Associative and motor learning in 12-month-old transgenic APP+PS1 mice

Neuropathological stageing of Alzheimer-related changes

1991 • 14,533 citations

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

1996 • 4,118 citations

Staging of alzheimer's disease-related neurofibrillary changes

1995 • 2,187 citations

Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

2000 • 1,498 citations

Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1

1996 • 1,439 citations

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1998 • 1,336 citations

The neurobiology of startle

1999 • 1,239 citations

Classical Conditioning and Brain Systems: The Role of Awareness

1998 • 1,091 citations

Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges

2001 • 1,048 citations

Cerebellum: Essential Involvement in the Classically Conditioned Eyelid Response

1984 • 902 citations

Amyloid β-Protein and the Genetics of Alzheimer's Disease

1996 • 794 citations

Fear-potentiated startle: A neural and pharmacological analysis

1993 • 736 citations

The Pathogenesis of Senile Plaques

1997 • 717 citations

Assessing the Validity of an Animal Model of Deficient Sensorimotor Gating in Schizophrenic Patients

1994 • 702 citations

The Relationship between Aβ and Memory in the Tg2576 Mouse Model of Alzheimer's Disease

2002 • 699 citations

Schizophrenia, Sensory Gating, and Nicotinic Receptors

1998 • 697 citations

Hippocampectomy disrupts trace eye-blink conditioning in rabbits.

2015 • 673 citations

Clinicopathologic Studies in Cognitively Healthy Aging and Alzheimer Disease

1998 • 641 citations

Toward a Comprehensive Theory for Alzheimer's Disease. Hypothesis: Alzheimer's Disease Is Caused by the Cerebral Accumulation and Cytotoxicity of Amyloid β‐Protein

2000 • 613 citations

Neural Substrates of Eyeblink Conditioning: Acquisition and Retention

2003 • 601 citations

Hippocampectomy disrupts trace eye-blink conditioning in rabbits.

1990 • 581 citations

Microglial response to amyloid plaques in APPsw transgenic mice.

1998 • 580 citations

Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes

2001 • 346 citations

Initial localization of the memory trace for a basic form of learning.

1982 • 332 citations

Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo.

1998 • 327 citations

Altered Activity in the Hippocampus Is More Detrimental to Classical Conditioning Than Removing the Structure

1983 • 312 citations

Antioxidant-rich diets improve cerebellar physiology and motor learning in aged rats

2000 • 306 citations

Relative Roles of Plaques and Tangles in the Dementia of Alzheimer's Disease: Correlations Using Three Sets of Neuropathological Criteria

1995 • 281 citations

Time Course of the Development of Alzheimer-like Pathology in the Doubly Transgenic PS1+APP Mouse

2002 • 245 citations

Sensitization of the acoustic startle reflex by footshock.

1989 • 233 citations

Age-Related Amyloid β Deposition in Transgenic Mice Overexpressing Both Alzheimer Mutant Presenilin 1 and Amyloid β Precursor Protein Swedish Mutant Is Not Associated with Global Neuronal Loss

2000 • 227 citations

Impaired classical eyeblink conditioning in cerebellar-lesioned and Purkinje cell degeneration (pcd) mutant mice.

1996 • 216 citations

Correlation between cognitive deficits and Aβ deposits in transgenic APP+PS1 mice

2001 • 199 citations

Reorganization of Cholinergic Terminals in the Cerebral Cortex and Hippocampus in Transgenic Mice Carrying Mutated Presenilin-1 and Amyloid Precursor Protein Transgenes

1999 • 196 citations

Amyloid Phenotype Characterization of Transgenic Mice Overexpressing both Mutant Amyloid Precursor Protein and Mutant Presenilin 1 Transgenes

1999 • 188 citations

Trace conditioning: Abolished by cerebellar nuclear lesions but not lateral cerebellar cortex aspirations

1985 • 187 citations

Impaired classical eyeblink conditioning in cerebellar-lesioned and Purkinje cell degeneration (pcd) mutant mice

1996 • 186 citations

Galantamine: Effect on nicotinic receptor binding, acetylcholinesterase inhibition, and learning

2001 • 177 citations

Multiple limbic regions mediate the disruption of prepulse inhibition produced in rats by the noncompetitive NMDA antagonist dizocilpine.

1998 • 165 citations

PET Imaging of Serotonin Type 2A Receptors in Late-Life Neuropsychiatric Disorders

1999 • 163 citations

Behavior and mutagenesis screens: the importance of baseline analysis of inbred strains

2000 • 158 citations

Multiple Limbic Regions Mediate the Disruption of Prepulse Inhibition Produced in Rats by the Noncompetitive NMDA Antagonist Dizocilpine

1998 • 148 citations

Medial prefrontal cortex and Pavlovian conditioning: Trace versus delay conditioning.

2002 • 132 citations

Behavioral Assessment of Alzheimer's Transgenic Mice Following Long-Term Aβ Vaccination: Task Specificity and Correlations between Aβ Deposition and Spatial Memory

2001 • 130 citations

Trace eyeblink conditioning is hippocampally dependent in mice

2003 • 130 citations

Deficient Sensorimotor Gating After 6‐Hydroxydopamine Lesion of the Rat medial Prefrontal Cortex is Reversed by Haloperidol

1994 • 128 citations

Eyeblink conditioning discriminates Alzheimerʼs patients from non-demented aged

1990 • 108 citations

Neuropathology of Mice Carrying Mutant APPswe and/or PS1M146L Transgenes: Alterations in the p75NTR Cholinergic Basal Forebrain Septohippocampal Pathway

2001 • 89 citations

Disruption of classical conditioning in patients with Alzheimer's disease

1991 • 87 citations

Asymmetric Interictal Glucose Hypometabolism and Cognitive Performance in Epileptic Patients

1994 • 83 citations

Impaired Eyeblink Conditioning and Decreased Hippocampal Volume in PDAPP V717F Mice

2002 • 75 citations

Fear conditioning to tone, but not to context, is attenuated by lesions of the insular cortex and posterior extension of the intralaminar complex in rats.

2001 • 71 citations

Eyeblink classical conditioning differentiates normal aging from Alzheimer’s disease

2001 • 71 citations

Scopolamine disruption of septo-hippocampal activity and classical conditioning.

1989 • 70 citations

Eyeblink classical conditioning in Alzheimer's disease and cerebrovascular dementia

1996 • 63 citations

Reduced corpus callosum, fornix and hippocampus in PDAPP transgenic mouse model of Alzheimer's disease

2001 • 61 citations

Scopolamine disruption of septo-hippocampal activity and classical conditioning.

1989 • 60 citations

Is there an optimal age for recovery from motor cortex lesions?

2000 • 58 citations

Alzheimer's disease and eyeblink conditioning: 750 ms trace vs. 400 ms delay paradigm

1996 • 54 citations

Motor coordination, exploration, and spatial learning in a natural mouse mutation (nervous) with Purkinje cell degeneration.

2003 • 49 citations

A general-purpose computer system for behavioral conditioning and neural recording experiments

1998 • 48 citations

Galantamine: Effect on nicotinic receptor binding, acetylcholinesterase inhibition, and learning

2001 • 41 citations

Age-Related Impairment in the 250-Millisecond Delay Eyeblink Classical Conditioning Procedure in C57BL/6 Mice

2002 • 35 citations

Extradural Compression of Sensorimotor Cortex: A Useful Model for Studies on Ischemic Brain Damage and Neuroprotection

2002 • 30 citations

Motor cortex lesions do not affect learning or performance of the eyeblink response in rabbits.

1997 • 26 citations

Cellular and molecular biology of alzheimer's disease

1989 • 25 citations

Motor cortex lesions do not affect learning or performance of the eyeblink response in rabbits.

1997 • 23 citations

Eyeblink Classical Conditioning in Alzheimer's Disease and Cerebrovascular Dementia

1996 • 23 citations

The effects of aging on cerebellar β-adrenergic receptor activation and motor learning in female F344 rats

1996 • 16 citations

Antioxidant protection of cerebellar β-adrenergic receptor function in aged F344 rats

1998 • 9 citations

Cortical Spreading Depression and Involvement of the Motor Cortex, Auditory Cortex, and Cerebellum in Eyeblink Classical Conditioning of the Rabbit

2002 • 7 citations

The effect of scopolamine in older rabbits tested in the 750 ms delay eyeblink classical conditioning procedure

2002 • 4 citations