Overexpression of the focal adhesion kinase (p125FAK) in the vascular smooth muscle cells of intimal hyperplasia

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

1992 • 1,456 citations

Kinetics of cellular proliferation after arterial injury. I. Smooth muscle growth in the absence of endothelium.

1983 • 1,441 citations

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly.

1992 • 1,330 citations

FAK integrates growth-factor and integrin signals to promote cell migration

2000 • 1,215 citations

Control of adhesion-dependent cell survival by focal adhesion kinase.

1996 • 1,113 citations

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin.

1992 • 811 citations

Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase.

1992 • 743 citations

Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets.

1992 • 669 citations

Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors.

1995 • 619 citations

Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn

1996 • 595 citations

Vascular Endothelial Growth Factor Stimulates Tyrosine Phosphorylation and Recruitment to New Focal Adhesions of Focal Adhesion Kinase and Paxillin in Endothelial Cells

1997 • 477 citations

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions.

1993 • 408 citations

Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes.

2000 • 407 citations

Inhibition of pp125FAK in cultured fibroblasts results in apoptosis.

1996 • 371 citations

Expression of focal adhesion kinase gene and invasive cancer

1993 • 335 citations

Role of focal adhesion kinase in integrin signaling

1997 • 331 citations

Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells.

1996 • 265 citations

Inhibition of vascular smooth muscle cell migration by heparin‐like glycosaminoglycans

1984 • 207 citations

Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer

1996 • 201 citations

The Focal Adhesion Kinase Suppresses Transformation-associated, Anchorage-independent Apoptosis in Human Breast Cancer Cells

2000 • 182 citations

Regulation of Smooth Muscle Cell Growth in Injured Artery

1989 • 167 citations

An overview of intimal hyperplasia.

1990 • 132 citations

Stimulation of phosphatidylinositol 3'-kinase association with foca adhesion kinase by platelet-derived growth factor.

1994 • 126 citations

Focal adhesion kinase is abundant in developing blood vessels and elevation of its phosphotyrosine content in vascular smooth muscle cells is a rapid response to angiotensin II

1994 • 122 citations

An Overview of Intimal Hyperplasia

1991 • 100 citations

Overexpression of focal adhesion kinase (p125FAK) in human colorectal carcinoma liver metastases: Independence from c-src or c-yes activation

1997 • 57 citations