Recruitment of a Nicotinic Acetylcholine Receptor Mutant Lacking Cytoplasmic Tyrosine Residues in Its β Subunit into Agrin-Induced Aggregates

Defective Neuromuscular Synaptogenesis in Agrin-Deficient Mutant Mice

1996 • 915 citations

The Receptor Tyrosine Kinase MuSK Is Required for Neuromuscular Junction Formation In Vivo

1996 • 881 citations

Agrin Acts via a MuSK Receptor Complex

1996 • 653 citations

The Agrin Hypothesis

1990 • 637 citations

Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice

1995 • 530 citations

Synapse formation between dissociated nerve and muscle cells in low density cell cultures

1972 • 456 citations

Receptor tyrosine kinase specific for the skeletal muscle lineage: Expression in embryonic muscle, at the neuromuscular junction, and after injury

1995 • 409 citations

Agrin induces phosphorylation of the nicotinic acetylcholine receptor

1991 • 253 citations

The agrin gene codes for a family of basal lamina proteins that differ in function and distribution

1992 • 252 citations

Rapsyn Is Required for MuSK Signaling and Recruits Synaptic Components to a MuSK-Containing Scaffold

1997 • 243 citations

Agrin released by motor neurons induces the aggregation of acetylcholine receptors at neuromuscular junctions

1992 • 231 citations

Regulation of Ion Channel Distribution at Synapses

1993 • 177 citations

Muscle-specific trk-related receptor with a kringle domain defines a distinct class of receptor tyrosine kinases.

1993 • 163 citations

Agrin-induced specializations contain cytoplasmic, membrane, and extracellular matrix-associated components of the postsynaptic apparatus

1989 • 163 citations

Agrin-induced acetylcholine receptor clustering in mammalian muscle requires tyrosine phosphorylation.

1996 • 151 citations

Location of antigenic determinants of primary sequences of the subunits of nicotinic acetylcholine receptor by peptide mapping

1986 • 146 citations

Laminin-induced Acetylcholine Receptor Clustering: An Alternative Pathway

1997 • 138 citations

Characteristics of monoclonal antibodies to denatured Torpedo and to native calf acetylcholine receptors: Species, subunit and region specificity

1986 • 127 citations

Laminin and α-Dystroglycan Mediate Acetylcholine Receptor Aggregation via a MuSK-Independent Pathway

1998 • 122 citations

Rapsyn Clusters and Activates the Synapse-Specific Receptor Tyrosine Kinase MuSK

1996 • 110 citations

Association of muscle-specific kinase MuSK with the acetylcholine receptor in mammalian muscle

1997 • 110 citations

Staurosporine inhibits agrin-induced acetylcholine receptor phosphorylation and aggregation.

1994 • 104 citations

Regulation of the interaction of nicotinic acetylcholine receptors with the cytoskeleton by agrin-activated protein tyrosine kinase.

1995 • 100 citations

Functional Interaction of Src Family Kinases with the Acetylcholine Receptor in C2 Myotubes

1996 • 94 citations

Kinase domain of the muscle-specific receptor tyrosine kinase (MuSK) is sufficient for phosphorylation but not clustering of acetylcholine receptors: Required role for the MuSK ectodomain?

1997 • 90 citations

A universal oligonucleotide probe for acetylcholine receptor genes. Selection and sequencing of cDNA clones for the mouse muscle beta subunit.

1986 • 81 citations

Laminin induces acetylcholine receptor aggregation on cultured myotubes and enhances the receptor aggregation activity of a neuronal factor

1983 • 79 citations

Binding of the nicotinic acetylcholine receptor to SH2 domains of Fyn and Fyk protein tyrosine kinases.

1994 • 71 citations

Determination of the tyrosine phosphorylation sites of the nicotinic acetylcholine receptor.

1991 • 70 citations

Immobilization of nicotinic acetylcholine receptors in mouse C2 myotubes by agrin-induced protein tyrosine phosphorylation.

1995 • 69 citations

Direct demonstration of MuSK involvement in acetylcholine receptor clustering through identification of agonist ScFv

1997 • 65 citations

Mechanism of agrin‐induced acetylcholine receptor aggregation

1992 • 64 citations

Molecular cloning of two abundant protein tyrosine kinases in Torpedo electric organ that associate with the acetylcholine receptor.

1993 • 61 citations

Comparison of innervation and agrin-induced tyrosine phosphorylation of the nicotinic acetylcholine receptor

1994 • 61 citations

Agrin-induced reorganization of extracellular matrix components on cultured myotubes: relationship to AChR aggregation.

1990 • 53 citations

The role of the cytoplasmic domains of individual subunits of the acetylcholine receptor in 43 kDa protein-induced clustering in COS cells

1994 • 47 citations

Tyrosine Phosphorylation of Nicotinic Acetylcholine Receptor Mediates Grb2 Binding

1997 • 45 citations

AChR phosphorylation and aggregation induced by an agrin fragment that lacks the binding domain for alpha-dystroglycan.

1996 • 42 citations

Increased expression of the 43-kD protein disrupts acetylcholine receptor clustering in myotubes

1993 • 37 citations

Clustering of GABAAReceptors by Rapsyn/43kD Proteinin Vitro

1997 • 37 citations

The Synapse-Associated Protein Rapsyn Regulates Tyrosine Phosphorylation of Proteins Colocalized at Nicotinic Acetylcholine Receptor Clusters

1996 • 36 citations

Nicotinic receptor-associated 43K protein and progressive stabilization of the postsynaptic membrane

1992 • 29 citations

Clusters of 43-kDa protein are absent from genetic variants of C2 muscle cells with reduced acetylcholine receptor expression

1989 • 22 citations

Deleted Work

1955 • 0 citations