Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions.

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

Oncogenes and signal transduction

1991 • 2,816 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

Focal Adhesions: Transmembrane Junctions Between the Extracellular Matrix and the Cytoskeleton

1988 • 2,137 citations

Integrins and other cell adhesion molecules

1990 • 1,990 citations

Signal transduction from the extracellular matrix.

1993 • 1,727 citations

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

1992 • 1,456 citations

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly.

1992 • 1,330 citations

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1991 • 1,317 citations

Interaction of plasma membrane fibronectin receptor with talin—a transmembrane linkage

1986 • 1,206 citations

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.

1989 • 1,073 citations

ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain

1992 • 1,037 citations

SH2 and SH3 domains: From structure to function

1992 • 977 citations

A protein tyrosine kinase in the interferon αβ signaling pathway

1992 • 876 citations

An interaction between alpha-actinin and the beta 1 integrin subunit in vitro.

1990 • 851 citations

Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation

1992 • 831 citations

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin.

1992 • 811 citations

Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase.

1992 • 743 citations

Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins.

1991 • 713 citations

Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors

1987 • 651 citations

Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein.

1991 • 578 citations

T cell antigen receptor signal transduction: A tale of tails and cytoplasmic protein-tyrosine kinases

1993 • 552 citations

The when and how of Src regulation

1993 • 543 citations

Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase.

1991 • 499 citations

Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.

1990 • 480 citations

Molecular cloning of a porcine gene syk that encodes a 72-kDa protein-tyrosine kinase showing high susceptibility to proteolysis

1991 • 449 citations

Identification and characterization of a novel cytoskeleton-associated pp60src substrate.

1991 • 435 citations

[33] High-expression vectors with multiple cloning sites for construction of trpE fusion genes: pATH vectors

1991 • 350 citations

Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene.

1989 • 349 citations

Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

1991 • 348 citations

Zyxin and cCRP: two interactive LIM domain proteins associated with the cytoskeleton.

1992 • 344 citations

tyk2, prototype of a novel class of non-receptor tyrosine kinase genes.

1990 • 322 citations

An actin-binding function contributes to transformation by the Bcr-Abl oncoprotein of Philadelphia chromosome-positive human leukemias.

1993 • 317 citations

Autonomous Expression of a Noncatalytic Domain of the Focal Adhesion-Associated Protein Tyrosine Kinase pp125^FAK

1993 • 282 citations

Multiple elevations of cytosolic-free Ca2+ in human neutrophils: initiation by adherence receptors of the integrin family.

1991 • 259 citations

Integrins isolated from Rous sarcoma virus-transformed chicken embryo fibroblasts.

1989 • 256 citations

Presence of an SH2 Domain in the Actin-Binding Protein Tensin

1991 • 248 citations

Transmembrane molecular assemblies in cell-extracellular matrix interactions

1991 • 244 citations

Spreading of human endothelial cells on fibronectin or vitronectin triggers elevation of intracellular free calcium.

1993 • 242 citations

Role of platelet membrane glycoprotein IIb-IIIa in agonist-induced tyrosine phosphorylation of platelet proteins.

1990 • 237 citations

B lymphocyte activation is accompanied by phosphorylation of a 72-kDa protein-tyrosine kinase

1991 • 204 citations

Genetics of src: Structure and Functional Organization of a Protein Tyrosine Kinase

1989 • 197 citations

Tumor necrosis factor-induced degranulation in adherent human neutrophils is dependent on CD11b/CD18-integrin-triggered oscillations of cytosolic free Ca2+.

1990 • 180 citations

Focal adhesion kinase: an integrin-linked protein tyrosine kinase

1993 • 177 citations

Disruption of the actin cytoskeleton after microinjection of proteolytic fragments of alpha-actinin.

1991 • 165 citations

Monoclonal antibodies to Rous sarcoma virus pp60src react with enzymatically active cellular pp60src of avian and mammalian origin

1984 • 163 citations

Monoclonal antibodies specific for the carboxy terminus of simian virus 40 large T antigen

1984 • 163 citations

Tyrosine phosphorylation of the focal adhesion kinase pp125FAK during development: relation to paxillin

1993 • 139 citations

Two Novel Protein-Tyrosine Kinases, Each with a Second Phosphotransferase-Related Catalytic Domain, Define a New Class of Protein Kinase

1991 • 118 citations

Identification and Characterization of a Novel Cytoskeleton-Associated pp60^src Substrate

1991 • 113 citations

Expression of an N-Terminally Truncated Form of Human Focal Adhesion Kinase in Brain

1993 • 99 citations

Transformation-Specific Tyrosine Phosphorylation of a Novel Cellular Protein in Chicken Cells Expressing Oncogenic Variants of the Avian Cellular src Gene

1989 • 95 citations

Signal transduction by the platelet integrin alpha IIb beta 3: induction of calcium oscillations required for protein-tyrosine phosphorylation and ligand-induced spreading of stably transfected cells.

1992 • 95 citations

Identification of a talin binding site in the cytoskeletal protein vinculin.

1989 • 86 citations

Immunoaffinity purification of tyrosine-phosphorylated cellular proteins

1989 • 84 citations

Functional studies of the domains of talin.

1990 • 81 citations

Amino Acid Alterations Within a Highly Conserved Region of the Rous Sarcoma Virus src Gene Product pp60^src Inactivate Tyrosine Protein Kinase Activity

1984 • 75 citations

DNA sequence, structure, and tyrosine kinase activity of the Drosophila melanogaster Abelson proto-oncogene homolog.

1988 • 67 citations

Myristylation Is Required for Tyr-527 Dephosphorylation and Activation of pp60^c-src in Mitosis

1993 • 57 citations

Intracellular targeting of pp60src expression: localization of v-src to adhesion plaques is sufficient to transform chicken embryo fibroblasts.

1992 • 32 citations

DNA Sequence, Structure, and Tyrosine Kinase Activity of the Drosophila melanogaster Abelson Proto-Oncogene Homolog

1988 • 11 citations

Deleted Work

1955 • 0 citations

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