Contrasting CD25hiCD4+T Cells/FOXP3 Patterns in Chronic Rejection and Operational Drug-Free Tolerance

Control of Regulatory T Cell Development by the Transcription Factor Foxp3

2003 • 7,902 citations

CD4+CD25high Regulatory Cells in Human Peripheral Blood

2001 • 1,882 citations

Loss of Functional Suppression by CD4+CD25+ Regulatory T Cells in Patients with Multiple Sclerosis

2004 • 1,835 citations

Improved Graft Survival after Renal Transplantation in the United States, 1988 to 1996

2000 • 1,803 citations

Prevalence of Regulatory T Cells Is Increased in Peripheral Blood and Tumor Microenvironment of Patients with Pancreas or Breast Adenocarcinoma

2002 • 1,454 citations

Phenotypic and Functional Separation of Memory and Effector Human CD8+ T Cells

1997 • 1,391 citations

Regulatory T cells in transplantation tolerance

2003 • 1,323 citations

Regulatory T Cells in Autoimmmunity

2000 • 1,267 citations

Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

2003 • 1,252 citations

Homeostatic maintenance of natural Foxp3+ CD25+ CD4+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

2005 • 1,189 citations

Ex Vivo Isolation and Characterization of Cd4+Cd25+ T Cells with Regulatory Properties from Human Blood

2001 • 1,168 citations

Cyclosporine induces cancer progression by a cell-autonomous mechanism

1999 • 1,119 citations

Human Cd25+Cd4+ T Regulatory Cells Suppress Naive and Memory T Cell Proliferation and Can Be Expanded in Vitro without Loss of Function

2001 • 1,008 citations

Unique Chemotactic Response Profile and Specific Expression of Chemokine Receptors Ccr4 and Ccr8 by Cd4+Cd25+ Regulatory T Cells

2001 • 888 citations

Effect of long-term immunosuppression in kidney-graft recipients on cancer incidence: randomised comparison of two cyclosporin regimens

1998 • 724 citations

Human CD4+CD25+ thymocytes and peripheral T cells have immune suppressive activityin vitro

2001 • 498 citations

Expression of the integrin α_Eβ₇identifies unique subsets of CD25⁺as well as CD25⁻regulatory T cells

2002 • 476 citations

Isolation and functional characterization of regulatory CD25^brightCD4⁺ T cells from the target organ of patients with rheumatoid arthritis

2003 • 452 citations

Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression

2000 • 448 citations

Human CD25+CD4+ T Suppressor Cell Clones Produce Transforming Growth Factor β, but not Interleukin 10, and Are Distinct from Type 1 T Regulatory Cells

2002 • 440 citations

Functional defect of regulatory CD4+CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis

2004 • 420 citations

Human immunodeficiency virus–driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients

2004 • 387 citations

Role of NKG2D signaling in the cytotoxicity of activated and expanded CD8+ T cells

2003 • 370 citations

Defective Suppressor Function of Human CD4+ CD25+ Regulatory T Cells in Autoimmune Polyglandular Syndrome Type II

2004 • 359 citations

Association of Foxp3 regulatory gene expression with graft-versus-host disease

2004 • 313 citations

Frequency and Clinical Implications of Development of Donor-Specific and Non–Donor-Specific HLA Antibodies after Kidney Transplantation

2005 • 290 citations

Analyses of Peripheral Blood Mononuclear Cells in Operational Tolerance After Pediatric Living Donor Liver Transplantation

2004 • 263 citations

Increased expression of NK cell markers on T lymphocytes in aging and chronic activation of the immune system reflects the accumulation of effector/senescent T cells

2001 • 257 citations

Favorably Tipping the Balance between Cytopathic and Regulatory T Cells to Create Transplantation Tolerance

2003 • 255 citations

Regulating the Immune Response to Transplants

2001 • 242 citations

Regulatory CD25+ T Cells in Human Kidney Transplant Recipients

2003 • 232 citations

CD4+CD25+ regulatory T-cell deficiency in patients with hepatitis C-mixed cryoglobulinemia vasculitis

2003 • 221 citations

Chronic graft-versus-host disease is associated with increased numbers of peripheral blood CD4+CD25high regulatory T cells

2003 • 214 citations

T Cells Primed byLeishmania majorInfection Cross-React with Alloantigens and Alter the Course of Allograft Rejection

2002 • 158 citations

Prednisone-induced leukocytosis

1981 • 133 citations

CLINICAL TRANSPLANTATION TOLERANCE TWELVE YEARS AFTER PROSPECTIVE WITHDRAWAL OF IMMUNOSUPPRESSIVE DRUGS: STUDIES OF CHIMERISM AND ANTI-DONOR REACTIVITY1

2000 • 128 citations

Regulatory CD4+CD25+ T cells in the peripheral blood of lung transplant recipients: correlation with transplant outcome

2004 • 126 citations

Dendritic Cell Subset Ratio in Tolerant, Weaning and Non-Tolerant Liver Recipients Is Not Affected by Extent of Immunosuppression

2005 • 116 citations

Role for Thymic and Splenic Regulatory CD4+ T Cells Induced by Donor Dendritic Cells in Allograft Tolerance by LF15-0195 Treatment

2002 • 103 citations

Phenotypically and Functionally Distinct CD8+ Lymphocyte Populations in Long-Term Drug-Free Tolerance and Chronic Rejection in Human Kidney Graft Recipients

2005 • 103 citations

Operationally Tolerant and Minimally Immunosuppressed Kidney Recipients Display Strongly Altered Blood T-Cell Clonal Regulation

2005 • 96 citations

Regulatory T Cells in the Control of Transplantation Tolerance and Autoimmunity

2003 • 90 citations

Detection of T suppressor cells in patients with organ allografts

2001 • 81 citations

HYPERLIPIDEMIA AND CARDIOVASCULAR DISEASE AFTER ORGAN TRANSPLANTATION

2001 • 55 citations

Tailoring of immunosuppression in renal and liver allograft recipients displaying donor specific T-suppressor cells

2002 • 44 citations

N-TERMINAL FRAGMENTS OF THE PROATRIAL NATRIURETIC PEPTIDE IN PLASMA AND URINE OF KIDNEY GRAFT RECIPIENTS

2001 • 32 citations

The concept of “partial” clinical tolerance

2004 • 29 citations

FK506 and Cyclosporin A Each Inhibit Antigen-Specific Signaling in the T Cell Line 171 in the Absence of a Calcium Signal

1994 • 23 citations

Induction therapy including antithymocyte globulin induces marked alterations in T lymphocyte subpopulations after liver transplantation: results of a long-term study

2002 • 20 citations

Kidney Transplant Patients with Long-Term Graft Survival Have Altered Expression of Molecules Associated with T-Cell Activation

2004 • 20 citations

CYTOTOXIC PATHWAYS IN THE SKIN ALLOGRAFT REJECTION BY CD4+ T CELLS

1999 • 16 citations