TIMP-3 Binds to Sulfated Glycosaminoglycans of the Extracellular Matrix

Matrix Metalloproteinases

1999 • 3,774 citations

MATRIX PROTEOGLYCANS: From Molecular Design to Cellular Function

1998 • 1,623 citations

Tissue inhibitors of metalloproteinases: structure, regulation and biological functions.

1997 • 1,510 citations

Regulation of Intestinal α-Defensin Activation by the Metalloproteinase Matrilysin in Innate Host Defense

1999 • 1,069 citations

Matrix metalloproteinases: structures, evolution, and diversification

1998 • 759 citations

Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1

1997 • 610 citations

TNF‐α converting enzyme (TACE) is inhibited by TIMP‐3

1998 • 604 citations

Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis.

1998 • 468 citations

Shedding of Syndecan-1 and -4 Ectodomains Is Regulated by Multiple Signaling Pathways and Mediated by a Timp-3–Sensitive Metalloproteinase

2000 • 409 citations

The N-terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitory activity

1991 • 324 citations

The Gene Structure of Tissue Inhibitor of Metalloproteinases (TIMP)-3 and Its Inhibitory Activities Define the Distinct TIMP Gene Family

1995 • 295 citations

Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3

1999 • 285 citations

A new inhibitor of metalloproteinases from chicken: ChIMP-3. A third member of the TIMP family.

1992 • 274 citations

Adenovirus-mediated gene delivery of tissue inhibitor of metalloproteinases-3 inhibits invasion and induces apoptosis in melanoma cells.

1998 • 268 citations

Heparan Sulfate Proteoglycans as Extracellular Docking Molecules for Matrilysin (Matrix Metalloproteinase 7)

2000 • 234 citations

TIMP-3 INDUCES CELL DEATH BY STABILIZING TNF-α RECEPTORS ON THE SURFACE OF HUMAN COLON CARCINOMA CELLS

1997 • 190 citations

Imbalance between interstitial collagenase and tissue inhibitor of metalloproteinases 1 in synoviocytes and fibroblasts upon direct contact with stimulated T lymphocytes: Involvement of membrane-associated cytokines

1998 • 152 citations

A review of tissue inhibitor of metalloproteinases-3 (TIMP-3) and experimental analysis of its effect on primary tumor growth

1996 • 149 citations

Role of the 21-kDa protein TIMP-3 in oncogenic transformation of cultured chicken embryo fibroblasts.

1992 • 137 citations

Gene encoding a novel murine tissue inhibitor of metalloproteinases (TIMP), TIMP‐3, is expressed in developing mouse epithelia, cartilage, and muscle, and is located on mouse chromosome 10

1994 • 135 citations

Localization of the Functional Domains of Human Tissue Inhibitor of Metalloproteinases-3 and the Effects of a Sorsby's Fundus Dystrophy Mutation

1998 • 128 citations

Tissue Inhibitor of Metalloproteinases-3 Inhibits Shedding of L-selectin from Leukocytes

1999 • 126 citations

Pentosan Polysulfate Decreases Proliferation and Net Extracellular Matrix Production in Mouse Mesangial Cells

1999 • 124 citations

Human Tissue Inhibitor of Metalloproteinases 3 Interacts with Both the N- and C-terminal Domains of Gelatinases A and B

1999 • 116 citations

Accumulation of tissue inhibitor of metalloproteinases-3 in human eyes with Sorsby's fundus dystrophy or retinitis pigmentosa

1998 • 115 citations

Solution structure of the active domain of tissue inhibitor of metalloproteinases-2. A new member of the OB fold protein family

1994 • 105 citations

Computational Sequence Analysis of the Tissue Inhibitor of Metalloproteinase Family

1997 • 98 citations

Extraction of collagenase from the involuting rat uterus

1976 • 96 citations

Three-dimensional structure of human tissue inhibitor of metalloproteinases-2 at 2.1 Å resolution

1998 • 96 citations

Human myeloma cells shed the interleukin‐6 receptor: inhibition by tissue inhibitor of metalloproteinase‐3 and a hydroxamate‐based metalloproteinase inhibitor

1998 • 94 citations

Transformation-sensitive protein associated with the cell substratum of chicken embryo fibroblasts

1983 • 50 citations

Gene Trapping Identifies Inhibitors of Oncogenic Transformation

1998 • 44 citations

Chemically and Conformationally Authentic Active Domain of Human Tissue Inhibitor of Metalloproteinases‐2 Refolded from Bacterial Inclusion Bodies

1996 • 44 citations

Characterization of a transformation-sensitive protein in the extracellular matrix of chicken embryo fibroblasts.

1984 • 41 citations

Multiple functions of tissue inhibitors of metalloproteinases (TIMPs): new aspects in hematopoiesis

1999 • 29 citations

Homogeneous Enzyme-Based Binding Assay for Studying Glycosaminoglycan Interactions with Macromolecules and Peptides

1996 • 13 citations