Target Enzyme Recognition by Calmodulin: 2.4 Å Structure of a Calmodulin-Peptide Complex

Version 1.2 of the Crystallography and NMR system

2007 • 1,353 citations

Solution structure of a calmodulin-target peptide complex by multidimensional NMR

1992 • 1,258 citations

Structure of calmodulin refined at 2.2 Å resolution

1988 • 1,019 citations

How calmodulin binds its targets: sequence independent recognition of amphiphilic α-helices

1990 • 839 citations

Calmodulin

1982 • 771 citations

Calmodulin structure refined at 1.7 Å resolution

1992 • 709 citations

Ribbon models of macromolecules

1987 • 519 citations

Comparison of the crystal and solution structures of calmodulin and troponin C

1988 • 322 citations

Calmodulin binding domains: characterization of a phosphorylation and calmodulin binding site from myosin light chain kinase

1986 • 319 citations

Identification of the calmodulin-binding domain of skeletal muscle myosin light chain kinase.

1985 • 302 citations

Regulatory functions of calmodulin

1991 • 248 citations

The central helix of calmodulin functions as a flexible tether.

1988 • 245 citations

The calmodulin binding domain of chicken smooth muscle myosin light chain kinase contains a pseudosubstrate sequence.

1987 • 241 citations

The interaction of calmodulin with amphiphilic peptides.

1985 • 239 citations

Functional Analysis of a Complementary DNA for the 50-Kilodalton Subunit of Calmodulin Kinase II

1987 • 179 citations

Use of DNA sequence and mutant analyses and antisense oligodeoxynucleotides to examine the molecular basis of nonmuscle myosin light chain kinase autoinhibition, calmodulin recognition, and activity.

1990 • 167 citations

Autoregulation of Enzymes by Pseudosubstrate Prototopes: Myosin Light Chain Kinase

1988 • 152 citations

Triple-resonance multidimensional NMR study of calmodulin complexed with the binding domain of skeletal muscle myosin light-chain kinase: indication of a conformational change in the central helix

1991 • 143 citations

Interaction of calmodulin with the calmodulin binding domain of the plasma membrane calcium pump

1990 • 137 citations

The effects of deletions in the central helix of calmodulin on enzyme activation and peptide binding

1989 • 96 citations

Small-angle x-ray scattering study of calmodulin bound to two peptides corresponding to parts of the calmodulin-binding domain of the plasma membrane calcium pump

1991 • 95 citations

Photolabeling of Calmodulin with Basic, Amphiphilic α-Helical Peptides Containing p-Benzoylphenylalanine

1989 • 93 citations

Probable role of amphiphilicity in the binding of mastoparan to calmodulin

1985 • 79 citations

Functional significance of the central helix in calmodulin.

1988 • 71 citations

Identification of amino acids essential for calmodulin binding and activation of smooth muscle myosin light chain kinase.

1992 • 66 citations

Calmodulin activation of target enzymes. Consequences of deletions in the central helix.

1990 • 65 citations

Force display in molecular docking

1988 • 64 citations

Three amino acid substitutions in domain I of calmodulin prevent the activation of chicken smooth muscle myosin light chain kinase.

1991 • 62 citations

Model for the interaction of amphiphilic helices with troponin C and calmodulin

1990 • 59 citations

Definition of the inhibitory domain of smooth muscle myosin light chain kinase by site-directed mutagenesis

1991 • 50 citations

Effects of calcium binding on the internal dynamic properties of bovine brain calmodulin, studied by NMR and optical spectroscopy

1992 • 45 citations

Characterization of the secondary structure of calmodulin in complex with a calmodulin-binding domain peptide

1992 • 41 citations

Biochemical properties of chimeric skeletal and smooth muscle myosin light chain kinases.

1992 • 38 citations

Construction and molecular dynamics simulation of calmodulin in the extended and in a bent conformation

1992 • 26 citations

Calmodulin and Calmodulin-regulated Protein Kinases as Transducers of Intracellular Calcium Signals

1988 • 24 citations