Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells.

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Studies of the HER-2/ neu Proto-Oncogene in Human Breast and Ovarian Cancer

1989 • 6,734 citations

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

Disruption of epithelial cell-matrix interactions induces apoptosis

1994 • 3,167 citations

Social controls on cell survival and cell death

1992 • 2,641 citations

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly.

1992 • 1,330 citations

Anchorage dependence, integrins, and apoptosis

1994 • 1,016 citations

Apoptotic cell death induced by c-myc is inhibited by bcl-2

1992 • 981 citations

Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation

1992 • 831 citations

Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors.

1995 • 619 citations

Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells.

1994 • 439 citations

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions.

1993 • 408 citations

Expression of focal adhesion kinase gene and invasive cancer

1993 • 335 citations

Activation of pp60c-src protein kinase activity in human colon carcinoma.

1987 • 306 citations

Activation of the pp60c-src protein kinase is an early event in colonic carcinogenesis.

1990 • 280 citations

Flow cytometric detection of apoptosis: Comparison of the assays of in situ DNA degradation and chromatin changes

1994 • 235 citations

Stable Association of Activated pp60^src with Two Tyrosine-Phosphorylated Cellular Proteins

1989 • 168 citations

Human T and B Lymphocytes Express a Structurally Conserved Focal Adhesion Kinase, pp125^FAK

1993 • 91 citations

Antisense attenuation of Wnt‐1 and Wnt‐3a expression in whole embryo culture reveals roles for these genes in craniofacial, spinal cord, and cardiac morphogenesis

1993 • 90 citations

Expression of growth factor receptors, the focal adhesion kinase, and other tyrosine kinases in human soft tissue tumors

1994 • 89 citations

Identification of Apoptotic and Necrotic Human Leukemic Cells by Flow Cytometry

1994 • 50 citations