Deltex1 Redirects Lymphoid Progenitors to the B Cell Lineage by Antagonizing Notch1

Notch Signaling: Cell Fate Control and Signal Integration in Development

1999 • 5,826 citations

Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow

1997 • 2,205 citations

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

1991 • 1,693 citations

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow.

1991 • 1,622 citations

Deficient T Cell Fate Specification in Mice with an Induced Inactivation of Notch1

1999 • 1,392 citations

Signalling downstream of activated mammalian Notch

1995 • 1,375 citations

Notch Signaling

1995 • 1,282 citations

Notch Signaling: From the Outside In

2000 • 958 citations

Notch1 Expression in Early Lymphopoiesis Influences B versus T Lineage Determination

1999 • 956 citations

Fringe is a glycosyltransferase that modifies Notch

2000 • 846 citations

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

1994 • 766 citations

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.

1996 • 717 citations

Glycosyltransferase activity of Fringe modulates Notch–Delta interactions

2000 • 686 citations

The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases

2000 • 634 citations

A histone deacetylase corepressor complex regulates the Notch signal transduction pathway

1998 • 587 citations

MAML1, a human homologue of Drosophila Mastermind, is a transcriptional co-activator for NOTCH receptors

2000 • 576 citations

Contact-Dependent Inhibition of Cortical Neurite Growth Mediated by Notch Signaling

1999 • 568 citations

LIN-12/Notch signaling: lessons from worms and flies

1998 • 545 citations

Truncated Mammalian Notch1 Activates CBF1/RBPJk-Repressed Genes by a Mechanism Resembling That of Epstein-Barr Virus EBNA2

1996 • 459 citations

Identification of the Earliest B Lineage Stage in Mouse Bone Marrow

1996 • 395 citations

Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway

1996 • 372 citations

Correlating Notch Signaling with Thymocyte Maturation

1998 • 350 citations

Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation.

1994 • 334 citations

Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats

1995 • 324 citations

Effect of deoxyguanosine on lymphopoiesis in the developing thymus rudiment in vitro: Application in the production of chimeric thymus rudiments

1982 • 324 citations

Notch1 Signaling Promotes the Maturation of CD4 and CD8 SP Thymocytes

2000 • 317 citations

CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex

1999 • 301 citations

Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development

2001 • 300 citations

Essential Roles for Ankyrin Repeat and Transactivation Domains in Induction of T-Cell Leukemia by Notch1

2000 • 284 citations

Notch Inhibition of E47 Supports the Existence of a Novel Signaling Pathway

1998 • 261 citations

NUMB Localizes in the Basal Cortex of Mitotic Avian Neuroepithelial Cells and Modulates Neuronal Differentiation by Binding to NOTCH-1

1999 • 256 citations

SKIP, a CBF1-Associated Protein, Interacts with the Ankyrin Repeat Domain of NotchIC To Facilitate NotchIC Function

2000 • 244 citations

sel-10, a negative regulator of lin-12 activity inCaenorhabditis elegans, encodes a member of the CDC4 family of proteins

1997 • 234 citations

The WWE domain: a common interaction module in protein ubiquitination and ADP ribosylation

2001 • 222 citations

Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway

1994 • 209 citations

Both E12 and E47 Allow Commitment to the B Cell Lineage

1997 • 209 citations

Roles of the ankyrin repeats and C-terminal region of the mouse Notch1 intracellular region

1998 • 203 citations

Subversion of the T/B Lineage Decision in the Thymus by Lunatic Fringe-Mediated Inhibition of Notch-1

2001 • 195 citations

Isolation and Functional Analysis of a cDNA for Human Jagged2, a Gene Encoding a Ligand for the Notch1 Receptor

1997 • 192 citations

LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway

2000 • 190 citations

Human deltex is a conserved regulator of Notch signalling

1998 • 189 citations

Notch1 Regulates Maturation of CD4+ and CD8+ Thymocytes by Modulating TCR Signal Strength

2001 • 182 citations

Modulated expression of notch1 during thymocyte development

1996 • 147 citations

Notch1 Deficiency Dissociates the Intrathymic Development of Dendritic Cells and T Cells

2000 • 143 citations

Commitment to the B Lymphoid Lineage Occurs before DH-JH Recombination

1999 • 135 citations

deltex, a locus interacting with the neurogenic genes, Notch, Delta and mastermind in Drosophila melanogaster.

1990 • 123 citations

A Common Pathway for Dendritic Cell and Early B Cell Development

2001 • 117 citations

Epstein-Barr virus immortalization: Notch2 interacts with CBF1 and blocks differentiation

1997 • 111 citations

Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis

2001 • 91 citations

Receptors and signals in early thymic selection

1995 • 90 citations

A member of the Notch group of interacting loci, deltex encodes a cytoplasmic basic protein.

1994 • 79 citations

Notch signaling in leukemia

2001 • 68 citations

Notchless encodes a novel WD40-repeat-containing protein that modulates Notch signaling activity

1998 • 66 citations

Deciphering the role of Notch signaling in lymphopoiesis

2002 • 61 citations

Selective Utilization of Basic Helix-Loop-Helix–Leucine Zipper Proteins at the Immunoglobulin Heavy-Chain Enhancer

1997 • 50 citations

A genetic analysis of deltex and its interaction with the Notch locus in Drosophila melanogaster.

1992 • 50 citations

Deleted Work

1955 • 0 citations