Bone Turnover in Prolonged Critical Illness: Effect of Vitamin D

APACHE II-A Severity of Disease Classification System

1986 • 12,607 citations

Intensive Insulin Therapy in Critically Ill Patients

2001 • 9,943 citations

Vitamin D₃and Calcium to Prevent Hip Fractures in Elderly Women

1992 • 2,963 citations

Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis*

2000 • 2,226 citations

Vitamin D Deficiency and Secondary Hyperparathyroidism in the Elderly: Consequences for Bone Loss and Fractures and Therapeutic Implications

2001 • 1,911 citations

Progressive development of the rat osteoblast phenotype in vitro: Reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix

1990 • 1,546 citations

Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety

1999 • 1,500 citations

Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride

1997 • 1,443 citations

Increased Osteoclast Development After Estrogen Loss: Mediation by Interleukin-6

1992 • 1,437 citations

TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand

2000 • 1,330 citations

Structure-Function Relationships in the Vitamin D Endocrine System*

1995 • 1,182 citations

Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis

2000 • 1,175 citations

Guidelines for the Use of Parenteral and Enteral Nutrition in Adult and Pediatric Patients

1993 • 886 citations

Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6.

1993 • 827 citations

Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion.

1994 • 738 citations

Vitamin D Deficiency and Secondary Hyperparathyroidism in the Elderly: Consequences for Bone Loss and Fractures and Therapeutic Implications

2001 • 544 citations

Influence of the Vitamin D-binding Protein on the Serum Concentration of 1,25-Dihydroxyvitamin D3

1981 • 507 citations

Mannose Receptor-Mediated Regulation of Serum Glycoprotein Homeostasis

2002 • 477 citations

The coming of age of 1,25-dihydroxyvitamin D3 analogs as immunomodulatory agents

2002 • 469 citations

The Effects of Twelve Weeks of Bed Rest on Bone Histology, Biochemical Markers of Bone Turnover, and Calcium Homeostasis in Eleven Normal Subjects

1998 • 367 citations

Acute and Prolonged Critical Illness as Different Neuroendocrine Paradigms¹

1998 • 349 citations

Vitamin D-binding protein (Gc-globulin) binds actin.

1980 • 278 citations

Structure-function relationships in the vitamin D endocrine system

1995 • 268 citations

Interleukin-6 enhances hypercalcemia and bone resorption mediated by parathyroid hormone-related protein in vivo.

1995 • 260 citations

Vitamin D status in the elderly: seasonal substrate deficiency causes 1,25-dihydroxycholecalciferol deficiency

1987 • 240 citations

Reactivation of Pituitary Hormone Release and Metabolic Improvement by Infusion of Growth Hormone-Releasing Peptide and Thyrotropin-Releasing Hormone in Patients with Protracted Critical Illness1

1999 • 227 citations

Metabolic Bone Disease in Patients Receiving Long-Term Total Parenteral Nutrition

1980 • 211 citations

Calcium and vitamin D

2003 • 183 citations

Apoptosis during bone-like tissue development in vitro

1998 • 180 citations

Measurement of Bone Collagen Degradation in Hyperthyroidism and During Thyroxine Replacement Therapy Using Pyridinium Cross-Links as Specific Urinary Markers*

1991 • 153 citations

Urinary hydroxypyridinium cross-links of collagen in primary hyperparathyroidism.

1992 • 143 citations

Osteoclasts expressing the measles virus nucleocapsid gene display a pagetic phenotype

2000 • 139 citations

Age-Related (Type II) Femoral Neck Osteoporosis in Men: Biochemical Evidence for Both Hypovitaminosis D– and Androgen Deficiency–Induced Bone Resorption

1997 • 131 citations

The combined administration of GH‐releasing peptide‐2 (GHRP‐2), TRH and GnRH to men with prolonged critical illness evokes superior endocrine and metabolic effects compared to treatment with GHRP‐2 alone

2002 • 128 citations

Space Flight: A Challenge for Normal Bone Homeostasis

2001 • 120 citations

Biochemical Markers of Bone Resorption Compared with Estimates of Bone Resorption from Radiotracer Kinetic Studies in Osteoporosis

1997 • 116 citations

Vitamin D3 and Calcium to Prevent Hip Fractures in Elderly Women

1993 • 115 citations

Five-Day Pulsatile Gonadotropin-Releasing Hormone Administration Unveils Combined Hypothalamic-Pituitary-Gonadal Defects Underlying Profound Hypoandrogenism in Men with Prolonged Critical Illness1

2001 • 112 citations

The vitamin D receptor is necessary for 1α,25-dihydroxyvitamin D3 to suppress experimental autoimmune encephalomyelitis in mice

2002 • 111 citations

A Possible Role of Vitamin D in the Genesis of Parenteral-Nutrition-Induced Metabolic Bone Disease

1981 • 109 citations

Immunoradiometric assay of parathyrin with polyclonal and monoclonal region-specific antibodies

1990 • 104 citations

Bone Hyperresorption Is Prevalent in Chronically Critically III Patients

1998 • 98 citations

Osteopenia in Eugonadal Men with Acquired Immune Deficiency Syndrome Wasting Syndrome1

2001 • 92 citations

Biochemical markers of bone metabolism.

1991 • 80 citations

A Novel in Vivo Rabbit Model of Hypercatabolic Critical Illness Reveals a Biphasic Neuroendocrine Stress Response

2002 • 73 citations

Interleukin-6 antisense deoxyoligonucleotides inhibit bone resorption by giant cells from human giant cell tumors of bone

1994 • 68 citations

Lower mobility and markers of bone resorption in the elderly

1990 • 66 citations

Homologous Radioimmunoassay of Human Osteocalcin

1992 • 65 citations

Biochemical Response to Treatment of Bone Hyperresorption in Chronically Critically Ill Patients

2000 • 58 citations

92238400 Increased osteoclast development after estrogen loss: Mediation by interleukin-6

1993 • 55 citations

Role of group-specific component (vitamin D binding protein) in clearance of actin from the circulation in the rabbit.

1988 • 54 citations

Kaposi sarcoma is a therapeutic target for vitamin D3receptor agonist

2000 • 50 citations

Urinary hydroxypyridinium cross-links of collagen in primary hyperparathyroidism

1992 • 46 citations

Osteopenia in Eugonadal Men with Acquired Immune Deficiency Syndrome Wasting Syndrome

2001 • 41 citations

Admission level of Gc-globulin predicts outcome after multiple trauma

1999 • 41 citations

Vitamin D and Calcium: Recommended Intake for Bone Health

1998 • 40 citations

Humoral markers of severity and prognosis of critical illness

2001 • 37 citations

Increased bone resorption in the critically ill: Association with sepsis and increased nitric oxide production

2002 • 33 citations

A Novel in Vivo Rabbit Model of Hypercatabolic Critical Illness Reveals a Biphasic Neuroendocrine Stress Response

2002 • 25 citations

BIOCHEMICAL MARKERS OF BONE TURNOVER

1998 • 20 citations

Biochemical Markers of Bone Metabolism

2002 • 12 citations

Effect of bed rest immobilization on metabolic turnover of bone and bone mineral density.

1997 • 12 citations

Biochemical markers of bone turnover

2007 • 11 citations

Optimal Range of Plasma Concentration of True 1-84 Parathyroid Hormone in Patients on Maintenance Dialysis

2001 • 7 citations

Kaposi sarcoma is a therapeutic target for vitamin D3receptor agonist

2000 • 6 citations