Functional defect of regulatory CD4+CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis

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The Role of Tumoral FOXP3 on Cell Proliferation, Migration, and Invasion in Gastric Cancer

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

2001 • 3,260 citations

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CD4+CD25+ suppressor T cells: more questions than answers

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Toll Pathway-Dependent Blockade of CD4 ⁺ CD25 ⁺ T Cell-Mediated Suppression by Dendritic Cells

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CD4+CD25high Regulatory Cells in Human Peripheral Blood

2001 • 1,882 citations

Loss of Functional Suppression by CD4+CD25+ Regulatory T Cells in Patients with Multiple Sclerosis

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

2001 • 1,831 citations

Cell Contact–Dependent Immunosuppression by Cd4+Cd25+Regulatory T Cells Is Mediated by Cell Surface–Bound Transforming Growth Factor β

2001 • 1,609 citations

Identification and Functional Characterization of Human Cd4+Cd25+ T Cells with Regulatory Properties Isolated from Peripheral Blood

2001 • 1,293 citations

Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

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Ex Vivo Isolation and Characterization of Cd4+Cd25+ T Cells with Regulatory Properties from Human Blood

2001 • 1,168 citations

Human Cd25+Cd4+ T Regulatory Cells Suppress Naive and Memory T Cell Proliferation and Can Be Expanded in Vitro without Loss of Function

2001 • 1,008 citations

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JM2, encoding a fork head–related protein, is mutated in X-linked autoimmunity–allergic disregulation syndrome

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Human CD4+CD25+ thymocytes and peripheral T cells have immune suppressive activityin vitro

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1994 • 200 citations

Myasthenic thymus and thymoma are selectively enriched in acetylcholine receptor–reactive T cells

1990 • 153 citations

A functional polymorphism in the promoter/enhancer region of the FOXP3/Scurfin gene associated with type 1 diabetes

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Expression of acetylcholine receptor genes in human thymic epithelial cells: implications for myasthenia gravis.

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The Thymus Contains a High Frequency of Cells that Prevent Autoimmune Diabetes on Transfer into Prediabetic Recipients

1996 • 128 citations

Circulating CD4⁺CD25⁺T Regulatory Cells Are Not Altered in Multiple Sclerosis and Unaffected by Disease-Modulating Drugs

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Thymic B cells from myasthenia gravis patients are activated B cells. Phenotypic and functional analysis.

1990 • 90 citations

Anti‐AChR antibodies, thymic histology, and T cell subsets in myasthenia gravis

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Autoimmune T lymphocytes in myasthenia gravis. Determination of target epitopes using T lines and recombinant products of the mouse nicotinic acetylcholine receptor gene.

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Increased Fas antigen on T cells in multiple sclerosis

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Thymocyte Fas Expression Is Dysregulated in Myasthenia Gravis Patients With Anti-Acetylcholine Receptor Antibody

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An acetylcholine receptor alpha subunit promoter confers intrathymic expression in transgenic mice. Implications for tolerance of a transgenic self-antigen and for autoreactivity in myasthenia gravis.

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Myasthenia gravis: effect of thymectomy in 425 patients A 15-year experience

1990 • 41 citations

Interleukin-6 overproduction by cultured thymic epithelial cells from patients with myasthenia gravis is potentially involved in thymic hyperplasia.

1993 • 40 citations

Acetylcholine receptor subunit gene expression in thymic tissue

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Evidence of enhanced recombinant interleukin-2 sensitivity in thymic lymphocytes from patients with myasthenia gravis: possible role in autoimmune pathogenesis

1989 • 32 citations

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