Penetration of the signal sequence of Escherichia coli PhoE protein into phospholipid model membranes leads to lipid-specific changes in signal peptide structure and alterations of lipid organization

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

THE COLORIMETRIC DETERMINATION OF PHOSPHORUS

1925 • 19,115 citations

Two dimensional thin layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots

1970 • 3,260 citations

Signal sequences

1985 • 2,179 citations

Intracellular protein topogenesis

1980 • 1,378 citations

Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components.

1975 • 1,175 citations

A putative signal peptidase recognition site and sequence in eukaryotic and prokaryotic signal peptides

1983 • 1,143 citations

31P nuclear magnetic resonance and the head group structure of phospholipids in membranes

1978 • 872 citations

The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis

1981 • 868 citations

Secretory protein translocation across membranes—the role of the ‘docking protein’

1982 • 648 citations

The enzymatic synthesis of phosphatidylserine and purification by CM-cellulose column chromatography

1977 • 566 citations

Relation between various phospholipase actions on human red cell membranes and the interfacial phospholipid pressure in monolayers

1975 • 548 citations

E. coli mutant pleiotropically defective in the export of secreted proteins

1981 • 512 citations

Purification of a membrane-associated protein complex required for protein translocation across the endoplasmic reticulum.

1980 • 502 citations

PROCESSING MECHANISMS IN THE BIOSYNTHESIS OF PROTEINS*

1980 • 461 citations

The Outer Membrane Proteins of Gram-Negative Bacteria: Biosynthesis, Assembly, and Functions

1978 • 457 citations

Secretion and Membrane Localization of Proteins inEscherichia Coli

1980 • 402 citations

Trans‐membrane Translocation of Proteins

1979 • 364 citations

The preference of cholesterol for phosphatidylcholine in mixed phosphatidylcholine-phosphatidylethanolamine bilayers

1976 • 338 citations

Radiolabeling of proteins by reductive alkylation with [14C]formaldehyde and sodium cyanoborohydride

1978 • 317 citations

The structure of melittin in membranes

1986 • 299 citations

A signal sequence receptor in the endoplasmic reticulum membrane

1987 • 291 citations

Binding of metal ions to monolayers of lecithins, plasmalogen, cardiolipin, and dicetyl phosphate

1965 • 281 citations

Analysis of the distribution of charged residues in the N-terminal region of signal sequences: implications for protein export in prokaryotic and eukaryotic cells.

1984 • 230 citations

A defined mutation in the protein export gene within the spc ribosomal protein operon of Escherichia coli: isolation and characterization of a new temperature-sensitive secY mutant.

1984 • 216 citations

The specific interaction of myelin basic protein with lipids at the air-water interface

1973 • 204 citations

Exchange and interactions between lipid layers at the surface of a liposome solution

1979 • 165 citations

Penetration of phospholipid monolayers by cardiotoxins

1981 • 153 citations

In Vivo Function and Membrane Binding Properties Are Correlated for Escherichia coli lamB Signal Peptides

1985 • 130 citations

M13 procoat inserts into liposomes in the absence of other membrane proteins.

1985 • 121 citations

Optimal posttranslational translocation of the precursor of PhoE protein across Escherichia coli membrane vesicles requires both ATP and the protonmotive force

1987 • 120 citations

Exploring the conformational roles of signal sequences: synthesis and conformational analysis of .lambda. receptor protein wild-type and mutant signal peptides

1984 • 117 citations

Conformational studies of the synthetic precursor-specific region of preproparathyroid hormone.

1980 • 109 citations

The interaction of spectrin-actin and synthetic phospholipids. II. The interaction with phosphatidylserine

1979 • 102 citations

Protein export in Escherichia coli requires a soluble activity.

1984 • 100 citations

Signal peptide amino acid sequences in Escherichia coli contain information related to final protein localization. A multivariate data analysis.

1987 • 99 citations

On the translocation of proteins across membranes.

1987 • 95 citations

Incorporation of a synthetic mitochondrial signal peptide into charged and uncharged phospholipid monolayers

1986 • 90 citations

Penetration of a cardiotoxin into cardiolipin model membranes and its implications on lipid organization

1985 • 90 citations

Studies on the lipid dependency and mechanism of the translocation of the mitochondrial precursor protein apocytochrome c across model membranes.

1986 • 88 citations

31P nuclear magnetic resonance and freeze-fracture electron microscopy studies on Escherichia coli. I. Cytoplasmic membrane and total phospholipids

1980 • 87 citations

On the possible participation of acid phospholipids in the translocation of secreted proteins through the bacterial cytoplasmic membrane

1982 • 79 citations

Physicochemical studies on the interaction of pancreatic phospholipase A2 with a micellar substrate analog

1981 • 76 citations

The ATP requiring step in assembly of M13 procoat protein into microsomes is related to preservation of transport competence of the precursor protein.

1987 • 73 citations

Characterization of the interfacial behavior and structure of the signal sequence of Escherichia coli outer membrane pore protein PhoE.

1988 • 72 citations

Monolayer characteristics and thermal behavior of natural and synthetic phosphatidylserines

1987 • 71 citations

Lipid specific penetration of melittin into phospholipid model membranes

1987 • 68 citations

Melittin induces HII phase formation in cardiolipin model membranes

1987 • 67 citations

Investigations on the insertion of the mitochondrial precursor protein apocytochrome c into model membranes

1985 • 66 citations

Reconstitution of rapid and asymmetric assembly of M13 procoat protein into liposomes which have bacterial leader peptidase.

1983 • 65 citations

2H-nuclear magnetic resonance investigations on phospholipid acyl chain order and dynamics in the gramicidin-induced hexagonal HII phase

1987 • 62 citations

Are interactions with phospholipids responsible for pharmacological activities of cardiotoxins?

1983 • 60 citations

Physical and conformational properties of a synthetic leader peptide from M13 coat protein

1984 • 49 citations

Isolation and purification of cardiolipin from beef heart.

1985 • 46 citations

Interactions of mitochondrial precursor protein apocytochrome c with phosphatidylserine in model membranes. A monolayer study

1987 • 33 citations

The leader region of pre-maltose binding protein binds amphiphiles. A model for self-assembly in protein export.

1985 • 28 citations

Influence of membrane-lipid composition on translocation of nascent proteins in heated Escherichia coli

1987 • 23 citations

Circular dichroism studies on synthetic signal peptides

1985 • 21 citations

Interaction of synthetic signal sequence fragments with model membranes

1984 • 16 citations

Interaction of Secretory Protein Precursors with Phospholipids in Liposomes

1984 • 7 citations