The vertebrate limb: A model system to study the Hox/hom gene network during development and evolution

A gene complex controlling segmentation in Drosophila

1978 • 3,668 citations

Epithelial-Mesenchymal Interactions

1967 • 1,218 citations

The murine and Drosophila homeobox gene complexes have common features of organization and expression

1989 • 1,021 citations

Neural Crest and the Origin of Vertebrates: A New Head

1983 • 1,011 citations

Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid

1991 • 1,007 citations

The structure and function of the homeodomain

1989 • 1,007 citations

Identification and spatial distribution of retinoids in the developing chick limb bud

1987 • 964 citations

The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes.

1989 • 912 citations

Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5

1991 • 856 citations

Positional Information in Chick Limb Morphogenesis

1973 • 718 citations

Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression

1991 • 698 citations

Vertebrate Limb and Somite Morphogenesis

1979 • 613 citations

Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formation

1989 • 612 citations

A Morphogenetic Approach to the Origin and Basic Organization of the Tetrapod Limb

1986 • 604 citations

Murine Developmental Control Genes

1990 • 594 citations

Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells

1990 • 524 citations

A distinct Hox code for the branchial region of the vertebrate head

1991 • 503 citations

Retinoids, homeoboxes, and growth factors: Toward molecular models for limb development

1991 • 410 citations

Expression of the homeobox Hox-4 genes and the specification of position in chick wing development

1991 • 394 citations

Imprinting a determined state into the chromatin of Drosophila

1990 • 391 citations

Variations of cervical vertebrate after expression of a Hox-1.1 transgene in mice

1990 • 371 citations

Molecular and Genetic Organization of The Antennapedia Gene Complex of Drosophila melanogaster

1990 • 360 citations

The cellular basis of segmentation in the developing hindbrain

1990 • 358 citations

Murine genes related to the Drosophila AbdB homeotic genes are sequentially expressed during development of the posterior part of the body.

1991 • 344 citations

Positional information revisited

1989 • 322 citations

Homeobox gene expression correlated with the bifurcation process of limb cartilage development

1991 • 317 citations

HOX-4 genes and the morphogenesis of mammalian genitalia.

1991 • 292 citations

Ten different Polycomb group genes are required for spatial control of the abdA and AbdB homeotic products

1992 • 292 citations

Differential regulation by retinoic acid of the homeobox genes of the four HOX loci in human embryonal carcinoma cells

1991 • 291 citations

Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression.

1991 • 286 citations

Segment‐related, mosaic neurogenetic pattern in the forebrain and mesencephalon of early chick embryos: I. Topography of ache‐positive neuroblasts up to stage HH18

1987 • 257 citations

Spatially restricted domains of homeo-gene transcripts in mouse embryos: relation to a segmented body plan

1988 • 245 citations

Spatial mechanisms of gene regulation in metazoan embryos

1991 • 227 citations

A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation.

1990 • 225 citations

Involvement of the Chox-4 chicken homeobox genes in determination of anteroposterior axial polarity during limb development

1991 • 223 citations

Two steps in the evolution of Antennapedia-class vertebrate homeobox genes.

1989 • 212 citations

HOX gene activation by retinoic acid

1991 • 211 citations

The molecular genetics of the bithorax complex of Drosophila: cis-regulation in the Abdominal-B domain.

1990 • 197 citations

Mouse homeo-genes within a subfamily, Hox-1.4, -2.6 and -5.1, display similar anteroposterior domains of expression in the embryo, but show stage- and tissue-dependent differences in their regulation

1989 • 192 citations

The bithorax complex: control of segmental identity

1987 • 188 citations

Two gene members of the murine HOX-5 complex show regional and cell-type specific expression in developing limbs and gonads.

1989 • 176 citations

A deficiency of the homeotic complex of the beetle Tribolium

1991 • 157 citations

The Hox-4.8 gene is localized at the 5′ extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development

1991 • 135 citations

Molecular approaches to the segmentation of the hindbrain

1990 • 135 citations

HOX4 genes encode transcription factors with potential auto- and cross-regulatory capacities.

1991 • 130 citations

A homoeotic gene cluster in the red flour beetle

1987 • 127 citations

Analysis of the murine Hox-2.7 gene: conserved alternative transcripts with differential distributions in the nervous system and the potential for shared regulatory regions.

1992 • 123 citations

Patterning in the vertebrate limb

1991 • 114 citations

Positional signalling by Hensen’s node when grafted to the chick limb bud

1986 • 110 citations

Homeogene expression patterns and chromosomal imprinting.

1990 • 104 citations

Control of the expression of the bithorax complex genes abdominal-A and Abdominal-B by c/s-regulatory regions in Drosophila embryos

1991 • 101 citations

The mouse Hox-1.4 gene: primary structure, evidence for promoter activity and expression during development

1989 • 100 citations

Segmental expression of an engrailed-class gene during early development and neurogenesis in an annelid

1991 • 99 citations

Expression patterns of mouse hox genes: Clues to an understanding of developmental and evolutionary strategies

1991 • 92 citations

Overexpression of a homeodomain protein confers axis-forming activity to uncommitted xenopus embryonic cells

1991 • 88 citations

Developmental and evolutionary implications of labial, Deformed and engrailed expression in the Drosophila head

1991 • 85 citations

Primary structure and embryonic expression pattern of the mouse Hox-4.3* homeobox gene

1990 • 80 citations

Isolation of an abdominal-A gene from the locust Schistocerca gregaria and its expression during early embryogenesis

1990 • 75 citations

Retinoic acid and chick limb bud development

1991 • 74 citations

Cellular Mechanisms of Pattern Formation in the Developing Limb

1991 • 73 citations

Nematode homeobox cluster

1991 • 71 citations

Mechanisms of Transcriptional Timing in Drosophila

1992 • 46 citations

Hox-4 gene expression in mouse/chicken heterospecific grafts of signalling regions to limb buds reveals similarities in patterning mechanisms

1992 • 45 citations

Rescue and regulation of proboscipedia: a homeotic gene of the Antennapedia Complex

1991 • 36 citations

Neurulation in the mouse I. The ontogenesis of neural segments and the determination of topographical regions in a central nervous system

1987 • 30 citations

Craniofacial growth, evolutionary questions

1988 • 26 citations

A phylogenetic interpretation of the patterns of gene expression in Drosophila embryos

1988 • 18 citations