Effects of specific anti‐B and/or anti‐plasma cell immunotherapy on antibody production in baboons: depletion of CD20‐ and CD22‐positive B cells does not result in significantly decreased production of anti‐αGal antibody

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii

2007 • 11,720 citations

Humoral Immunity Due to Long-Lived Plasma Cells

1998 • 1,223 citations

Characterization of a human B lymphocyte-specific antigen.

1980 • 1,098 citations

Interaction of the natural anti-Gal antibody with α-galactosyl epitopes: a major obstacle for xenotransplantation in humans

1993 • 645 citations

Identification of carbohydrate structures that bind human antiporcine antibodies: implications for discordant xenografting in humans.

1992 • 626 citations

Evolutionary relationship between the natural anti-Gal antibody and the Gal alpha 1----3Gal epitope in primates.

1987 • 544 citations

Radiation-induced apoptosis: Relevance to radiotherapy

1995 • 504 citations

IMMUNOPATHOLOGY OF HYPERACUTE XENOGRAFT REJECTION IN A SWINE-TO-PRIMATE MODEL

1991 • 459 citations

CARBOHYDRATE ANTIGENS OF PIG TISSUES REACTING WITH HUMAN NATURAL ANTIBODIES AS POTENTIAL TARGETS FOR HYPERACUTE VASCULAR REJECTION IN PIG-TO-MAN ORGAN XENOTRANSPLANTATION1

1993 • 410 citations

Human CD38: a glycoprotein in search of a function

1994 • 360 citations

The pig as a potential xenograft donor

1994 • 331 citations

Redesigning Nature's Poisons to Create Anti-Tumor Reagents

1987 • 329 citations

Recombinant Toxins for Cancer Treatment

1991 • 308 citations

Phase I immunotoxin trial in patients with B-cell lymphoma.

1991 • 289 citations

Barriers to xenotransplantation

1995 • 271 citations

LIFE-SUPPORTING PIG-TO-PRIMATE RENAL XENOTRANSPLANTATION USING GENETICALLY MODIFIED DONORS

1998 • 265 citations

Monoclonal antibody-based therapies of leukemia and lymphoma

1992 • 213 citations

Generation of Plasma Cells From Peripheral Blood Memory B Cells: Synergistic Effect of Interleukin-10 and CD27/CD70 Interaction

1998 • 204 citations

ORTHOTOPIC HEART TRANSPLANTATION IN A TRANSGENIC PIG-TO-PRIMATE MODEL1

1998 • 203 citations

HIGH-DOSE PORCINE HEMATOPOIETIC CELL TRANSPLANTATION COMBINED WITH CD40 LIGAND BLOCKADE IN BABOONS PREVENTS AN INDUCED ANTI-PIG HUMORAL RESPONSE

2000 • 198 citations

REMOVAL OF ANTI-PORCINE NATURAL ANTIBODIES FROM HUMAN AND NONHUMAN PRIMATE PLASMA IN VITRO AND IN VIVO BY A Gal??1-3Gal??1-4??Glc-X IMMUNOAFFINITY COLUMN

1998 • 197 citations

Human B cell development. I. Phenotypic differences of B lymphocytes in the bone marrow and peripheral lymphoid tissue.

1985 • 188 citations

PORCINE KIDNEY AND HEART TRANSPLANTATION IN BABOONS UNDERGOING A TOLERANCE INDUCTION REGIMEN AND ANTIBODY ADSORPTION1

1999 • 171 citations

Continuous infusion of the anti-CD22 immunotoxin IgG-RFB4-SMPT-dgA in patients with B-cell lymphoma: a phase I study

1995 • 165 citations

Improved antitumor effects of immunotoxins prepared with deglycosylated ricin A-chain and hindered disulfide linkages.

1988 • 155 citations

IN VIVO IMMUNOADSORPTION OF ANTIPIG ANTIBODIES IN BABOONS USING A SPECIFIC GAL??1-3GAL COLUMN

1996 • 143 citations

Depletion of anti‐Galα1–3Gal antibody in baboons by specific α‐Gal immunoaffinity columns

1998 • 115 citations

The antitumor activity of an anti-CD22 immunotoxin in SCID mice with disseminated Daudi lymphoma is enhanced by either an anti-CD19 antibody or an anti-CD19 immunotoxin

1992 • 98 citations

The problem of anti‐pig antibodies in pig‐to‐primate xenografting: current and novel methods of depletion and/or suppression of production of anti‐pig antibodies

1999 • 84 citations

ANTI-Gal??1-3Gal ANTIBODY RESPONSE TO PORCINE BONE MARROW IN UNMODIFIED BABOONS AND BABOONS CONDITIONED FOR TOLERANCE INDUCTION1

1998 • 84 citations

Xenotransplantation of pig kidneys to nonhuman primates: I. Development of the model

1995 • 79 citations

The antitumor activity of an anti-CD22 immunotoxin in SCID mice with disseminated Daudi lymphoma is enhanced by either an anti-CD19 antibody or an anti-CD19 immunotoxin

1992 • 72 citations

Rituximab (anti-CD20 monoclonal antibody) for the treatment of patients with clonal lymphoproliferative disorders after orthotopic liver transplantation: a report of three cases

2000 • 64 citations

Pharmacologic immunosuppressive therapy and extracorporeal immunoadsorption in the suppression of anti‐αGal antibody in the baboon

1998 • 63 citations

Complete Sustained Response of a Refractory, Post-Transplantation, Large B-Cell Lymphoma to an Anti-CD22 Immunotoxin

1997 • 57 citations

A histopathologic grading system of hyperacute (humoral, antibody-mediated) cardiac xenograft and allograft rejection.

1996 • 55 citations

Systemic therapy with 3BIT, a triple combination cocktail of anti-CD19, -CD22, and -CD38-saporin immunotoxins, is curative of human B-cell lymphoma in severe combined immunodeficient mice.

1997 • 49 citations

Plasma perfusion by apheresis through a Gal immunoaffinity column successfully depletes anti‐Gal antibody: experience with 320 aphereses in baboons

2000 • 49 citations

Treatment of plasma cell dyscrasias by antibody-mediated immunotherapy.

1999 • 48 citations

Xeno

2000 • 47 citations

The radiation resistance of long-lived lymphocytes and plasma cells in mouse and rat lymph nodes

1967 • 44 citations

Eradication of minimal disease in severe combined immunodeficient mice with disseminated Daudi lymphoma using chemotherapy and an immunotoxin cocktail

1994 • 39 citations

The Radiation Resistance of Long-Lived Lymphocytes and Plasma Cells in Mouse and Rat Lymph Nodes

1967 • 36 citations

Xenogeneic bone marrow transplantation: II. Porcine‐specific growth factors enhance porcine bone marrow engraftment in an in vitro primate microenvironment

1997 • 33 citations

Xenotransplantation

1991 • 31 citations

Eradication of minimal disease in severe combined immunodeficient mice with disseminated Daudi lymphoma using chemotherapy and an immunotoxin cocktail

1994 • 29 citations

Splenectomy improves survival of HDAF transgenic pig kidneys in primates

1999 • 24 citations

Anti-αgalactosyl (Anti-Gal) Antibody Damage Beyond Hyperacute Rejection

1997 • 15 citations

Human Blood Dendritic Cell-Like B Cells Isolated by the 5G9 Monoclonal Antibody Reactive with a Novel 220-kDa Antigen

1999 • 15 citations

Prolongation of survival of guinea pig heart grafts in cobra venom factor-treated rats by splenectomy. No additional effect of cyclosporine.

1995 • 12 citations