Helix formation and stability in a signal sequence

Computed circular dichroism spectra for the evaluation of protein conformation

1969 • 3,654 citations

A two-dimensional nuclear overhauser experiment with pure absorption phase in four quadrants

1982 • 2,567 citations

Conformational parameters for amino acids in helical, β-sheet, and random coil regions calculated from proteins

1974 • 2,173 citations

Determination of the helix and β form of proteins in aqueous solution by circular dichroism

1974 • 2,040 citations

A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules

1980 • 1,886 citations

Amino Acid Preferences for Specific Locations at the Ends of α Helices

1988 • 1,356 citations

Specific Intermediates in the Folding Reactions of Small Proteins and the Mechanism of Protein Folding

1982 • 1,041 citations

Calibration of the angular dependence of the amide proton-Cα proton coupling constants, 3JHNα, in a globular protein

1984 • 956 citations

Assignment of complex proton NMR spectra via two-dimensional homonuclear Hartmann-Hahn spectroscopy

1985 • 814 citations

Polypeptide secondary structure determination by nuclear magnetic resonance observation of short proton-proton distances

1984 • 756 citations

Two-dimensional chemical exchange and cross-relaxation spectroscopy of coupled nuclear spins

1981 • 754 citations

Homonuclear broad band decoupling and two-dimensional J-resolved NMR spectroscopy

1976 • 653 citations

Sequential resonance assignments in protein 1H nuclear magnetic resonance spectra

1982 • 585 citations

Correlation of competence for export with lack of tertiary structure of the mature species: A study in vivo of maltose-binding protein in E. coli

1986 • 473 citations

Conformation of peptide fragments of proteins in aqueous solution: implications for initiation of protein folding

1988 • 463 citations

Folding of immunogenic peptide fragments of proteins in water solution

1988 • 437 citations

Stabilization of the ribonuclease S‐peptide α‐helix by trifluoroethanol

1986 • 381 citations

A salt bridge stabilizes the helix formed by isolated C-peptide of RNase A.

1982 • 284 citations

A peptide model of a protein folding intermediate

1988 • 252 citations

Modulation of Folding Pathways of Exported Proteins by the Leader Sequence

1988 • 243 citations

Conformations of Signal Peptides Induced by Lipids Suggest Initial Steps in Protein Export

1986 • 225 citations

Molecular Mechanisms of Protein Secretion: The Role of the Signal Sequence

1986 • 222 citations

Persistence of the .alpha.-helix stop signal in the S-peptide in trifluoroethanol solutions

1989 • 212 citations

Protein unfolding and the energetics of protein translocation across biological membranes

1988 • 192 citations

Export of Protein: A Biochemical View

1987 • 184 citations

Circular Dichroism of Peptides

1985 • 162 citations

Two-dimensional J-resolved 1H n.m.r. spectroscopy for studies of biological macromolecules

1977 • 144 citations

In Vivo Function and Membrane Binding Properties Are Correlated for Escherichia coli lamB Signal Peptides

1985 • 130 citations

Exploring the conformational roles of signal sequences: synthesis and conformational analysis of .lambda. receptor protein wild-type and mutant signal peptides

1984 • 117 citations

Conformational studies of the synthetic precursor-specific region of preproparathyroid hormone.

1980 • 109 citations

Protein Translocation Across and Integration into Membrane

1986 • 91 citations

Penetration of the signal sequence of Escherichia coli PhoE protein into phospholipid model membranes leads to lipid-specific changes in signal peptide structure and alterations of lipid organization

1988 • 89 citations

Conformations and orientations of a signal peptide interacting with phospholipid monolayers

1989 • 78 citations

Characterization of the interfacial behavior and structure of the signal sequence of Escherichia coli outer membrane pore protein PhoE.

1988 • 72 citations

Physical and conformational properties of a synthetic leader peptide from M13 coat protein

1984 • 49 citations

Protein translocation into Escherichia coli membrane vesicles is inhibited by functional synthetic signal peptides.

1987 • 40 citations

Analysis of peptides for helical prediction

1989 • 36 citations