cDNA cloning and expression of stress‐inducible rat hsp70 normal and injured rat brain

THE HEAT-SHOCK PROTEINS

1988 • 5,214 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

Protein folding in the cell

1992 • 4,138 citations

Speculations on the functions of the major heat shock and glucose-regulated proteins

1986 • 1,574 citations

An hsp70-like protein in the ER: Identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein

1986 • 1,457 citations

Heat shock proteins.

1990 • 1,365 citations

Interaction of Hsp 70 with Newly Synthesized Proteins: Implications for Protein Folding and Assembly

1990 • 1,293 citations

TECHNOLOGICAL EXAMINATION OF LOW‐FIRED TERRACOTTA STATUES FROM AYIA IRINI, KEA

1982 • 1,253 citations

Abnormal Proteins Serve as Eukaryotic Stress Signals and Trigger the Activation of Heat Shock Genes

1986 • 904 citations

Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70.

1985 • 860 citations

Key features of heat shock regulatory elements.

1988 • 566 citations

Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells.

1984 • 522 citations

Cellular and biochemical events in mammalian cells during and after recovery from physiological stress.

1986 • 513 citations

Localization of 70-kDa stress protein induction in gerbil brain after ischemia

1988 • 465 citations

Structure and expression of the human gene encoding major heat shock protein HSP70.

1985 • 461 citations

Coordinated regulation of a set of genes by glucose and calcium ionophores in mammalian cells

1987 • 442 citations

Structure and expression of the three MHC-linked HSP70 genes

1990 • 397 citations

Human major histocompatibility complex contains genes for the major heat shock protein HSP70.

1989 • 336 citations

Human HSP70 promoter contains at least two distinct regulatory domains.

1986 • 326 citations

Heat shock proteins as markers of neural injury

1989 • 304 citations

[7] Random cloning and sequencing by the M13/dideoxynucleotide chain termination method

1987 • 292 citations

Sequence of three copies of the gene for the major Drosophila heat shock induced protein and their flanking regions

1980 • 286 citations

Synthesis of a Stress Protein Following Transient Ischemia in the Gerbil

1985 • 270 citations

Structure and expression of a human gene coding for a 71 kd heat shock ‘cognate’ protein

1987 • 254 citations

Complex regulation of heat shock- and glucose-responsive genes in human cells.

1988 • 242 citations

Human Gene Encoding the 78,000-Dalton Glucose-Regulated Protein and Its Pseudogene: Structure, Conservation, and Regulation

1988 • 236 citations

Trauma-Induced Protein in Rat Tissues: A Physiological Role for a "Heat Shock" Protein?

1981 • 233 citations

MK‐801 and ketamine induce heat shock protein HSP72 in injured neurons in posterior cingulate and retrosplenial cortex

1991 • 233 citations

The temporal profile of 72-kDa heat-shock protein expression following global ischemia

1991 • 206 citations

Heat Shock RNA Levels in Brain and Other Tissues After Hyperthermia and Transient Ischemia

1990 • 199 citations

Cloning and expression of a gene encoding hsc73, the major hsp70-like protein in unstressed rat cells.

1987 • 193 citations

Characterization and sequence of a mouse hsp70 gene and its expression in mouse cell lines

1990 • 187 citations

Induction of 70-kDa Heat Shock Protein and hsp70 mRNA following Transient Focal Cerebral Ischemia in the Rat

1993 • 187 citations

Identification and sequence analysis of a new member of the mouse HSP70 gene family and characterization of its unique cellular and developmental pattern of expression in the male germ line.

1988 • 184 citations

Induction of a heat shock gene at the site of tissue injury in the rat brain

1989 • 183 citations

Induction of stress protein HSP70 in nerve cells after status epilepticus in the rat

1989 • 179 citations

Regional Expression of Heat Shock Protein-70 mRNA and c-Fos mRNA following Focal Ischemia in Rat Brain

1992 • 171 citations

The human heat-shock protein family. Expression of a novel heat-inducible HSP70 (HSP70B′) and isolation of its cDNA and genomic DNA

1990 • 170 citations

Induction of heat shock (stress) genes in the mammalian brain by hyperthermia and other traumatic events: A current perspective

1990 • 170 citations

Constitutively Expressed Rat mRNA Encoding a 70-Kilodalton Heat-Shock-Like Protein

1985 • 164 citations

Isolation and functional analysis of a human 70,000-dalton heat shock protein gene segment.

1985 • 164 citations

Extensive regions of homology in front of the two hsp70 heat shock variant genes in Drosophila melanogaster

1981 • 161 citations

Rat gene encoding the 78-kDa glucose-regulated protein GRP78: its regulatory sequences and the effect of protein glycosylation on its expression.

1987 • 144 citations

Continuous lidocaine infusion and focal feline cerebral ischemia.

1990 • 140 citations

Hypoxia—ischemia induces heat shock protein-like (HSP72) immunoreactivity in neonatal rat brain

1990 • 139 citations

The pattern of 72-kDa heat shock protein-like immunoreactivity in the rat brain following flurothyl-induced status epilepticus

1990 • 139 citations

Heat Shock Protein hsp72 Induction in Cortical and Striatal Astrocytes and Neurons following Infarction

1991 • 135 citations

The role of stress proteins in membrane biogenesis

1988 • 133 citations

Induction of heat shock protein 72-like immunoreactivity in the hippocampal formation following transient global ischemia

1991 • 131 citations

Synthesis of Heat Shock Proteins in Rat Brain Cortex after Transient Ischemia

1986 • 129 citations

Selective Gene Expression in Focal Cerebral Ischemia

1986 • 123 citations

Molecular cloning and analysis of DNA complementary to three mouse Mr = 68,000 heat shock protein mRNAs.

1986 • 116 citations

Expression of Heat Shock Protein 70 and Heat Shock Cognate 70 Messenger RNAs in Rat Cortex and Cerebellum After Heat Shock or Amphetamine Treatment

1991 • 115 citations

Cloning of a hsp70-related gene expressed in mouse spermatids

1990 • 112 citations

Haloperidol prevents induction of the hsp70 heat shock gene in neurons injured by phencyclidine (PCP), MK801, and ketamine

1992 • 106 citations

Constitutively expressed rat mRNA encoding a 70-kilodalton heat-shock-like protein.

1985 • 104 citations

Distribution of the 72-kd heat-shock protein as a function of transient focal cerebral ischemia in rats.

1992 • 100 citations

Heat shock protein in mammalian brain and other organs after a physiologically relevant increase in body temperature induced by D-lysergic acid diethylamide.

1983 • 98 citations

Induction of HSP70 mRNA after transient ischemia in gerbil brain

1991 • 96 citations

Synthesis of the major inducible heat shock protein in rat hippocampus after neonatal hypoxia-ischemia

1989 • 92 citations

Comparison of the heat shock response in cultured cortical neurons and astrocytes

1991 • 90 citations

Expression of heat shock genes (hsp70) in the mammalian brain: Distinguishing constitutively expressed and hyperthermia‐inducible mRNA species

1990 • 81 citations

Distributions of Heat Shock Protein-70 mRNAs and Heat Shock Cognate Protein-70 mRNAs after Transient Global Ischemia in Gerbil Brain

1992 • 76 citations

Neuronal injury and expression of 72-kDa heat-shock protein after forebrain ischemia in the rat

1991 • 73 citations

A human gene family with sequence homology to Drosophila melanogaster Hsp70 heat shock genes.

1986 • 73 citations

β-internexin is a microtubule-associated protein identical to the 70-kDa heat-shock cognate protein and the clathrin uncoating ATPase

1989 • 73 citations

The induction of the major heat‐stress protein in purified rat glial cells

1988 • 58 citations

Hyperthermia Induces the Synthesis of a Heat Shock Protein by Polysomes Isolated from the Fetal and Neonatal Mammalian Brain

1983 • 56 citations

Structure of a gene encoding heat-shock protein HSP70 from the unicellular alga Chlamydomonas reinhardtii

1992 • 54 citations

Axonal Polypeptides Cross‐Reactive with Antibodies to Neurofilament Proteins

1983 • 52 citations

Isolation and nucleotide sequence analysis of the rat testis-specific major heat-shock protein (HSP70)-related gene

1990 • 49 citations

Temporal profile of the induction of heat shock protein 70 and heat shock cognate protein 70 mRNAs after transient ischemia in gerbil brain

1993 • 41 citations

Regulation of heat shock protein synthesis in rat astroeytes

1991 • 36 citations

The Brain 68‐Kilodalton Microtubule‐Associated Protein Is a Cognate Form of the 70‐Kilodalton Mammalian Heat‐Shock Protein and Is Present as a Specific Isoform in Synaptosomal Membranes

1986 • 35 citations

Induction of the major inducible 68-kDa heat-shock protein after rapid changes of extracellular pH in cultured rat astrocytes

1989 • 34 citations

Isolation of a mouse heat-shock gene (hsp68) by recombinational screening

1987 • 33 citations

Expression of heat shock genes in fetal and maternal rabbit brain

1985 • 32 citations

Induction of constitutive heat shock protein 73 mRNA in the dentate gyrus by seizures

1992 • 27 citations

Isolation of major heat shock protein (hsp70) gene-related sequences from rat genome

1988 • 6 citations

Nucleotide sequence of a processed human hsc70 pseudogene

1987 • 4 citations