Conformational parameters for amino acids in helical, β-sheet, and random coil regions calculated from proteins

Prediction of protein conformation

1974 • 3,327 citations

Carp Muscle Calcium-binding Protein

1973 • 1,359 citations

Use of Helical Wheels to Represent the Structures of Proteins and to Identify Segments with Helical Potential

1967 • 1,178 citations

THE STRUCTURE OF WATER AND HYDROPHOBIC BONDING IN PROTEINS. III. THE THERMODYNAMIC PROPERTIES OF HYDROPHOBIC BONDS IN PROTEINS^1,2

1962 • 967 citations

Three-dimensional Fourier Synthesis of Horse Oxyhaemoglobin at 2.8 Å Resolution: The Atomic Model

1968 • 908 citations

Ferricytochrome c

1971 • 879 citations

The structure and action of proteins

1969 • 741 citations

Theory of helix-coil transitions in biopolymers

1970 • 734 citations

Structure of crystalline α-chymotrypsin

1972 • 675 citations

Tertiary Structure of Ribonuclease

1967 • 573 citations

A Partial Determination by X-ray Methods, and its Correlation with Chemical Data

1961 • 486 citations

On the conformation of the hen egg-white lysozyme molecule

1967 • 429 citations

Carboxypeptidase A: A Protein and an Enzyme

1971 • 396 citations

Three-dimensional Structure of Tosyl-elastase

1970 • 299 citations

The Conformational Transitions of Uncharged Poly-L-lysine. α Helix-Random Coil-β Structure^*

1967 • 279 citations

The Helix-Coil Transition in Solutions of Polyglutamic Acid

1964 • 278 citations

A High Resolution Structure of an Inhibitor Complex of the Extracellular Nuclease of Staphylococcus aureus

1971 • 264 citations

Reversible Conformational Changes of Myoglobin and Apomyoglobin

1965 • 255 citations

The Structure of Papain

1971 • 242 citations

Three-dimensional fourier synthesis of calf liver cytochrome b5 at 2.8 Å resolution

1972 • 219 citations

The Silk Fibroins

1958 • 182 citations

Repeating Sequences and Gene Duplication in Proteins

1989 • 181 citations

Logical analysis of the mechanism of protein folding

1973 • 167 citations

Stability of the polyglutamic acid .alpha. helix

1968 • 158 citations

Analysis of the code relating sequence to conformation in proteins: Possible implications for the mechanism of formation of helical regions

1971 • 154 citations

Conformational studies of poly‐<scp>L</scp>‐alanine in water

1968 • 149 citations

Experimental Free Energy and Enthalpy of Formation of the α Helix¹

1966 • 146 citations

Structural and functional role of leucine residues in proteins

1973 • 135 citations

On the Helix-Coil Equilibrium in Polypeptides

1963 • 130 citations

Correlation between the distribution of amino acids and alpha helices

1966 • 121 citations

Conformational Studies on Synthetic Poly-α-amino Acids: Factors Influencing the Stability of the Helical Conformation of Poly-L-glutamic Acid and Copolymers of L-Glutamic Acid and L-Leucine^*

1964 • 112 citations

Statistical analysis of the distribution of amino acid residues among helical and non-helical regions in globular proteins

1969 • 96 citations

Statistical analysis of the correlation among amino acid residues in helical, β-stractural and non-regular regions of globular proteins

1971 • 83 citations

Predictions of structural homologies in cytochrome c proteins

1971 • 81 citations

Potentiometric titrations and the helix–coil transition of poly(<scp>L</scp>‐glutamic acid) and poly‐<scp>L</scp>‐lysine in aqueous salt solutions

1968 • 81 citations

The Effect of Protein Denaturants on the Stability of the α Helix¹

1966 • 79 citations

Analysis of the Code Relating Sequence to Secondary Structure in Proteins

1970 • 78 citations

Cooperative Conformational Transitions of Linear Biopolymers

1970 • 77 citations

Conformational Studies on Poly-L-glutamic Acid and Copolymers of L-Glutamic Acid and L-Phenylalanine^*

1966 • 71 citations

The study of α-chymotrypsin by x-ray diffraction. The Third CIBA Medal Lecture

1969 • 68 citations

Tertiary structure in carboxypeptidase

1972 • 65 citations

Thermodynamic parameters of helix‐coil transition in polypeptide chains I. Poly‐(<scp>L</scp>‐glutamic acid)

1971 • 63 citations

Thermodynamic parameters of helix–coil transition in polypeptide chains. II. Poly‐<scp>L</scp>‐lysine

1971 • 61 citations

The relation between amino acid sequence and protein conformation

1967 • 60 citations

Comparison of helix stabilities of poly-L-lysine, poly-L-ornithine, and poly(L-diaminobutyric acid)

1971 • 57 citations

The Stability of the Helical Conformation of Random L-Leucine-L-Glutamic Acid Copolymers in Aqueous Solution¹

1965 • 55 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. VI. Leucine Parameters from Random Poly(hydroxypropylglutamine-co-L-leucine) and Poly(hydroxybutylglutamine-co-L-leucine)

1972 • 54 citations

Kinetics and thermodynamics of the α helix ⇄ β transconformation of poly(L-lysine) and L-leucine copolymers. Compensation phenomenon

1973 • 52 citations

The influence of nearest‐neighboring amino acid residues on aspects of secondary structure of proteins. Attempts to locate α‐helices and β‐sheets

1973 • 49 citations

Effect of side‐chain hydrophobic bonding on the stability of homopolyamino acid α‐helices: Conformational studies of poly‐<scp>L</scp>‐leucine in water

1970 • 47 citations

The Crystal Structure of Rhombohedral 2 Zinc Insulin

1972 • 45 citations

Conformational studies on copolymers of hydroxypropyl-L-glutamine and L-leucine. Circular dichroism studies

1972 • 45 citations

Conformational studies on copolymers ofL-leusine andL-leucine: Circular dichroism and potentiometric titration studies

1972 • 44 citations

Cooperative transition between two helical conformations in a linear system: Poly‐<scp>L</scp>‐proline I ⇌ II. I. Equilibrium studies

1970 • 40 citations

Helix–coil transition for poly(<scp>L</scp>‐glutamic acid) in water–ethanol solutions

1969 • 36 citations

A Model for the Helix-Coil Transition in Specific-Sequence Copolymers of Amino Acids

1971 • 32 citations

Stability of the helical conformation of random <scp>L</scp>‐alanine–<scp>L</scp>‐lysine copolymers in aqueous solution

1970 • 32 citations

Conformational Transitions of Poly(L-tyrosine) in Mixed Water-Ethanol Solvents

1971 • 29 citations

The Helix Interruption Constant for Poly-L-glutamic Acid from the Pressure Dependence of Optical Rotation

1964 • 28 citations

Directional Information Transfer in Protein Helices

1972 • 24 citations

Potentiometric and Microcalorimetric Determination of the Termodynamic Parameters of the Order-Disorder Transition of Poly(L-histidine) in Aqueous Solution

1972 • 20 citations

Extent and stability of the α‐helix in γ‐benzyl <scp>L</scp>‐glutamate–glycine copolymers

1967 • 10 citations

On the formation of secondary and tertiary structure in apomyoglobin

1972 • 9 citations

Helix-coil transition of poly-.delta.-benzyl-L-.alpha.-aminoadipate and poly-L-.alpha.-aminoadipic acid in solution

1972 • 8 citations