Nitric Oxide Involvement in Drosophila Immunity

Free radicals in biology and medicine

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1982 • 11,668 citations

Free Radicals in Biology and Medicine

1990 • 4,962 citations

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

1996 • 3,854 citations

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.

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Phylogenetic Perspectives in Innate Immunity

1999 • 2,478 citations

Redox signaling: Nitrosylation and related target interactions of nitric oxide

1994 • 1,732 citations

Nuclear Factor Kb: An Oxidative Stress-Responsive Transcription Factor of Eukaryotic Cells (A Review)

1992 • 1,421 citations

STATs: Signal Transducers and Activators of Transcription

1996 • 1,414 citations

Superoxide and hydrogen peroxide in relation to mammalian cell proliferation

1995 • 1,185 citations

Antimicrobial peptides in insects; structure and function

1999 • 1,001 citations

Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide

1992 • 702 citations

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense.

1995 • 590 citations

The roles of hydrogen peroxide and superoxide as messengers in the activation of transcription factor NF-κB

1995 • 460 citations

Identification of a Stat Gene That Functions in Drosophila Development

1996 • 397 citations

The mosquitoAnopheles stephensilimits malaria parasite development with inducible synthesis of nitric oxide

1998 • 394 citations

Jaks, STATs, Cytokine Signal Transduction, and Immunoregulation: Are We There Yet?

1997 • 381 citations

marelle Acts Downstream of the Drosophila HOP/JAK Kinase and Encodes a Protein Similar to the Mammalian STATs

1996 • 375 citations

Cell adhesion molecules and antioxidative enzymes in a crustacean, possible role in immunity

1999 • 372 citations

Cytotoxicity and cytotoxic molecules in invertebrates

2000 • 330 citations

Melanogenesis and the Generation of Cytotoxic Molecules During Insect Cellular Immune Reactions

1993 • 322 citations

Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila.

1994 • 308 citations

Superoxide anion generation in Drosophila during melanotic encapsulation of parasites.

1995 • 288 citations

The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense

1997 • 277 citations

Insect Ultrastructure

1984 • 273 citations

Immunity in Invertebrates

1986 • 271 citations

Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila.

1995 • 252 citations

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Oxygen and the control of gene expression

1994 • 245 citations

Drosophila cellular immunity against parasitoids

1997 • 219 citations

Multiple redox regulation in NF-kappaB transcription factor activation.

1997 • 215 citations

Anopheles gambiae Ag-STAT, a new insect member of the STAT family, is activated in response to bacterial infection

1999 • 210 citations

Antimicrobial peptide defense in Drosophila

1997 • 180 citations

Insect immunity: developmental and inducible activity of the Drosophila diptericin promoter.

1992 • 179 citations

Induction and regulation of antimicrobial peptides in Drosophila

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The Cellular Defense System of Drosophila melanogaster

1984 • 149 citations

Activation of NFκB by the respiratory burst of macrophages

1996 • 123 citations

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1989 • 111 citations

Evidence for nitric oxide production and utilization as a bacteriocidal agent by invertebrate immunocytes

1993 • 110 citations

l(1)hopscotch, a larval-pupal zygotic lethal with a specific maternal effect on segmentation in Drosophila

1986 • 108 citations

Nitric oxide synthase activity in molluscan hemocytes

1995 • 103 citations

Reactive oxygen intermediates as second messengers of a general pathogen response.

1996 • 98 citations

Hydrogen Peroxide Production in Immune-Reactive Drosophila melanogaster

1998 • 97 citations

Hydroxyl radical formation resulting from the interaction of nitric oxide and hydrogen peroxide

1998 • 92 citations

Nitric oxide in invertebrates

1998 • 84 citations

Identification of Hydrogen Peroxide as the Relevant Messenger in the Activation Pathway of Transcription Factor NF-κB

1996 • 75 citations

Free Radical Reactions in Medicine

1987 • 63 citations

Phylogenetic Perspectives on the Vertebrate Immune System

2001 • 61 citations

Nitric oxide: An ancestral immunocyte effector molecule

1995 • 56 citations

A new theory on the common evolutionary origin of natural immunity, inflammation and stress response: the invertebrate phagocytic immunocyte as an eye-witness

1998 • 54 citations

Expression of antimicrobial peptide genes after infection by parasitoid wasps in Drosophila

1996 • 35 citations

Differential induction of antibacterial transcripts in Drosophila susceptible and resistant to parasitism by Leptopilina boulardi

1996 • 25 citations

Cellular Immune Responses and Their Genetic Aspects in Drosophila

1986 • 25 citations

Insect immunity: A genetic factor (hrtp) is essential for antibacterial peptide expression inDrosophila after infection by parasitoid wasps

2000 • 18 citations