Three-dimensional structure of human tissue inhibitor of metalloproteinases-2 at 2.1 Å resolution

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

Refinement of Macromolecular Structures by the Maximum-Likelihood Method

1997 • 14,729 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

AMoRe: an automated package for molecular replacement

1994 • 4,990 citations

Raster3D Version 2.0. A program for photorealistic molecular graphics

1994 • 2,515 citations

Crystallographic R Factor Refinement by Molecular Dynamics

1987 • 1,982 citations

Tissue inhibitors of metalloproteinases: structure, regulation and biological functions.

1997 • 1,510 citations

The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.

1990 • 1,423 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

Proteolytic remodeling of extracellular matrix

1995 • 1,086 citations

OB(oligonucleotide/oligosaccharide binding)-fold: common structural and functional solution for non-homologous sequences.

1993 • 917 citations

A fast algorithm for rendering space-filling molecule pictures

1988 • 616 citations

Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1

1997 • 610 citations

Extracellular matrix 6: Role of matrix metalloproteinases in tumor invasion and metastasis

1993 • 606 citations

The TIMP2 Membrane Type 1 Metalloproteinase “Receptor” Regulates the Concentration and Efficient Activation of Progelatinase A

1998 • 578 citations

Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA

1997 • 557 citations

Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2 (TIMP-2)

1994 • 456 citations

Metalloproteinases and cancer invasion.

1990 • 399 citations

Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor

1998 • 360 citations

Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization.

1992 • 331 citations

The N-terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitory activity

1991 • 324 citations

Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) Binds to the Catalytic Domain of the Cell Surface Receptor, Membrane Type 1-Matrix Metalloproteinase 1 (MT1-MMP)

1998 • 285 citations

Messenger RNA for two type IV collagenases is located in stromal cells in human colon cancer.

1993 • 283 citations

Kinetic Analysis of the Binding of Human Matrix Metalloproteinase-2 and -9 to Tissue Inhibitor of Metalloproteinase (TIMP)-1 and TIMP-2

1997 • 279 citations

The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: A kinetic analysis of the inhibition of gelatinase A

1993 • 237 citations

Tissue inhibitor of metalloproteinase‐2 (TIMP‐2) has erythroid‐potentiating activity

1992 • 200 citations

Molecular cloning of murine 72-kDa type IV collagenase and its expression during mouse development.

1992 • 189 citations

Specific, High Affinity Binding of Tissue Inhibitor of Metalloproteinases-4 (TIMP-4) to the COOH-terminal Hemopexin-like Domain of Human Gelatinase A

1997 • 160 citations

Mapping the Binding Site for Matrix Metalloproteinase on the N-Terminal Domain of the Tissue Inhibitor of Metalloproteinases-2 by NMR Chemical Shift Perturbation

1997 • 113 citations

Solution structure of the active domain of tissue inhibitor of metalloproteinases-2. A new member of the OB fold protein family

1994 • 105 citations

The gelatin-binding site of human 72 kDa type IV collagenase (gelatinase A)

1994 • 88 citations

Purification and characterization of a two-chain form of tissue inhibitor of metalloproteinases (TIMP) type 2 and a low molecular weight TIMP-like protein

1993 • 54 citations

Tissue Inhibitors of Metalloproteinases

2011 • 27 citations