A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense.

Innate immunity of insects

1995 • 549 citations

Sequence, structure, and codon preference of theDrosophilaribosomal protein 49 gene

1984 • 523 citations

Vectors for P element-mediated gene transfer inDrosophila

1983 • 491 citations

Dif, a dorsal-related gene that mediates an immune response in Drosophila

1993 • 464 citations

Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides

1994 • 439 citations

Immune reactions in Drosophila and other insects: a model for innate immunity

1993 • 417 citations

A novel inducible antibacterial peptide of Drosophila carries an O-glycosylated substitution

1993 • 364 citations

The cecropin locus in Drosophila; a compact gene cluster involved in the response to infection.

1990 • 271 citations

Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila.

1995 • 252 citations

κB-like Motifs Regulate the Induction of Immune Genes in Drosophila

1993 • 229 citations

Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin

1994 • 183 citations

Insect immunity: developmental and inducible activity of the Drosophila diptericin promoter.

1992 • 179 citations

Insect immunity. Characterization of a Drosophila cDNA encoding a novel member of the diptericin family of immune peptides.

1990 • 178 citations

Insect immunity. Two 17 bp repeats nesting a kappa B-related sequence confer inducibility to the diptericin gene and bind a polypeptide in bacteria-challenged Drosophila.

1993 • 159 citations

CecC, a cecropin gene expressed during metamorphosis in Drosophila pupae

1992 • 107 citations

Expression and nuclear translocation of the rel/NF-kappa B-related morphogen dorsal during the immune response of Drosophila.

1993 • 89 citations

Insect immunity. A transgenic analysis in Drosophila defines several functional domains in the diptericin promoter.

1994 • 83 citations

Insect Immunity: The Diptericin Promoter Contains Multiple Functional Regulatory Sequences Homologous to Mammalian Acute-Phase Response Elements

1993 • 62 citations

P regulatory products repress in vivo the P promoter activity in P-lacZ fusion genes.

1991 • 51 citations

Molecular genetics of Drosophila immunity

1994 • 44 citations