In vivo targeted mutagenesis of a regulatory element required for positioning the Hoxd-11 and Hoxd-10 expression boundaries.

The RXR heterodimers and orphan receptors

1995 • 3,168 citations

Hox genes in vertebrate development

1994 • 2,057 citations

Altering the Genome by Homologous Recombination

1989 • 2,021 citations

Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid

1991 • 1,007 citations

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1993 • 984 citations

Multiplicity generates diversity in the retinoic acid signalling pathways

1992 • 836 citations

Function of the retinoic acid receptors (RARs) during development: (I) Craniofacial and skeletal abnormalities in RAR double mutants

1994 • 755 citations

A versatilein vivoandin vitroeukaryotic expression vector for protein engineering

1988 • 686 citations

Absence of radius and ulna in mice lacking hoxa-11 andhoxd-11

1995 • 587 citations

Gene targeting: a practical approach.

1993 • 585 citations

Know Your Neighbors: Three Phenotypes in Null Mutants of the Myogenic bHLH Gene MRF4

1996 • 572 citations

Retinoic acid receptors and cellular retinoid binding proteins : II. Their differential pattern of transcription during early morphogenesis in mouse embryos

1991 • 527 citations

Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs

1993 • 454 citations

Chicken ovalbumin upstream promoter transcription factor (COUP-TF) dimers bind to different GGTCA response elements, allowing COUP-TF to repress hormonal induction of the vitamin D3, thyroid hormone, and retinoic acid receptors.

1992 • 388 citations

Regulation of the Apolipoprotein AI Gene by ARP-1, a Novel Member of the Steroid Receptor Superfamily

1991 • 382 citations

Specific spatial and temporal distribution of retinoic acid receptor gamma transcripts during mouse embryogenesis

1990 • 351 citations

Murine genes related to the Drosophila AbdB homeotic genes are sequentially expressed during development of the posterior part of the body.

1991 • 344 citations

Developmental expression of murine retinoid X receptor (RXR) genes

1994 • 297 citations

Homeotic transformations and limb defects in Hox A11 mutant mice.

1993 • 260 citations

Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11

1994 • 253 citations

Gene Transpositions in the HoxD Complex Reveal a Hierarchy of Regulatory Controls

1996 • 226 citations

The patterns of binding of RAR, RXR and TR homo- and heterodimers to direct repeats are dictated by the binding specificites of the DNA binding domains.

1993 • 218 citations

Functional cooperation between the non-paralogous genes Hoxa-10 and Hoxd-11 in the developing forelimb and axial skeleton

1996 • 154 citations

Cloning and expression during development of three murine members of the COUP family of nuclear orphan receptors

1994 • 143 citations

Problems and paradigms: Hoemeobox genes in vertebrate evolution

1992 • 123 citations

Spatial regulation of homeobox gene fusions in the embryonic central nervous system of transgenic mice

1988 • 113 citations

Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice.

1995 • 107 citations

Structure and activity of regulatory elements involved in the activation of the Hoxd-11 gene during late gastrulation.

1993 • 75 citations

Comparison of mouse and human HOX-4 complexes defines conserved sequences involved in the regulation of Hox-4.4.

1992 • 65 citations

Pure and functionally homogeneous recombinant retinoid X receptor.

1994 • 62 citations

Functional Equivalence and Rescue Among Group 11HoxGene Products in Vertebral Patterning

1996 • 57 citations