcine or Human Insulin Prime Distinct CD4+ T Cell Subsets in C57BL/6 Mice

1999 • 5 citations

Role of Ecto-ATPase in Lymphocyte Function

1997 • 5 citations

Affinity Labeling of Nucleotide Binding Sites of Enzymes and Platelets

1990 • 3 citations