Deletion of a HoxD enhancer induces transcriptional heterochrony leading to transposition of the sacrum

Hox genes in vertebrate development

1994 • 2,057 citations

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

1985 • 1,983 citations

Traite de zoologie

1955 • 941 citations

Altered Hox expression and segmental identity in Mll-mutant mice

1995 • 871 citations

Hox genes and the evolution of vertebrate axial morphology

1995 • 825 citations

Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene.

1994 • 775 citations

Homeotic genes and the evolution of arthropods and chordates

1995 • 737 citations

Temporal colinearity and the phylotypic progression: a basis for the stability of a vertebrate Bauplan and the evolution of morphologies through heterochrony

1994 • 631 citations

Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formation

1989 • 612 citations

Absence of radius and ulna in mice lacking hoxa-11 andhoxd-11

1995 • 587 citations

Know Your Neighbors: Three Phenotypes in Null Mutants of the Myogenic bHLH Gene MRF4

1996 • 572 citations

Altered segmental identity and abnormal migration of motor neurons in mice lacking Hoxb-1

1996 • 410 citations

Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes

1995 • 350 citations

Murine genes related to the Drosophila AbdB homeotic genes are sequentially expressed during development of the posterior part of the body.

1991 • 344 citations

In vivo functional analysis of the Hoxa-1 3′ retinoic acid response element (3′ RARE)

1997 • 333 citations

Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression.

1991 • 286 citations

Positive cross-regulation and enhancer sharing: two mechanisms for specifying overlapping Hox expression patterns.

1997 • 272 citations

Homeotic transformations and limb defects in Hox A11 mutant mice.

1993 • 260 citations

Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning

1996 • 259 citations

Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11

1994 • 253 citations

Identification of Bmi1-interacting proteins as constituents of a multimeric mammalian polycomb complex.

1997 • 240 citations

A mutational analysis of the 5′ HoxD genes: dissection of genetic interactions during limb development in the mouse

1996 • 229 citations

Gene Transpositions in the HoxD Complex Reveal a Hierarchy of Regulatory Controls

1996 • 226 citations

Synpolydactyly in mice with a targeted deficiency in the HoxD complex

1996 • 210 citations

The origin of vertebrate limbs

1994 • 202 citations

Transcriptional enhancers act in cis to suppress position-effect variegation.

1996 • 187 citations

Two gene members of the murine HOX-5 complex show regional and cell-type specific expression in developing limbs and gonads.

1989 • 176 citations

The vertebrate limb: A model system to study the Hox/hom gene network during development and evolution

1992 • 175 citations

Function of posterior HoxD genes in the morphogenesis of the anal sphincter

1996 • 174 citations

Transformation of axial skeleton due to overexpression of bmi-1 in transgenic mice

1995 • 155 citations

Functional cooperation between the non-paralogous genes Hoxa-10 and Hoxd-11 in the developing forelimb and axial skeleton

1996 • 154 citations

The Hox-4.8 gene is localized at the 5′ extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development

1991 • 135 citations

HOX4 genes encode transcription factors with potential auto- and cross-regulatory capacities.

1991 • 130 citations

Homoeobox gene expression in mouse embryos varies with position by the primitive streak stage

1986 • 126 citations

How the Hox gene Ultrabithorax specifies two different segments: the significance of spatial and temporal regulation within metameres

1995 • 125 citations

Conservation in the Hox code during morphological evolution.

1994 • 117 citations

Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice.

1995 • 107 citations

Two Phases in the Establishment of HOX Expression Domains

1993 • 105 citations

In vivo targeted mutagenesis of a regulatory element required for positioning the Hoxd-11 and Hoxd-10 expression boundaries.

1996 • 100 citations

Temporal colinearity in expression of anterior hox genes in developing chick embryos

1996 • 89 citations

Structure and activity of regulatory elements involved in the activation of the Hoxd-11 gene during late gastrulation.

1993 • 75 citations

Insertion of a targeting construct in a Hoxd‐10 allele can influence the control of Hoxd‐9 expression

1994 • 74 citations

Forward spreading in the establishment of a vertebrate Hox expression boundary: The expression domain separates into anterior and posterior zones, and the spread occurs across implanted glass barriers

1994 • 67 citations

A conserved enhancer of the human and murine Hoxa-7 gene specifies the anterior boundary of expression during embryonal development

1995 • 63 citations

Functional Equivalence and Rescue Among Group 11HoxGene Products in Vertebral Patterning

1996 • 57 citations

Combinations of closely situated cis-acting elements determine tissue-specific patterns and anterior extent of early Hoxc8 expression.

1996 • 55 citations

Function of the Evx-2 gene in the morphogenesis of vertebrate limbs.

1996 • 53 citations

Proximal cis-acting elements cooperate to set Hoxb-7 (Hox-2.3) expression boundaries in transgenic mice

1993 • 48 citations

Numerical significance in the thoracicolumbar vertebrae of the mammalia

1922 • 45 citations