Stimulation of lymphocyte responses by angiotensin II promotes kidney injury in hypertension

Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Nephropathy

2001 • 7,165 citations

Renoprotective Effect of the Angiotensin-Receptor Antagonist Irbesartan in Patients with Nephropathy Due to Type 2 Diabetes

2001 • 5,812 citations

Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol

2002 • 5,471 citations

Role of the T cell in the genesis of angiotensin II–induced hypertension and vascular dysfunction

2007 • 1,612 citations

Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms

2005 • 1,161 citations

Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells.

1994 • 1,063 citations

Microalbuminuria Reduction With Valsartan in Patients With Type 2 Diabetes Mellitus

2002 • 794 citations

Inflammation and angiotensin II

2003 • 676 citations

Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney

2006 • 663 citations

Regulation of blood pressure by the type 1A angiotensin II receptor gene.

1995 • 599 citations

Angiotensin-Converting Enzyme Inhibition Prevents Arterial Nuclear Factor-κB Activation, Monocyte Chemoattractant Protein-1 Expression, and Macrophage Infiltration in a Rabbit Model of Early Accelerated Atherosclerosis

1997 • 502 citations

Regression of Hypertensive Left Ventricular Hypertrophy by Losartan Compared With Atenolol

2004 • 458 citations

Interactions of Transforming Growth Factor-β and Angiotensin II in Renal Fibrosis

1998 • 441 citations

NF-κB Inhibition Ameliorates Angiotensin II–Induced Inflammatory Damage in Rats

2000 • 404 citations

Isolation and characterization of the human pulmonary surfactant apoprotein gene

1985 • 397 citations

Granzyme A Induces Caspase-Independent Mitochondrial Damage, a Required First Step for Apoptosis

2005 • 371 citations

Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice.

1998 • 354 citations

Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach

2005 • 333 citations

Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway

1999 • 305 citations

Immunosuppressive Treatment Protects Against Angiotensin II-Induced Renal Damage

2002 • 273 citations

T Cell Activation and the Cytoskeleton

2000 • 264 citations

Angiotensin II stimulates expression of the chemokine RANTES in rat glomerular endothelial cells. Role of the angiotensin type 2 receptor.

1997 • 255 citations

Tumor necrosis factor induces glomerular damage in the rabbit.

1989 • 244 citations

Mycophenolate mofetil prevents salt-sensitive hypertension resulting from angiotensin II exposure

2001 • 232 citations

Model of robust induction of glomerulosclerosis in mice: Importance of genetic background

2003 • 230 citations

Monocyte Infiltration and Adhesion Molecules in a Rat Model of High Human Renin Hypertension

1999 • 220 citations

Mycophenolate mofetil prevents the progressive renal failure induced by 5/6 renal ablation in rats

1999 • 203 citations

Imbalance of T-Cell Subsets in Angiotensin II–Infused Hypertensive Rats With Kidney Injury

2003 • 203 citations

Getting Membrane Flow and the Cytoskeleton to Cooperate in Moving Cells

1996 • 192 citations

Immune Suppression Attenuates Hypertension and Renal Disease in the Dahl Salt-Sensitive Rat

2006 • 165 citations

Agonist-stimulated cytoskeletal reorganization and signal transduction at focal adhesions in vascular smooth muscle cells require c-Src

1999 • 161 citations

Cloning and Characterization of Two New Isoforms of the Rat Kidney Urea Transporter

1999 • 158 citations

Cytoskeletal rearrangement during migration and activation of T lymphocytes

1999 • 152 citations

IL-10 Suppresses Chemokines, Inflammation, and Fibrosis in a Model of Chronic Renal Disease

2005 • 145 citations

Role for Thromboxane Receptors in Angiotensin-II–Induced Hypertension

2004 • 144 citations

Strain differences in the development of hypertension and glomerular lesions induced by deoxycorticosterone acetate salt in mice

2003 • 132 citations

Attenuation of murine lupus nephritis by mycophenolate mofetil.

1998 • 128 citations

Molecular phenotyping for analyzing subtle genetic effects in mice: Application to an angiotensinogen gene titration

2002 • 124 citations

Chronic allograft nephropathy in the rat is improved by angiotensin II receptor blockade but not by calcium channel antagonism.

1998 • 120 citations

Renoprotection by ACE Inhibition or Aldosterone Blockade Is Blood Pressure–Dependent

2003 • 116 citations

Chronic Blockade of NO Synthase Activity Induces a Proinflammatory Phenotype in the Arterial Wall

1998 • 115 citations

Angiotensin III increases MCP-1 and activates NF-кB and AP-1 in cultured mesangial and mononuclear cells

2000 • 114 citations

Lymphokine dependence of in vivo expression of MHC class II antigens by endothelium

1985 • 106 citations

Involvement of tumor necrosis factor and platelet-activating factor in the pathogenesis of experimental nephrosis in rats.

1994 • 105 citations

Immunohistochemical detection of T-cell subsets and other leukocytes in paraffin-embedded rat and mouse tissues with monoclonal antibodies.

1995 • 103 citations

Progression of Renal Disease

2006 • 97 citations

ICAM-1 antisense oligodesoxynucleotides prevent reperfusion injury and enhance immediate graft function in renal transplantation

1998 • 97 citations

Vasoactive substances induce cytoskeletal changes in cultured rat glomerular epithelial cells.

1992 • 94 citations

Rho Kinase Promotes Alloimmune Responses by Regulating the Proliferation and Structure of T Cells

2003 • 72 citations

Involvement of Rho-Kinase Pathway for Angiotensin II-Induced Plasminogen Activator Inhibitor-1 Gene Expression and Cardiovascular Remodeling in Hypertensive Rats

2002 • 71 citations

Experimental and clinical evidence that angiotensin II is an independent risk factor for cardiovascular disease

2001 • 69 citations

Beneficial effect of the inosine monophosphate dehydrogenase inhibitor mycophenolate mofetil on survival and severity of glomerulonephritis in systemic lupus erythematosus (SLE)-prone MRLlpr/lprmice

1999 • 69 citations

Enhanced renal leukotriene production in murine lupus: Role of lipoxygenase metabolites

1991 • 67 citations

Screening and identification of substances that regulate nephrin gene expression using engineered reporter podocytes

2006 • 67 citations

In mice, proteinuria and renal inflammatory responses to albumin overload are strain-dependent

2005 • 67 citations

TP receptors regulate renal hemodynamics during angiotensin II slow pressor response

2004 • 63 citations

Mycophenolate Mofetil Reduces Renal Injury in the Chronic Nitric Oxide Synthase Inhibition Model

2001 • 54 citations

Leukotrienes in renal transplant rejection in rats. Distinct roles for leukotriene B4 and peptidoleukotrienes in the pathogenesis of allograft injury.

1994 • 49 citations

Exploring type I angiotensin (AT₁) receptor functions through gene targeting

2004 • 47 citations

Low Levels of IFN-γ Down-regulate the Integrin-dependent Adhesion of B Cells by Activating a Pathway That Interferes with Cytoskeleton Rearrangement

2001 • 32 citations

Modulation of autoantibody production by mycophenolate mofetil: effects on the development of SLE in (NZBxNZW)F1 mice

2003 • 32 citations

Induction of MHC class II molecules HLA-DR, -DP and -DQ and ICAM 1 in human podocytes by gamma-interferon.

1994 • 24 citations

Biological Alterations of Rat Podocytes Cultured under Basolateral Hydrostatic Pressure

1996 • 9 citations