Gain-of-function mutations in a human calmodulin-like protein identify residues critical for calmodulin action in yeast

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

1985 • 2,505 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

1984 • 2,401 citations

Yeast/E. coli shuttle vectors with multiple unique restriction sites

1986 • 1,399 citations

Laboratory course manual for methods in yeast genetics

1986 • 1,310 citations

Solution structure of a calmodulin-target peptide complex by multidimensional NMR

1992 • 1,258 citations

Target Enzyme Recognition by Calmodulin: 2.4 Å Structure of a Calmodulin-Peptide Complex

1992 • 1,031 citations

Structure of calmodulin refined at 2.2 Å resolution

1988 • 1,019 citations

Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae

1984 • 955 citations

How calmodulin binds its targets: sequence independent recognition of amphiphilic α-helices

1990 • 839 citations

Modulation of Calmodulin Plasticity in Molecular Recognition on the Basis of X-Ray Structures

1993 • 615 citations

Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae.

1984 • 462 citations

Isolation of the yeast calmodulin gene: Calmodulin is an essential protein

1986 • 400 citations

Can calmodulin function without binding calcium?

1991 • 318 citations

A rapid and convenient method for the preparation and storage of competent bacterial cells

1988 • 296 citations

Multiple divergent mRNAs code for a single human calmodulin.

1988 • 233 citations

The essential mitotic target of calmodulin is the 110-kilodalton component of the spindle pole body in Saccharomyces cerevisiae.

1993 • 145 citations

Diverse Essential Functions Revealed by Complementing Yeast Calmodulin Mutants

1994 • 142 citations

Site-specific mutagenesis of the alpha-helices of calmodulin. Effects of altering a charge cluster in the helix that links the two halves of calmodulin.

1987 • 135 citations

Multiple Ca2+/calmodulin-dependent protein kinase genes in a unicellular eukaryote.

1991 • 123 citations

Ca²⁺-Binding and Structural Dynamics in the Functions of Calmodulin

1994 • 118 citations

Conditions for reproducible detection of calmodulin and S100β in immunoblots

1984 • 116 citations

The unconventional myosin, Myo2p, is a calmodulin target at sites of cell growth in Saccharomyces cerevisiae

1994 • 109 citations

Molecular analysis of human and rat calmodulin complementary DNA clones. Evidence for additional active genes in these species.

1987 • 91 citations

Mutations in yeast calmodulin cause defects in spindle pole body functions and nuclear integrity.

1992 • 84 citations

Vertebrate and yeast calmodulin, despite significant sequence divergence, are functionally interchangeable.

1989 • 84 citations

Structure of Paramecium tetraurelia calmodulin at 1.8 Å resolution

1993 • 83 citations

A temperature-sensitive calmodulin mutant loses viability during mitosis.

1992 • 82 citations

Characterization of the human calmodulin-like protein expressed in Escherichia coli

1992 • 71 citations

Solution structure of calmodulin and its complex with a myosin light chain kinase fragment

1992 • 64 citations

Three amino acid substitutions in domain I of calmodulin prevent the activation of chicken smooth muscle myosin light chain kinase.

1991 • 62 citations

Down-regulation of a calmodulin-related gene during transformation of human mammary epithelial cells.

1990 • 53 citations

Extraction and rapid inactivation of proteins from Saccharomyces cerevisiae by trichloroacetic acid precipitation

1989 • 52 citations

Characterization of an intronless human calmodulin‐like pseudogene

1988 • 48 citations

The Essential Mitotic Target of Calmodulin is the 110-Kilodalton Component of the Spindle Pole Body in Saccharomyces cerevisiae

1993 • 48 citations

Taking a long, hard look at calmodulin's warm embrace

1994 • 41 citations

Functional expression of chicken calmodulin in yeast

1989 • 41 citations

Protein product of a human intronless calmodulin-like gene shows tissue-specific expression and reduced abundance in transformed cells.

1992 • 36 citations

Isolation and nucleotide sequence of a cDNA encoding human calmodulin.

1984 • 36 citations

Similarities and differences between yeast and vertebrate calmodulin: An examination of the calcium-binding and structural properties of calmodulin from the yeast Saccharomyces cerevisiae

1993 • 36 citations

Calmodulin.

1984 • 34 citations

Half-calmodulin is sufficient for cell proliferation. Expressions of N- and C-terminal halves of calmodulin in the yeast Saccharomyces cerevisiae.

1991 • 28 citations

Ca²⁺‐dependent ubiquitination of calmodulin in yeast

1992 • 27 citations

Role of domain 3 of calmodulin in activation of calmodulin-stimulated phosphodiesterase and smooth muscle myosin light chain kinase

1994 • 26 citations

Selective Activation and Inhibition of Calmodulin‐Dependent Enzymes by a Calmodulin‐Like Protein Found in Human Epithelial Cells

1994 • 26 citations

The linker of calmodulin — to helix or not to helix

1992 • 24 citations

Mutational analysis of calmodulin in Saccharomyces cerevisiae

1992 • 23 citations

Selective ubiquitination of calmodulin by UBC4 and a putative ubiquitin protein ligase (E3) from Saccharomyces cerevisiae

1993 • 16 citations

Functional consequences in yeast of single-residue alterations in a consensus calmodulin

1994 • 9 citations

Multifunctional Proteins: Calmodulin clarified

1994 • 3 citations

Deleted Work

1955 • 0 citations