Regulatory T Cells Ameliorate Angiotensin II–Induced Cardiac Damage

Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies

2002 • 9,810 citations

Inflammation, Atherosclerosis, and Coronary Artery Disease

2005 • 8,367 citations

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

2005 • 2,667 citations

Hypertension in mice lacking the gene for endothelial nitric oxide synthase

1995 • 2,075 citations

Role of the T cell in the genesis of angiotensin II–induced hypertension and vascular dysfunction

2007 • 1,612 citations

Natural regulatory T cells control the development of atherosclerosis in mice

2006 • 1,037 citations

A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3

2005 • 957 citations

Limitation of Excessive Extracellular Matrix Turnover May Contribute to Survival Benefit of Spironolactone Therapy in Patients With Congestive Heart Failure

2000 • 928 citations

Increased left ventricular mass and hypertrophy are associated with increased risk for sudden death

1998 • 796 citations

Prognostic implications of left ventricular hypertrophy

2001 • 716 citations

Foxp3 in control of the regulatory T cell lineage

2007 • 690 citations

Inflammation and angiotensin II

2003 • 676 citations

Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney

2006 • 663 citations

Natural Recovery and Protection from Autoimmune Encephalomyelitis: Contribution of CD4+CD25+ Regulatory Cells within the Central Nervous System

2005 • 545 citations

Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans

2007 • 516 citations

Cutting Edge: Human CD4+CD25+ T Cells Restrain the Maturation and Antigen-Presenting Function of Dendritic Cells

2004 • 472 citations

Elevated Blood Pressure and Risk of End-stage Renal Disease in Subjects Without Baseline Kidney Disease

2005 • 444 citations

NF-κB Inhibition Ameliorates Angiotensin II–Induced Inflammatory Damage in Rats

2000 • 404 citations

The Subpopulation of CD4+CD25+ Splenocytes That Delays Adoptive Transfer of Diabetes Expresses L-Selectin and High Levels of CCR7

2002 • 383 citations

Effective treatment of collagen‐induced arthritis by adoptive transfer of CD25+ regulatory T cells

2005 • 378 citations

Tumor Necrosis Factor-α Mediates Cardiac Remodeling and Ventricular Dysfunction After Pressure Overload State

2007 • 349 citations

Role of Naturally Occurring CD4 ⁺ CD25 ⁺ Regulatory T Cells in Experimental Atherosclerosis

2007 • 331 citations

CCR6 expression defines regulatory effector/memory-like cells within the CD25+CD4+ T-cell subset

2004 • 314 citations

Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway

1999 • 305 citations

Immunosuppressive Treatment Protects Against Angiotensin II-Induced Renal Damage

2002 • 273 citations

Human regulatory T cells and their role in autoimmune disease

2006 • 264 citations

Regression of Electrocardiographic Left Ventricular Hypertrophy During Antihypertensive Therapy and Reduction in Sudden Cardiac Death

2007 • 216 citations

Human T and Natural Killer Cells Possess a Functional Renin-Angiotensin System

2007 • 207 citations

Tregs and transplantation tolerance

2004 • 195 citations

Cellular Basis of Biventricular Hypertrophy and Arrhythmogenesis in Dogs With Chronic Complete Atrioventricular Block and Acquired Torsade de Pointes

1998 • 183 citations

Tregs and transplantation tolerance

2004 • 166 citations

The angiotensin-converting enzyme inhibitor, fosinopril, and the angiotensin II receptor antagonist, losartan, inhibit LDL oxidation and attenuate atherosclerosis independent of lowering blood pressure in apolipoprotein E deficient mice

1999 • 148 citations

Stimulation of lymphocyte responses by angiotensin II promotes kidney injury in hypertension

2008 • 145 citations

CD4+CD25+ Regulatory T Cells Protect against Injury in an Innate Murine Model of Chronic Kidney Disease

2006 • 132 citations

CD4⁺CD25⁺Regulatory T Cells and Their Therapeutic Potential

2005 • 126 citations

Complement Activation in Angiotensin II–Induced Organ Damage

2005 • 126 citations

Downregulation of connexin40 and increased prevalence of atrial arrhythmias in transgenic mice with cardiac-restricted overexpression of tumor necrosis factor

2006 • 119 citations

Is angiotensin II a proliferative factor of cardiac fibroblasts?

2002 • 114 citations

Aspirin inhibits NF‐κB and protects from angiotensin II‐induced organ damage

2001 • 101 citations

Foxp3-Transduced Polyclonal Regulatory T Cells Protect against Chronic Renal Injury from Adriamycin

2006 • 86 citations

Regression of Left Ventricular Hypertrophy With Captopril Restores Normal Ventricular Action Potential Duration, Dispersion of Refractoriness, and Vulnerability to Inducible Ventricular Fibrillation

1997 • 85 citations

Effect of Left Ventricular Hypertrophy and Its Regression on Ventricular Electrophysiology and Vulnerability to Inducible Arrhythmia in the Feline Heart

1995 • 82 citations

Cyclosporin A Protects Against Angiotensin II–Induced End-Organ Damage in Double Transgenic Rats Harboring Human Renin and Angiotensinogen Genes

2000 • 73 citations

A Pressor Response Associated with Drinking in Rats

1977 • 41 citations

Novel Role for Inhibitor of Differentiation 2 in the Genesis of Angiotensin II–Induced Hypertension

2008 • 34 citations

Inflammatory Biomarkers are not Predictive of Intermediate‐term Risk of Ventricular Tachyarrhythmias in Stable CHF Patients

2007 • 30 citations