Location of antigenic determinants of primary sequences of the subunits of nicotinic acetylcholine receptor by peptide mapping

Single-channel currents recorded from membrane of denervated frog muscle fibres

1976 • 2,456 citations

Structural homology of Torpedo californica acetylcholine receptor subunits

1983 • 798 citations

Primary structure of α-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence

1982 • 730 citations

Acetylcholine Receptor: Complex of Homologous Subunits

1980 • 594 citations

Sizing of protein A-colloidal gold probes for immunoelectron microscopy.

1981 • 573 citations

Amphipathic analysis and possible formation of the ion channel in an acetylcholine receptor.

1984 • 513 citations

Monoclonal antibodies used to probe acetylcholine receptor structure: localization of the main immunogenic region and detection of similarities between subunits.

1980 • 452 citations

Cloning and sequence analysis of calf cDNA and human genomic DNA encoding α-subunit precursor of muscle acetylcholine receptor

1983 • 433 citations

Nucleotide and deduced amino acid sequences of Torpedo californica acetylcholine receptor gamma subunit.

1983 • 412 citations

Mapping of surface structures of electrophorus acetylcholine receptor using monoclonal antibodies.

1981 • 412 citations

Identification of the alpha subunit half-cystine specifically labeled by an affinity reagent for the acetylcholine receptor binding site.

1984 • 408 citations

Ion‐concentration dependence of the reversal potential and the single channel conductance of ion channels at the frog neuromuscular junction.

1979 • 394 citations

Location of functional regions of acetylcholine receptor α-subunit by site-directed mutagenesis

1985 • 390 citations

Molecular weight in detergent solution of acetylcholine receptor from Torpedo californica

1978 • 384 citations

Large‐Scale Purification of the Acetylcholine‐Receptor Protein in Its Membrane‐Bound and Detergent‐Extracted Forms from Torpedo marmorata Electric Organ

1977 • 375 citations

Acetylcholine and local anesthetic binding to Torpedo nicotinic postsynaptic membranes after removal of nonreceptor peptides.

1979 • 350 citations

Specificities of antibodies to acetylcholine receptors in sera from myasthenia gravis patients measured by monoclonal antibodies.

1982 • 342 citations

Complete mRNA coding sequence of the acetylcholine binding alpha-subunit of Torpedo marmorata acetylcholine receptor: a model for the transmembrane organization of the polypeptide chain.

1983 • 332 citations

Quaternary structure of the acetylcholine receptor

1985 • 281 citations

[29] Production and assay of antibodies to acetylcholine receptors

1981 • 277 citations

A structural model of the acetylcholine receptor channel based on partition energy and helix packing calculations

1984 • 260 citations

Biochemical properties of acetylcholine receptor subunits from Torpedo californica

1979 • 239 citations

Diazotizable arylamine cellulose papers for the coupling and hybridization of nucleic acids

1982 • 218 citations

The molecular cloning and characterisation of cDNA coding for the α subunit of the acetyl-choline receptor

1982 • 176 citations

Purification of Torpedo californica post-synaptic membranes and fractionation of their constituent proteins

1980 • 176 citations

The preparation of colloidal gold particles using tannic acid as an additional reducing agent

1982 • 174 citations

Immunospecific identification and three-dimensional structure of a membrane-bound acetylcholine receptor from Torpedo californica

1979 • 153 citations

Immunobiology of Myasthenia Gravis, Experimental Autoimmune Myasthenia Gravis, and Lambert-Eaton Syndrome

1985 • 145 citations

Demonstration of a main immunogenic region on acetylcholine receptors from human muscle using monoclonal antibodies to human receptor

1983 • 139 citations

A morphological study of the cholinergic receptor protein from Torpedo marmorata in its membrane environment and in its detergent-extracted purified form

1978 • 130 citations

Selectivity of cations and nonelectrolytes for acetylcholine-activated channels in cultured muscle cells.

1978 • 127 citations

Characteristics of monoclonal antibodies to denatured Torpedo and to native calf acetylcholine receptors: Species, subunit and region specificity

1986 • 127 citations

Monoclonal antibodies to cytoplasmic domains of the acetylcholine receptor.

1983 • 118 citations

Monoclonal antibodies as probes of acetylcholine receptor structure. 1. Peptide mapping

1981 • 115 citations

Signal recognition protein is required for the integration of acetylcholine receptor delta subunit, a transmembrane glycoprotein, into the endoplasmic reticulum membrane.

1982 • 112 citations

Immunochemical similarities between subunits of acetylcholine receptors from Torpedo, Electrophorus, and mammalian muscle

1979 • 110 citations

Role of the main immunogenic region of acetylcholine receptor in myasthenia gravis. An Fab monoclonal antibody protects against antigenic modulation by human sera.

1985 • 106 citations

Evidence for unpredicted transmembrane domains in acetylcholine receptor subunits.

1985 • 103 citations

Topological mapping of acetylcholine receptor: evidence for a model with five transmembrane segments and a cytoplasmic COOH-terminal peptide.

1985 • 101 citations

Region of peptide 125-147 of acetylcholine receptor alpha subunit is exposed at neuromuscular junction and induces experimental autoimmune myasthenia gravis, T-cell immunity, and modulating autoantibodies.

1985 • 98 citations

STRUCTURE AND FUNCTION OF THE ACETYLCHOLINE RECEPTOR MOLECULE STUDIED USING MONOCLONAL ANTIBODIES

1981 • 90 citations

Structure and transmembrane nature of the acetylcholine receptor in amphibian skeletal muscle as revealed by cross-reacting monoclonal antibodies.

1984 • 90 citations

Crystalline arrays of membrane-bound acetylcholine receptor.

1981 • 89 citations

An analysis by low-angle neutron scattering of the structure of the acetylcholine receptor from Torpedo californica in detergent solution

1979 • 71 citations

Immunochemical tests of acetylcholine receptor subunit models

1984 • 68 citations

Identification of exposed and buried determinants of the membrane-bound acetylcholine receptor from Torpedo californica

1981 • 67 citations

Structural details of membrane-bound acetylcholine receptor from Tropedo marmorata.

1980 • 65 citations

Cytoplasmic surface structure in postsynaptic membranes from electric tissue visualized by tannic-acid-mediated negative contrasting.

1982 • 62 citations

Immunochemical demonstration that amino acids 360-377 of the acetylcholine receptor gamma-subunit are cytoplasmic.

1985 • 58 citations

Structural features of the nicotinic acetylcholine receptor revealed by antibodies to synthetic peptides

1984 • 53 citations

A discontinuous electrophoretic system for separating peptides on polyacrylamide gels

1983 • 50 citations

Image analysis of the heavy form of the acetylcholine receptor from Torpedo marmorata

1984 • 45 citations

Transmembrane orientation of an early biosynthetic form of acetylcholine receptor delta subunit determined by proteolytic dissection in conjunction with monoclonal antibodies

1983 • 42 citations

Effects of monoclonal antibodies on the function of acetylcholine receptors purified from Torpedo californica and reconstituted into vesicles

1985 • 41 citations

Antigenic sites of the nicotinic acetylcholine receptor cannot be predicted from the hydrophilicity profile

1984 • 39 citations

Localization of a highly immunogenic region on the acetylcholine receptor α-subunit

1986 • 35 citations

Monoclonal antibodies specific to the beta and gamma subunits of the Torpedo acetylcholine receptor inhibit single-channel activity

1986 • 34 citations

The ontogeny of regulatory peptide-containing cells in the human fetal stomach: an immunocytochemical study.

1983 • 29 citations

Structural localization of the sequence α235–242 of the nicotinic acetylcholine receptor

1985 • 29 citations

Comparison of the subunit structure of acetylcholine receptors from muscle and electric organ of Electrophorus electricus

1983 • 20 citations

Ultrastructural immunocytochemistry of particulate fractions using polyvinyl chloride microculture wells.

1984 • 18 citations