Prognostic Impact of Platelet-Derived Growth Factors in Non-small Cell Lung Cancer Tumor and Stromal Cells

Cancer Statistics, 2007

2007 • 7,372 citations

Angiogenesis as a therapeutic target

2005 • 2,543 citations

Paradoxical roles of the immune system during cancer development

2006 • 2,213 citations

Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice

1997 • 2,136 citations

Histological Typing of Lung and Pleural Tumours

1999 • 1,538 citations

Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

2003 • 1,236 citations

Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

2003 • 1,172 citations

Gain-of-function mutations of platelet-derived growth factor receptor α gene in gastrointestinal stromal tumors

2003 • 665 citations

Preoperative Chemotherapy Followed by Surgery Compared With Primary Surgery in Resectable Stage I (Except T1N0), II, and IIIa Non–Small-Cell Lung Cancer

2002 • 568 citations

A Multitargeted, Metronomic, and Maximum-Tolerated Dose “Chemo-Switch” Regimen is Antiangiogenic, Producing Objective Responses and Survival Benefit in a Mouse Model of Cancer

2004 • 479 citations

Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors.

2002 • 432 citations

Endothelium-specific platelet-derived growth factor-B ablation mimics diabetic retinopathy

2002 • 378 citations

Biology of Platelet-Derived Growth Factor and Its Involvement in Disease

2006 • 324 citations

VEGF-null cells require PDGFR α signaling-mediated stromal fibroblast recruitment for tumorigenesis

2004 • 287 citations

New Members of the Platelet-Derived Growth Factor Family of Mitogens

2002 • 221 citations

PDGF Receptors as Targets in Tumor Treatment

2007 • 214 citations

Role of Adjuvant Chemotherapy in Patients With Resected Non–Small-Cell Lung Cancer: Reappraisal With a Meta-Analysis of Randomized Controlled Trials

2004 • 202 citations

Novel PDGF family members: PDGF-C and PDGF-D

2003 • 184 citations

A novel physiological function for platelet‐derived growth factor‐BB in rat dermis.

1996 • 135 citations

Tumor-Driven Paracrine Platelet-Derived Growth Factor Receptor α Signaling Is a Key Determinant of Stromal Cell Recruitment in a Model of Human Lung Carcinoma

2006 • 119 citations

Sorafenib and Sunitinib in the Treatment of Advanced Non-Small Cell Lung Cancer

2007 • 114 citations

Inverse Prognostic Impact of Angiogenic Marker Expression in Tumor Cells versus Stromal Cells in Non–Small Cell Lung Cancer

2007 • 105 citations

Platelet-Derived Growth Factor-AA Is an Essential and Autocrine Regulator of Vascular Endothelial Growth Factor Expression in Non–Small Cell Lung Carcinomas

2005 • 101 citations

Expression in lung carcinomas of platelet-derived growth factor and its receptors.

1997 • 98 citations

Addition of platinum compounds to a new agent in patients with advanced non-small-cell lung cancer: a literature based meta-analysis of randomised trials

2004 • 98 citations

Expression of receptor tyrosine kinases and apoptotic molecules in rhabdomyosarcoma

2007 • 71 citations

Platelet Derived Growth Factor (PDGF) autocrine components in human tumor cell lines

1990 • 69 citations

Treatment with imatinib improves drug delivery and efficacy in NSCLC xenografts

2007 • 64 citations

Antagonism of Platelet-Derived Growth Factor Receptor in Non–Small Cell Lung Cancer: Rationale and Investigations

2007 • 27 citations

Prognostic value of platelet derived growth factor alpha receptor expression in grade 2 astrocytomas and oligoastrocytomas

2002 • 20 citations

Treatment of Locally Advanced Non-Small Cell Lung Cancer: What We Have and Have Not Learned Over the Past Decade

2005 • 10 citations