Characteristics of monoclonal antibodies to denatured Torpedo and to native calf acetylcholine receptors: Species, subunit and region specificity

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

Structural homology of Torpedo californica acetylcholine receptor subunits

1983 • 798 citations

Acetylcholine Receptor: An Allosteric Protein

1984 • 620 citations

Acetylcholine Receptor: Complex of Homologous Subunits

1980 • 594 citations

Amphipathic analysis and possible formation of the ion channel in an acetylcholine receptor.

1984 • 513 citations

The Nicotinic Cholinergic Receptor: Correlation of Molecular Structure with Functional Properties

1982 • 456 citations

Monoclonal antibodies used to probe acetylcholine receptor structure: localization of the main immunogenic region and detection of similarities between subunits.

1980 • 452 citations

Cloning and sequence analysis of calf cDNA and human genomic DNA encoding α-subunit precursor of muscle acetylcholine receptor

1983 • 433 citations

Mapping of surface structures of electrophorus acetylcholine receptor using monoclonal antibodies.

1981 • 412 citations

Rat × rat hybrid myelomas and a monoclonal anti-Fd portion of mouse IgG

1979 • 411 citations

Molecular weight in detergent solution of acetylcholine receptor from Torpedo californica

1978 • 384 citations

Expression of functional acetylcholine receptor from cloned cDNAs

1984 • 366 citations

Interspecies spleen-myeloma hybrid producing monoclonal antibodies against mouse lymphocyte surface glycoprotein, T200.

1978 • 282 citations

[29] Production and assay of antibodies to acetylcholine receptors

1981 • 277 citations

Immunology of acetylcholine receptors in relation to myasthenia gravis.

1980 • 255 citations

Biochemical properties of acetylcholine receptor subunits from Torpedo californica

1979 • 239 citations

Assembly in vivo of mouse muscle acetylcholine receptor: Identification of an α subunit species that may be an assembly intermediate

1983 • 204 citations

Inhibition of glycosylation with tunicamycin blocks assembly of newly synthesized acetylcholine receptor subunits in muscle cells.

1982 • 193 citations

Monoclonal antibodies as probes of acetylcholine receptor structure. 2. Binding to native receptor

1981 • 157 citations

Demonstration of a main immunogenic region on acetylcholine receptors from human muscle using monoclonal antibodies to human receptor

1983 • 139 citations

Molecular Structure of the Nicotinic Acetylcholine Receptor

1983 • 138 citations

Shared antigenic determinant between the Electrophorus acetylcholine receptor and a synaptic component on chicken ciliary ganglion neurons.

1984 • 136 citations

Primary structure of delta subunit precursor of calf muscle acetylcholine receptor deduced from cDNA sequence

1985 • 134 citations

Monoclonal antibodies to cytoplasmic domains of the acetylcholine receptor.

1983 • 118 citations

Monoclonal antibodies as probes of acetylcholine receptor structure. 1. Peptide mapping

1981 • 115 citations

Alpha and beta subunits of the nicotinic acetylcholine receptor contain covalently bound lipid.

1984 • 106 citations

Role of the main immunogenic region of acetylcholine receptor in myasthenia gravis. An Fab monoclonal antibody protects against antigenic modulation by human sera.

1985 • 106 citations

Mapping the binding of monoclonal antibodies to the acetylcholine receptor from Torpedo californica

1983 • 99 citations

High affinity binding of alpha-bungarotoxin to the purified alpha-subunit and to its 27,000-dalton proteolytic peptide from Torpedo marmorata acetylcholine receptor. Requirement for sodium dodecyl sulfate.

1983 • 97 citations

STRUCTURE AND FUNCTION OF THE ACETYLCHOLINE RECEPTOR MOLECULE STUDIED USING MONOCLONAL ANTIBODIES

1981 • 90 citations

Structure and transmembrane nature of the acetylcholine receptor in amphibian skeletal muscle as revealed by cross-reacting monoclonal antibodies.

1984 • 90 citations

Characterization of a component in chick ciliary ganglia that cross- reacts with monoclonal antibodies to muscle and electric organ acetylcholine receptor

1985 • 88 citations

Acetylcholine receptors from Torpedo and Electrophorus have similar subunit structures

1980 • 73 citations

Monoclonal antibodies in endocrine research

1982 • 72 citations

Subunit Organization and Structure of an Acetylcholine Receptor

1983 • 70 citations

Immunochemical tests of acetylcholine receptor subunit models

1984 • 68 citations

Primary structure of gamma subunit precursor of calf-muscle acetylcholine receptor deduced from the cDNA sequence

1984 • 68 citations

Identification of exposed and buried determinants of the membrane-bound acetylcholine receptor from Torpedo californica

1981 • 67 citations

Subunit composition of bovine muscle acetylcholine receptor

1982 • 61 citations

Use of Monoclonal Antibodies to Study Acetylcholine Receptors from Electric Organs, Muscle, and Brain and the Autoimmune Response to Receptor in Myasthenia Gravis

1983 • 59 citations

Identification of a cDNA clone coding for the acetylcholine binding subunit of Torpedo marmorata acetylcholine receptor.

1982 • 56 citations

Structural features of the nicotinic acetylcholine receptor revealed by antibodies to synthetic peptides

1984 • 53 citations

Lipid-dependent recovery of alpha-bungarotoxin and monoclonal antibody binding to the purified alpha-subunit from Torpedo marmorata acetylcholine receptor. Enhancement by noncompetitive channel blockers.

1984 • 48 citations

cDNA clone for the alpha subunit of the acetylcholine receptor from the mouse muscle cell line BC3H-1.

1983 • 47 citations

Hybridoma Technology in the Biosciences and Medicine

1985 • 46 citations

Transmembrane orientation of an early biosynthetic form of acetylcholine receptor delta subunit determined by proteolytic dissection in conjunction with monoclonal antibodies

1983 • 42 citations

Effects of monoclonal antibodies on the function of acetylcholine receptors purified from Torpedo californica and reconstituted into vesicles

1985 • 41 citations

Antigenic sites of the nicotinic acetylcholine receptor cannot be predicted from the hydrophilicity profile

1984 • 39 citations

Characterization of the mRNA for mouse muscle acetylcholine receptor alpha subunit by quantitative translation in vitro.

1983 • 36 citations

Myasthenia gravis: immunobiology of a receptor disorder

1983 • 31 citations

Monoclonal antibodies as probes of the acetylcholine receptor and myasthenia gravis

1984 • 25 citations

Structural similarities between acetylcholine receptors from fish electric organs and mammalian muscle

1982 • 23 citations

Spectrotypic analysis of antibodies to acetylcholine receptors in experimental autoimmune myasthenia gravis.

1984 • 23 citations

The main immunogenic region of acetylcholine receptors does not provoke the formation of antibodies of a predominant idiotype

1985 • 22 citations

Comparison of the subunit structure of acetylcholine receptors from muscle and electric organ of Electrophorus electricus

1983 • 20 citations

Purification of acetylcholine receptors from the muscle of Electrophorus electricus

1983 • 15 citations

Myasthenia Gravis: Pathophysiology and Management.

1982 • 14 citations

Myasthenia Gravis and the Nicotinic Cholinergic Receptor

1981 • 12 citations

Production of Rat × Mouse Hybridomas for the Study of the Nicotinic Acetylcholine Receptor

1985 • 7 citations

Comparison of embryonic and adult torpedo acetylcholine receptor by sedimentation characteristics and antigenicity

1984 • 1 citations