The spectrum of spontaneous mutations in a Saccharomyces cerevisiae uracil-DNA-glycosylase mutant limits the function of this enzyme to cytosine deamination repair

High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules.

1979 • 1,504 citations

[10] 5-Fluoroorotic acid as a selective agent in yeast molecular genetics

1987 • 1,375 citations

A constant rate of spontaneous mutation in DNA-based microbes.

1991 • 1,194 citations

Heat-induced deamination of cytosine residues in deoxyribonucleic acid

1974 • 725 citations

DNA Mismatch Correction in a Defined System

1989 • 551 citations

A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy

1990 • 495 citations

Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines.

1990 • 408 citations

Transcription and processing of intervening sequences in yeast tRNA genes

1978 • 332 citations

Methyl-directed DNA Mismatch Correction

1989 • 297 citations

Spectra of spontaneous mutations in Escherichia coli strains defective in mismatch correction: the nature of in vivo DNA replication errors.

1987 • 291 citations

Initiation of SV40 DNA replication in vivo: Location and structure of 5′ ends of DNA synthesized in the ori region

1982 • 257 citations

Heteroduplex deoxyribonucleic acid base mismatch repair in bacteria

1986 • 252 citations

Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: homology of PMS1 to procaryotic MutL and HexB

1989 • 193 citations

The mutational specificity of DNA polymerases-alpha and -gamma during in vitro DNA synthesis.

1985 • 176 citations

Heteroduplex DNA correction in Saccharomyces cerevisiae is mismatch specific and requires functional PMS genes.

1989 • 164 citations

GATC sequences, DNA nicks and the MutH function in Escherichia coli mismatch repair.

1987 • 101 citations

Mechanisms of DNA-mismatch correction

1990 • 81 citations

Molecular cloning and primary structure of the uracil-DNA-glycosylase gene from Saccharomyces cerevisiae

1989 • 77 citations

The incorporation of uracil into animal cell DNA in vitro

1978 • 71 citations

Development of a yeast system to assay mutational specificity

1987 • 65 citations

Role of neighbouring bases and assessment of strand specificity in ethylmethanesulphonate and N-methyl-N′-nitro-N-nitrosoguanidine mutagenesis in the SUP4-o gene of Saccharomyces cerevisiae

1988 • 64 citations

Mismatch correction catalyzed by cell-free extracts of Saccharomyces cerevisiae.

1986 • 59 citations

DNA sequence analysis of spontaneous mutations in the SUP4-o gene of Saccharomyces cerevisiae.

1988 • 59 citations

Selection by genetic transformation of a Saccharomyces cerevisiae mutant defective for the nuclear uracil-DNA-glycosylase

1986 • 58 citations

Heteroduplex DNA Correction in Saccharomyces cerevisiae Is Mismatch Specific and Requires Functional PMS Genes

1989 • 56 citations

Asymmetric cytosine deamination revealed by spontaneous mutational specificity in an Ung− strain of Escherichia coli

1987 • 54 citations

Specificity of the mutator effect caused by disruption of the RAD1 excision repair gene of Saccharomyces cerevisiae

1990 • 44 citations

Isolation and characterization of the human uracil DNA glycosylase gene.

1989 • 36 citations

Uracil-DNA Glycosylases and DNA Uracil Repair

1989 • 26 citations

Role of uracil-DNA glycosylase in mutation avoidance by Streptococcus pneumoniae

1991 • 23 citations

DNA Sequence Analysis of Spontaneous Mutations in the SUP4-o Gene of Saccharomyces cerevisiae

1988 • 16 citations

Changes in the size of pulse-labelled DNA fragments induced in human cells by inhibitors of uracil-DNA glycosylase and DNA methylation

1989 • 1 citations