Cloning and characterization of human karyopherin β3

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex.

1996 • 1,161 citations

Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins

1995 • 767 citations

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

1993 • 760 citations

Isolation of a protein that is essential for the first step of nuclear protein import

1994 • 710 citations

A Novel Receptor-Mediated Nuclear Protein Import Pathway

1996 • 669 citations

Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor [published erratum appears in J Cell Biol 1994 Jan;124(1-2):217]

1993 • 544 citations

Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope

1995 • 511 citations

Distinct functions for the two importin subunits in nuclear protein import

1995 • 479 citations

The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex

1995 • 460 citations

Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins.

1995 • 430 citations

Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62.

1995 • 385 citations

Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences

1995 • 337 citations

Purification of a Ran-interacting protein that is required for protein import into the nucleus.

1994 • 318 citations

Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope.

1994 • 306 citations

Kap104p: A Karyopherin Involved in the Nuclear Transport of Messenger RNA Binding Proteins

1996 • 306 citations

In vivo evidence for involvement of a 58 kDa component of nuclear pore-targeting complex in nuclear protein import.

1995 • 288 citations

Pores for thought: nuclear pore complex proteins

1994 • 286 citations

Sequence and characterization of cytoplasmic nuclear protein import factor p97.

1995 • 274 citations

Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporins.

1995 • 264 citations

Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4

1993 • 261 citations

Previously identified protein of uncertain function is karyopherin alpha and together with karyopherin beta docks import substrate at nuclear pore complexes.

1995 • 254 citations

Identification of a Yeast Karyopherin Heterodimer That Targets Import Substrate to Mammalian Nuclear Pore Complexes

1995 • 210 citations

The GLFG repetitive region of the nucleoporin Nup116p interacts with Kap95p, an essential yeast nuclear import factor.

1995 • 206 citations

Role of the Nuclear Transport Factor p10 in Nuclear Import

1996 • 166 citations

Karyopherin β2 mediates nuclear import of a mRNA binding protein

1997 • 160 citations

POM152 is an integral protein of the pore membrane domain of the yeast nuclear envelope.

1994 • 145 citations

A Karyophilic Protein Forms a Stable Complex with Cytoplasmic Components Prior to Nuclear Pore Binding

1995 • 144 citations

The Nuclear Transport Factor Karyopherin β Binds Stoichiometrically to Ran-GTP and Inhibits the Ran GTPase Activating Protein

1996 • 123 citations

Nuclear protein import: Ran-GTP dissociates the karyopherin alphabeta heterodimer by displacing alpha from an overlapping binding site on beta.

1996 • 105 citations

Isolation and characterization of a novel gene with differential expression in benign and malignant human breast tumours

1992 • 48 citations

Screening and identification of a gene, PSE-1, that affects protein secretion in Saccharomyces cerevisiae

1992 • 40 citations

A human gene related to the ribosomal protein L23 gene ofHalobacterium marismortui

1990 • 5 citations

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