Pharmacologic immunosuppressive therapy and extracorporeal immunoadsorption in the suppression of anti‐αGal antibody in the baboon

Identification of carbohydrate structures that bind human antiporcine antibodies: implications for discordant xenografting in humans.

1992 • 626 citations

Anti-pig IgM antibodies in human serum react predominantly with Gal(alpha 1-3)Gal epitopes.

1993 • 611 citations

Mixed Allogeneic Chimerism And Renal Allograft Tolerance In Cynomolgus Monkeys

1995 • 552 citations

Treatment for multiple myeloma. Combination chemotherapy with different melphalan dose regimens

1969 • 512 citations

CARBOHYDRATE ANTIGENS OF PIG TISSUES REACTING WITH HUMAN NATURAL ANTIBODIES AS POTENTIAL TARGETS FOR HYPERACUTE VASCULAR REJECTION IN PIG-TO-MAN ORGAN XENOTRANSPLANTATION1

1993 • 410 citations

Treatment for Multiple Myeloma

1969 • 377 citations

Identification of α-galactosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: relevance to discordant xenografting in man

1993 • 363 citations

Barriers to xenotransplantation

1995 • 271 citations

REMOVAL OF ANTI-PORCINE NATURAL ANTIBODIES FROM HUMAN AND NONHUMAN PRIMATE PLASMA IN VITRO AND IN VIVO BY A Gal??1-3Gal??1-4??Glc-X IMMUNOAFFINITY COLUMN

1998 • 197 citations

DELAYED XENOGRAFT REJECTION OF PIG-TO-BABBON CARDIAC TRANSPLANTS AFTER COBRA VENOM FACTOR THERAPY

1997 • 162 citations

Immunoadsorption for Removal of a and B Blood-Group Antibodies

1981 • 148 citations

Anti‐Gal activity In diabetic patients transplanted with fetal porcine Islet cell clusters

1995 • 146 citations

EVIDENCE THAT INTRAVENOUSLY ADMINISTERED α-GALACTOSYL CARBOHYDRATES REDUCE BABOON SERUM CYTOTOXICITY TO PIG KIDNEY CELLS (PK15) AND TRANSPLANTED PIG HEARTS

1994 • 130 citations

PORCINE AND BOVINE CARTILAGE TRANSPLANTS IN CYNOMOLGUS MONKEY

1997 • 120 citations

Depletion of anti‐Galα1–3Gal antibody in baboons by specific α‐Gal immunoaffinity columns

1998 • 115 citations

Accommodation: a working paradigm for progressing toward clinical discordant xenografting.

1991 • 112 citations

PROTECTION OF PIG KIDNEY (PK15) CELLS FROM THE CYTOTOXIC EFFECT OF ANTI-PIG ANTIBODIES BY α-GALACTOSYL OLIGOSACCHARIDES1

1994 • 111 citations

SPECIFIC INTRAVENOUS CARBOHYDRATE THERAPY A NEW CONCEPT IN INHIBITING ANTIBODY-MEDIATED REJECTION—EXPERIENCE WITH ABO-INCOMPATIBLE CARDIAC ALLOGRAFTING IN THE BABOON

1993 • 103 citations

Splenectomy As a Prerequisite for Successful Human Abo-incompatible Renal-transplantation

1985 • 91 citations

Experiences with known ABO-mismatched renal transplants.

1987 • 85 citations

ANTI-Gal??1-3Gal ANTIBODY RESPONSE TO PORCINE BONE MARROW IN UNMODIFIED BABOONS AND BABOONS CONDITIONED FOR TOLERANCE INDUCTION1

1998 • 84 citations

Xenotransplantation of pig kidneys to nonhuman primates: I. Development of the model

1995 • 79 citations

Melphalan in Multiple Myeloma

1967 • 79 citations

Tolerance across discordant xenogeneic barriers

1995 • 79 citations

Pig to monkey bone marrow and kidney xenotransplantation

1997 • 77 citations

EVIDENCE THAT 15-DEOXYSPERGUALIN INHIBITS NATURAL ANTIBODY PRODUCTION BUT FAILS TO PREVENT HYPERACUTE REJECTION IN A DISCORDANT XENOGRAFT MODEL

1992 • 55 citations

A histopathologic grading system of hyperacute (humoral, antibody-mediated) cardiac xenograft and allograft rejection.

1996 • 55 citations

Chemical action and pharmacology of methotrexate, azathioprine and cyclophosphamide in man

1973 • 52 citations

Tolerance and xenograft survival

1995 • 49 citations

SUPPRESSION OF SYNTHESIS OF NATURAL ANTIBODIES BY MYCOPHENOLATE MOFETIL (RS-61443)

1993 • 46 citations

Handbook of Animal Models in Transplantation Research

2024 • 44 citations

Hematopoietic cell transplantation for the induction of allo‐ and xenotolerance

1996 • 37 citations

Xenotransplantation from pig to cynomolgus monkey: the potential for overcoming xenograft rejection through induction of chimerism.

1994 • 35 citations

DISCORDANT HEART XENOGRAFTS IN THE RAT

1988 • 32 citations

Sensitivity of baboon lymphocytes to cyclosporin A and FK 506: relative resistance of alloactivated cells to CyA

1994 • 26 citations

A study of tolerance in a concordant xenograft model

1997 • 26 citations

Xenotransplantation from pig to cynomolgus monkey: approach toward tolerance induction.

1993 • 21 citations

Sensitivity of baboon lymphocytes to cyclosporin A and FK 506: relative resistance of alloactivated cells to CyA

1994 • 20 citations

In vitro model for hyperacute rejection of xenogeneic cells.

1994 • 16 citations

Influence of the exercise protocol on hemodynamic, gas exchange, and neurohumoral responses to exercise in heart transplant recipients.

1996 • 13 citations

The effect of a new immunosuppressive drug, brequinar sodium, on concordant hamster-to-rat cardiac xenografts.

1992 • 11 citations

Anti-B cell agents: suppression of natural antibodies and prolongation of survival in discordant xenografts.

1994 • 9 citations

Effect of brequinar sodium on in vivo antibody production.

1993 • 9 citations

Efficacy of leflunomide to reduce xenoantibody titers in vivo: an evaluation of the prolongation of discordant xenograft survival.

1996 • 8 citations

Cyclophosphamide in cardiac transplant recipients with frequent rejection: a six-year retrospective review.

1996 • 8 citations

Successful down-regulation of natural and xenoreactive antibodies in pig-to-baboon xenotransplantation by high-dose cyclophosphamide

1997 • 6 citations

Mechanism of Cellular Xenograft Rejection

1997 • 6 citations

Cyclophosphamide in cardiac transplant recipients with frequent rejection: a six‐year retrospective review

1996 • 4 citations

Pharmacologic Immunosuppressants in Xenotransplantation

1997 • 4 citations

Suppression of immunoglobulin resynthesis after plasmapheresis: efficacy of various immunosuppressive drugs--a study in rats.

1995 • 3 citations