Human Gene Encoding the 78,000-Dalton Glucose-Regulated Protein and Its Pseudogene: Structure, Conservation, and Regulation

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

A C-terminal signal prevents secretion of luminal ER proteins

1987 • 2,189 citations

Speculations on the functions of the major heat shock and glucose-regulated proteins

1986 • 1,574 citations

An hsp70-like protein in the ER: Identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein

1986 • 1,457 citations

Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries.

1978 • 1,117 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas.

1986 • 896 citations

Expression of wild-type and mutant forms of influenza hemagglutinin: The role of folding in intracellular transport

1986 • 879 citations

Uncoating ATPase is a member of the 70 kilodalton family of stress proteins

1986 • 607 citations

Analysis of FBJ-MuSV provirus and c-fos (mouse) gene reveals that viral and cellular fos gene products have different carboxy termini

1983 • 532 citations

Human metallothionein genes—primary structure of the metallothionein-II gene and a related processed gene

1982 • 464 citations

Structure and expression of the human gene encoding major heat shock protein HSP70.

1985 • 461 citations

Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein.

1983 • 446 citations

Coordinated regulation of a set of genes by glucose and calcium ionophores in mammalian cells

1987 • 442 citations

Specific interaction between the p53 cellular tumour antigen and major heat shock proteins

1986 • 354 citations

Assembly and secretion of heavy chains that do not associate posttranslationally with immunoglobulin heavy chain-binding protein.

1987 • 343 citations

Nucleotide sequence divergence and functional constraint in mRNA evolution.

1980 • 249 citations

Processed genes: a dispersed human immunoglobulin gene bearing evidence of RNA-type processing

1982 • 235 citations

Cloning and expression of a gene encoding hsc73, the major hsp70-like protein in unstressed rat cells.

1987 • 193 citations

Evidence that a human β-tubulin pseudogene is derived from its corresponding mRNA

1982 • 177 citations

Highly conserved sequencim in the 3′ untranslated region of mRNAs coding for homologous proteins in distantly related species

1985 • 155 citations

Calcium ionophore A23187 induces expression of glucose-regulated genes and their heterologous fusion genes.

1985 • 146 citations

Rat gene encoding the 78-kDa glucose-regulated protein GRP78: its regulatory sequences and the effect of protein glycosylation on its expression.

1987 • 144 citations

Unusual evolutionary conservation and frequent DNA segment exchange in class I genes of the major histocompatibility complex.

1983 • 131 citations

Transcriptional regulation of two genes specifically induced by glucose starvation in a hamster mutant fibroblast cell line.

1983 • 128 citations

The accumulation of three specific proteins related to glucose‐regulated proteins in a temperature‐sensitive hamster mutant cell line K12

1981 • 125 citations

Calcium ionophore A23187 as a regulator of gene expression in mammalian cells.

1986 • 109 citations

Highly conserved glucose-regulated protein in hamster and chicken cells: preliminary characterization of its cDNA clone.

1981 • 102 citations

The nucleotide sequence encoding the hamster 78-kDa glucose-regulated protein (GRP78) and its conservation between hamster and rat

1987 • 93 citations

Induction of two genes by glucose starvation in hamster fibroblasts.

1984 • 82 citations

Isolation of temperature sensitive mammalian cells by selective detachment

1973 • 55 citations

A calcium ionophore-inducible cellular promoter is highly active and has enhancerlike properties.

1986 • 51 citations

Different rates of mRNA translation balance the expression of the two human alpha-globin loci.

1982 • 36 citations

Regulation of a Hybrid Gene by Glucose and Temperature in Hamster Fibroblasts

1984 • 35 citations

In cultured chick embryo fibroblasts the hexose transport components are not the 75 000 and 95 000 dalton polypeptides synthesized following glucose deprivation

1980 • 35 citations

Enhanced synthesis of the glucose/calcium‐regulated proteins in a hamster cell mutant deficient in transfer of oligosaccharide core to polypeptides

1986 • 31 citations

Molecular cloning of a steroid-regulated 108K beat shock protein gene from hen oviduct

1986 • 26 citations