A Subset of Fibroblast Growth Factors (Fgfs) Promote Survival, but Fgf-8b Specifically Promotes Astroglial Differentiation of Rat Cortical Precursor Cells

Growth of a rat neuroblastoma cell line in serum-free supplemented medium.

1979 • 2,285 citations

Mode of cell migration to the superficial layers of fetal monkey neocortex

1972 • 2,145 citations

Receptor Specificity of the Fibroblast Growth Factor Family

1996 • 1,871 citations

The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo

1995 • 1,175 citations

Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.

1996 • 1,164 citations

Fibroblast Growth Factor Receptor 3 Is a Negative Regulator of Bone Growth

1996 • 1,062 citations

Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor

1996 • 1,027 citations

Regulation of Gliogenesis in the Central Nervous System by the JAK-STAT Signaling Pathway

1997 • 993 citations

Progress in Nucleic Acid Research and Molecular Biology

2001 • 936 citations

Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer.

1987 • 881 citations

FGF and Shh Signals Control Dopaminergic and Serotonergic Cell Fate in the Anterior Neural Plate

1998 • 868 citations

Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3

1996 • 867 citations

An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis

2000 • 847 citations

Distinct Neural Stem Cells Proliferate in Response to EGF and FGF in the Developing Mouse Telencephalon

1999 • 807 citations

Cleavage orientation and the asymmetric inheritance of notchl immunoreactivity in mammalian neurogenesis

1995 • 764 citations

Bone Morphogenetic Proteins Promote Astroglial Lineage Commitment by Mammalian Subventricular Zone Progenitor Cells

1996 • 681 citations

Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse

1992 • 676 citations

Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation

1994 • 665 citations

bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells

1993 • 651 citations

Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development

1998 • 618 citations

Widespread Dispersion of Neuronal Clones Across Functional Regions of the Cerebral Cortex

1992 • 610 citations

A self-renewing multipotential stem cell in embryonic rat cerebral cortex

1994 • 578 citations

Numbers, time and neocortical neuronogenesis: a general developmental and evolutionary model

1995 • 572 citations

Cell lineage in the cerebral cortex of the mouse studied in vivo and in vitro with a Recombinant Retrovirus

1988 • 569 citations

Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia

1996 • 500 citations

Astroglial and fibroblast growth factors have neurotrophic functions for cultured peripheral and central nervous system neurons.

1987 • 495 citations

Distinct roles for bFGF and NT-3 in the regulation of cortical neurogenesis

1995 • 476 citations

Unique Expression Pattern of the FGF Receptor 3 Gene during Mouse Organogenesis

1993 • 456 citations

FGF2 Concentration Regulates the Generation of Neurons and Glia from Multipotent Cortical Stem Cells

1997 • 455 citations

Impaired cerebral cortex development and blood pressure regulation in FGF-2-deficient mice

1998 • 437 citations

Cell lineage in the rat cerebral cortex: a study using retroviral-mediated gene transfer

1988 • 421 citations

Developmental Regulation of Neural Response to FGF-1 and FGF-2 by Heparan Sulfate Proteoglycan

1993 • 420 citations

Constructing the cerebral cortex: Neurogenesis and fate determination

1995 • 415 citations

The Heparan Sulfate–Fibroblast Growth Factor Family: Diversity of Structure and Function

1997 • 400 citations

Changes in cerebral cortex size are governed by fibroblast growth factor during embryogenesis

1999 • 397 citations

Multiple Routes to Astrocytic Differentiation in the CNS

1998 • 389 citations

Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development.

1996 • 385 citations

Proliferating bipotential glial progenitor cells in adult rat optic nerve

1986 • 378 citations

Brain basic fibroblast growth factor stimulates the proliferation of rat neuronal precursor cells in vitro

1987 • 336 citations

Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain

1997 • 326 citations

Characterization of Recombinant Human Fibroblast Growth Factor (FGF)-10 Reveals Functional Similarities with Keratinocyte Growth Factor (FGF-7)

1998 • 307 citations

A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth

1995 • 303 citations

Fibroblast growth factor receptor (FGFR) 3. Alternative splicing in immunoglobulin-like domain III creates a receptor highly specific for acidic FGF/FGF-1

1994 • 301 citations

Multiple Roles of Bone Morphogenetic Protein Signaling in the Regulation of Cortical Cell Number and Phenotype

1999 • 279 citations

FGF-7 (keratinocyte growth factor) expression during mouse development suggests roles in myogenesis, forebrain regionalisation and epithelial-mesenchymal interactions

1994 • 275 citations

The generation of neurons and oligodendrocytes from a common precursor cell

1991 • 274 citations

Fgf-8 expression in the post-gastrulation mouse suggests roles in the development of the face, limbs and central nervous system

1994 • 272 citations

Evidence for the ventral origin of oligodendrocyte precursors in the rat spinal cord

1991 • 268 citations

Expression of FGF receptor gene in rat development

1991 • 264 citations

Fibroblast growth factor stimulates the proliferation and differentiation of neural precursor cells in vitro

1990 • 257 citations

NUMB Localizes in the Basal Cortex of Mitotic Avian Neuroepithelial Cells and Modulates Neuronal Differentiation by Binding to NOTCH-1

1999 • 256 citations

Intrinsic programs of patterned cell lineages in isolated vertebrate CNS ventricular zone cells

1998 • 243 citations

Embryonic expression of myelin genes: Evidence for a focal source of oligodendrocyte precursors in the ventricular zone of the neural tube

1994 • 241 citations

Cloned multipotential precursors from the mouse cerebrum require FGF-2, whereas glial restricted precursors are stimulated with either FGF-2 or EGF

1995 • 238 citations

A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1

1997 • 228 citations

Structure and expression of a novel human FGF, FGF-19, expressed in the fetal brain

1999 • 226 citations

FGF-8 isoforms activate receptor splice forms that are expressed in mesenchymal regions of mouse development

1995 • 223 citations

Radial and horizontal deployment of clonally related cells in the primate neocortex: Relationship to distinct mitotic lineages

1995 • 212 citations

Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain

1999 • 207 citations

Evidence for multiple precursor cell types in the embryonic rat cerebral cortex

1995 • 182 citations

Multiple restricted lineages in the embryonic rat cerebral cortex

1993 • 166 citations

bFGF, neurotrophins, and the control of cortical neurogenesis

1995 • 161 citations

Regulation of FGF Receptors in the Oligodendrocyte Lineage

1996 • 160 citations

Structure and Expression of a Novel Member, FGF-16, of the Fibroblast Growth Factor Family

1998 • 152 citations

Structure and Expression of the mRNA Encoding a Novel Fibroblast Growth Factor, FGF-18

1998 • 150 citations

Lineage analysis reveals neurotransmitter (GABA or glutamate) but not calcium-binding protein homogeneity in clonally related cortical neurons

1994 • 142 citations

Differential expression patterns of mRNAs for members of the fibroblast growth factor receptor family, FGFR‐1–FGFR‐4, in rat brain

1994 • 141 citations

Promiscuity of fibroblast growth factor receptors

1996 • 140 citations

Murine FGF-12 and FGF-13: expression in embryonic nervous system, connective tissue and heart

1997 • 139 citations

Cell Fate Specification and Symmetrical/Asymmetrical Divisions in the Developing Cerebral Cortex

1997 • 134 citations

Genomic structure, mapping, activity and expression of fibroblast growth factor 17

1999 • 115 citations

Dorsal Spinal Cord Neuroepithelium Generates Astrocytes but Not Oligodendrocytes

1998 • 112 citations

Evidence that retroviruses integrate into post-replication host DNA.

1993 • 110 citations

Structure and Expression of a Novel Fibroblast Growth Factor, FGF-17, Preferentially Expressed in the Embryonic Brain

1998 • 103 citations

FGF-8 isoforms differ in NIH3T3 cell transforming potential.

1995 • 94 citations

Expression of EGF receptor and FGF receptor isoforms during neuroepithelial stem cell differentiation

1999 • 91 citations

Temporal, differential and regional expression of mRNA for basic fibroblast growth factor in the developing and adult rat brain

1991 • 90 citations

Heparan Sulfates Mediate the Binding of Basic Fibroblast Growth Factor to a Specific Receptor on Neural Precursor Cells

1995 • 89 citations

Origin of Oligodendrocytes within the Human Spinal Cord

1996 • 88 citations

Expression of Fgf4 during early development of the chick embryo

1999 • 85 citations

Basic fibroblast growth factor prolongs the proliferation of rat cortical progenitor cells in vitro without altering their cell cycle parameters

1997 • 80 citations

Neocortical Development

1992 • 76 citations

Rat oligodendrocytes and astrocytes preferentially express fibroblast growth factor receptor-2 and -3 mRNAs

1996 • 71 citations

Glial Cell Developmentbasic principles and clinical relevance

1997 • 64 citations

Glial cell development. Basic principles and clinical relevance

1996 • 52 citations

The Fibroblast Growth Factor Receptor-1 Is Necessary for the Induction of Neurite Outgrowth in PC12 Cells by aFGF

1996 • 35 citations

Fibroblast growth factor 2 increases Otx2 expression in precursor cells from mammalian telencephalon

1995 • 22 citations

Origins and early development of oligodendrocytes

1997 • 9 citations

Glial cell lineages in the developing central nervous system

1995 • 2 citations