Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

Mutations affecting segment number and polarity in Drosophila

1980 • 4,280 citations

A gene complex controlling segmentation in Drosophila

1978 • 3,668 citations

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

The embryonic development of Drosophila melanogaster

1938 • 2,188 citations

SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins

1991 • 1,931 citations

Drosophila — A Practical Approach

1987 • 1,888 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

The Embryonic Development of Drosophila melanogaster

1985 • 1,371 citations

The origin of pattern and polarity in the Drosophila embryo

1992 • 1,367 citations

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

1993 • 1,223 citations

The molecular genetics of embryonic pattern formation in Drosophila

1988 • 1,048 citations

The molecular basis for metameric pattern in the Drosophila embryo

1987 • 1,028 citations

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

1993 • 988 citations

A protein tyrosine kinase in the interferon αβ signaling pathway

1992 • 876 citations

Determination of Anteroposterior Polarity in Drosophila

1987 • 651 citations

Vectors for Drosophila P-element-mediated transformation and tissue culture transfection

1988 • 547 citations

Regulation of even-skipped stripe 2 in the Drosophila embryo.

1992 • 522 citations

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.

1993 • 516 citations

Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase.

1991 • 499 citations

Use of a yeast site-specific recombinase to produce female germline chimeras in Drosophila.

1992 • 484 citations

Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro.

1989 • 484 citations

The engrailed locus of drosophila: In situ localization of transcripts reveals compartment-specific expression

1985 • 456 citations

Molecular cloning of sequences from wingless , a segment polarity gene in Drosophila : the spatial distribution of a transcript in embryos

1987 • 437 citations

Isolation, structure, and expression of even-skipped: A second pair-rule gene of Drosophila containing a homeo box

1986 • 380 citations

A transcription factor with SH2 and SH3 domains is directly activated by an interferon α-induced cytoplasmic protein tyrosine kinase(s)

1992 • 378 citations

Spatial distribution of transcripts from the segmentation gene fushi tarazu during Drosophila embryonic development

1984 • 369 citations

Regulation of the Drosophila segmentation gene hunchback by two maternal morphogenetic centres

1988 • 366 citations

Sequence analysis and neuronal expression of fasciclin I in grasshopper and drosophila

1988 • 363 citations

The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily

1990 • 361 citations

Transcriptional regulation of a pair-rule stripe in Drosophila.

1991 • 354 citations

Nuclear location signals in polyoma virus large-T

1986 • 351 citations

Isolation of a homoeo box-containing gene from the engrailed region of Drosophila and the spatial distribution of its transcripts

1985 • 346 citations

tyk2, prototype of a novel class of non-receptor tyrosine kinase genes.

1990 • 322 citations

Regulation of a Segmentation Stripe by Overlapping Activators and Repressors in the Drosophila Embryo

1991 • 321 citations

Interferon-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator.

1990 • 321 citations

JAK2, a third member of the JAK family of protein tyrosine kinases.

1992 • 306 citations

The Drosophila segmentation gene runt encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system.

1990 • 299 citations

Early and late periodic patterns of even skipped expression are controlled by distinct regulatory elements that respond to different spatial cues

1989 • 273 citations

Sequence-specific DNA-binding activities of the gap proteins encoded by hunchback and Krüppel in Drosophila

1989 • 270 citations

Autoregulatory and gap gene response elements of the even-skipped promoter of Drosophila.

1989 • 254 citations

The Drosophila Polycomb-group gene Enhancer of zeste contains a region with sequence similarity to trithorax.

1993 • 235 citations

Analysis of Krüppel protein distribution during early Drosophila development reveals posttranscriptional regulation

1987 • 222 citations

Establishment and refinement of segmental pattern in the Drosophila embryo: spatial control of engrailed expression by pair-rule genes.

1987 • 220 citations

Two Gap Genes Mediate Maternal Terminal Pattern Information in Drosophila

1990 • 214 citations

Zygotic lethals with specific maternal effect phenotypes in Drosophila melanogaster. I. Loci on the X chromosome.

1989 • 200 citations

Regulation of segment polarity genes in the Drosophila blastoderm by fushi tarazu and even skipped

1988 • 194 citations

Mobilization of hobo elements residing within the decapentaplegic gene complex: Suggestion of a new hybrid dysgenesis system in Drosophila melanogaster

1987 • 190 citations

Nucleotide sequences of feline retroviral oncogenes (v-fes) provide evidence for a family of tyrosine-specific protein kinase genes

1982 • 188 citations

Molecular cloning of the lethal(1)discs large-1 oncogene of Drosophila

1989 • 176 citations

Accurate measurements of dynamics and reproducibility in small genetic networks

2013 • 174 citations

Pentapeptide nuclear localization signal in adenovirus E1a.

1987 • 165 citations

Spatial regulation of the gap gene giant during Drosophila development

1991 • 157 citations

Hierarchical Inductions of Cell States: A Model for Segmentation in Drosophila

1986 • 157 citations

Gradients of Krüppel and knirps gene products direct pair-rule gene stripe patterning in the posterior region of the drosophila embryo

1990 • 137 citations

Isolation of the Drosophila segmentation gene runt and analysis of its expression during embryogenesis.

1988 • 135 citations

Three hormone receptor-like Drosophila genes encode an identical DNA-binding finger.

1989 • 127 citations

Making stripes in the Drosophila embryo

1990 • 124 citations

A domain of SV40 capsid polypeptide VP1 that specifies migration into the cell nucleus.

1986 • 120 citations

Pattern formation in the Drosophila embryo: allocation of cells to parasegments by even-skipped and fushi tarazu

1989 • 113 citations

l(1)hopscotch, a larval-pupal zygotic lethal with a specific maternal effect on segmentation in Drosophila

1986 • 108 citations

Knowing your neighbors: Cell interactions determine intrasegmental patterning in Drosophila

1992 • 86 citations

Characterization of elk, a brain-specific receptor tyrosine kinase.

1991 • 84 citations

polyhomeotic: a gene required for the embryonic development of axon pathways in the central nervous system of Drosophila.

1988 • 76 citations

Lethal(1)aberrant immune response mutations leading to melanotic tumor formation in Drosophila melanogaster

1991 • 75 citations

Localized requirements for gene activity in segmentation of Drosophila embryos: analysis of armadillo, fused, giant and unpaired mutations in mosaic embryos

1986 • 74 citations

Repression of Drosophila pair-rule segmentation genes by ectopic expression of tramtrack

1993 • 70 citations

Control of segmental asymmetry in Drosophila embryos

1993 • 68 citations

Drosophila Krüppel gene product produced in a baculovirus expression system is a nuclear phosphoprotein that binds to DNA.

1987 • 67 citations

The egg came first, of course!

1989 • 49 citations

Effects of dmso on vacuole formation, contractile vacuole function, and nuclear division in Tetrahymena Pyriformis GL

1974 • 39 citations

Transcriptional control by Drosophila gap genes

1992 • 32 citations

Stage-specific phosphorylation of the fushi tarazu protein during Drosophila development.

1989 • 26 citations